Andrade Chittaranjan, et al.
Indian journal of psychiatry, 2000
Abstract
A double-blind, placebo-controlled study was conducted to evaluate the efficacy an ethanolic extract of Aswagandha (Withania somnifera), in patients with ICD-10 anxiety disorders. The sample comprised 39 subjects, of whom 20 received the drug and 19 received placebo. The two groups were sociodemographically and clinically similar at baseline. At 2 and 6 weeks follow-up, data from approximately 85% of patients in each group were available for analysis. Statistical trends favouring the drug were observed at both time points. At 6 weeks, significantly more patients met a priori response criteria in the drug group (88.2%) as compared with the placebo group (50%). The drug was well-tolerated and did not occasion more adverse effects than did placebo. It is concluded that this ethanolic extract of Withania somnifera has useful anxiolytic potential and merits further investigation.
Keywords
Anxiety disorder; Aswagandha; Ayurvedic treatment; adjustment disorder with anxiety; clinical trial; generalized anxiety disorder; herbal therapy; panic disorder
| PMID: | 21407960 |
|---|---|
| Category: | Brain / Mental Clarity |
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Pharmacologic overview of Withania somnifera, the Indian Ginseng.