Huang Zhiyi, et al.
Journal of clinical medicine, 2018
Abstract
Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium and mucus integrity in the body. VitA is known as an anti-inflammation vitamin because of its critical role in enhancing immune function. VitA is involved in the development of the immune system and plays regulatory roles in cellular immune responses and humoral immune processes. VitA has demonstrated a therapeutic effect in the treatment of various infectious diseases. To better understand the relationship between nutrition and the immune system, the authors review recent literature about VitA in immunity research and briefly introduce the clinical application of VitA in the treatment of several infectious diseases.
Keywords
immunology; infectious disease; vitamin A.
Conflict of interest statement
The authors declare no conflict of interest.Figures
Transformation of retinol into bioactive retinoic acid involves a two-step oxidative reaction. To do this, a group of enzymes, divided in three families, will act together to form the final compound retinoic acid (RA). Retinol transforms into retinal under the catalytic action of the alcohol dehydrogenase (ADH) family; this step can also be regulated by the short-chain dehydrogenase/reductase family, which shows a wide affinity for alcohols and aldehydes. The aldehyde dehydrogenase (RALDH) family then catalyzes retinal to form retinoic acid. Both of the oxidation reactions transmit electrons through the electron acceptor NAD or NADP.
| PMID: | 30200565 |
|---|---|
| DOI: | 10.3390/jcm7090258 |
| PMCID (Free PMC Article): | PMC6162863 |
| Category: | Immune |
The best supplements with Retinol in Immune category:
- Immune Defence - Zinc Lozenges with Rosehip and Acerola - Your immune system needs daily support to stay in good form, to be able to fight off any pathogens trying to enter your system and to witstand the impact of stress on your body and mind. It contains among others: Retinol.
- Vitamin A, 25,000 IU, 250 Softgels (Now Foods) - Vitamin A is essential for the maintenance of the tissues that line the internal and external surfaces of the body, including the eyes, skin, respiratory, GI and urinary tracts. It contains among others: Retinol.
- Vitamin A, 10,000 IU, 100 Softgels (Now Foods) - Vitamin A is essential for the maintenance of the tissues that line the internal and external surfaces of the body, including the eyes, skin, respiratory, GI and urinary tracts. It contains among others: Retinol.
Previous article
Zinc, Aging, and Immunosenescence: An Overview.