Anti-inflammatory activity of piperine.

Mujumdar Arvind Manohar, Dhuley Jayant Nilkanth, Deshmukh Vinaykumar Keshav, Raman Palghat Hariharan, Naik Suresh Ramnath
Japanese Journal of Medical Science and Biology, 1990

Abstract

Piperine (1-peperoyl piperidine) was isolated from Piper nigrum Linn for the evaluation of anti-inflammatory activity in rats. Different acute and chronic experimental models like carrageenin-induced rat paw edema, cotton pellet granuloma, and croton oil-induced granuloma pouch, were employed. Simultaneously, biochemical estimations were made to elucidate the underlying mechanism of the action. Piperine acted significantly on early acute changes in inflammatory processes and chronic granulative changes. It also acted partially through stimulation of pituitary adrenal axis. Exudative changes in both acute and chronic models, however, were insignificant.

PMID:2283727
Category:Weight Loss

The best supplements with Piper Nigrum in Weight Loss category: Fast Burn Extreme, Piperinox.

Articles similar to "Anti-inflammatory activity of piperine."

Previous article

FLAVONOIDS, POLIFENOLS CONTENT AND ANTIOXIDANT ACTIVITY OF CITRUS FRUITS EXTRACTS.

Next article

Effects of piperine on memory and behavior mediated via monoamine neurotransmiters.