Ahmadian Mehdi, Dabidi Roshan Valiollah, Ashourpore Eadeh
Journal of dietary supplements, 2017
Abstract
Background
Taurine is an amino acid found abundantly in the heart in very high concentrations. It is assumed that taurine contributes to several physiological functions of mammalian cells, such as osmoregulation, anti-inflammation, membrane stabilization, ion transport modulation, and regulation of oxidative stress and mitochondrial protein synthesis. The objective of the current study was to evaluate the effectiveness of taurine supplementation on functional capacity, myocardial oxygen consumption, and electrical activity in patients with heart failure.
Methods
In a double-blind and randomly designed study, 16 patients with heart failure were assigned to two groups: taurine (TG, n = 8) and placebo (PG, n = 8). TG received 500-mg taurine supplementation three times per day for two weeks.
Results
Significant decrease in the values of Q-T segments (p < 0.01) and significant increase in the values of P-R segments (p < 0.01) were detected following exercise post-supplementation in TG rather than in PG. Significantly higher values of taurine concentration, T wave, Q-T segment, physical capacities, and lower values of cardiovascular capacities were detected post-supplementation in TG as compared with PG (all p values <0.01).
Conclusions
Taurine significantly enhanced the physical function and significantly reduced the cardiovascular function parameters following exercise. Our results also suggest that the short-term taurine supplementation is an effective strategy for improving some selected hemodynamic parameters in heart failure patients. Together, these findings support the view that taurine improves cardiac function and functional capacity in patients with heart failure. This idea warrants further study.
Keywords
electrocardiographic; heart failure; incremental exercise; rate pressure product; taurine
| PMID: | 28118062 |
|---|---|
| Category: | Heart Health |
The best supplements with Taurine in Heart Health category:
- Magnesium & Potassium Aspartate, 120 Capsules (Now Foods) - Magnesium and Potassium are two minerals that are ubiquitous throughout the body and play fundamental roles in cell and tissue health. It contains among others: Taurine.
Articles similar to "Taurine Supplementation Improves Functional Capacity, Myocardial Oxygen Consumption, and Electrical Activity in Heart Failure."
- The role of Taurine in Heart Health: Taurine supplementation has anti-atherogenic and anti-inflammatory effects before and after incremental exercise in heart failure. ( The purpose of this study was to examine the anti-atherogenic and anti-inflammatory effect of supplemental taurine prior to and following incremental exercise in patients with heart failure (HF)... Our results suggest that 2 weeks of oral taurine supplementation increases the taurine levels and has anti-atherogenic and anti-inflammatory effects prior to and following incremental exercise in HF patients. )