McGlade Erin, Agoston A. M., DiMuzio J., Kizaki M., Nakazaki E., Kamiya T., Yurgelun-Todd D.
Journal of Attention Disorders, 2015
Abstract
Objective
This study assessed the effects of citicoline, a nutraceutical, on attention, psychomotor function, and impulsivity in healthy adolescent males.
Method
Seventy-five healthy adolescent males were randomly assigned to either the citicoline group ( n = 51 with 250 or 500 mg citicoline) or placebo ( n = 24). Participants completed the Ruff 2&7 Selective Attention Test, Finger Tap Test, and the Computerized Performance Test, Second Edition (CPT-II) at baseline and after 28 days of supplementation.
Results
Individuals receiving citicoline exhibited improved attention ( p = 0.02) and increased psychomotor speed ( p = 0.03) compared with those receiving placebo. Higher weight-adjusted dose significantly predicted increased accuracy on an attention task ( p = 0.01), improved signal detectability on a computerized attention task ( p = 0.03), and decreased impulsivity ( p = 0.01).
Discussion
Adolescent males receiving 28 days of Cognizin® citicoline showed improved attention and psychomotor speed and reduced impulsivity compared to adolescent males who received placebo.
| PMID: | 26179181 |
|---|---|
| Category: | Brain / Mental Clarity |
The best supplements with Citicoline in Brain / Mental Clarity category:
- Brain Pill - „An amazing new product that supports your brain health and has the potential to change your life returning laser-sharp mental clarity” - Dr Dave David, a surgeon and physician for more than 37 years. It contains among others: Citicoline.
Articles similar to "The effect of citicoline supplementation on motor speed and attention in adolescent males."
- The significance of Citicoline for Brain / Mental Clarity: Improvements in concentration, working memory and sustained attention following consumption of a natural citicoline–caffeine beverage. (This study examined the neurocognitive and electrophysiological effects of a citicoline-caffeine-based beverage in 60 healthy adult participants enrolled in a randomized, double-blind, placebo-controlled trial...)
- The role of Citicoline in Brain / Mental Clarity: The role of citicoline in cognitive impairment: pharmacological characteristics, possible advantages, and doubts for an old drug with new perspectives. (Citicoline is able to potentiate neuroplasticity and is a natural precursor of phospholipid synthesis, or rather serves as a choline source in the metabolic pathways for biosynthesis of acetylcholine...Citicoline appears to be a promising agent to improve cognitive impairment, especially of vascular origin. In fact, so far it appears as a drug with the ability to promote "safe" neuroprotection, capable of enhancing endogenous protective. Large clinical trials are needed to confirm its benefits.)
- The impact of Citicoline on Brain / Mental Clarity: Citicoline (Cognizin) in the treatment of cognitive impairment. (Pharmacological treatment of cerebrovascular disorders was introduced at the beginning of the 20th Century...Citicoline appears to be a promising agent to improve cognitive impairment, especially of vascular origin. In fact, so far it appears as a drug with the ability to promote "safe" neuroprotection, capable of enhancing endogenous protective. Large clinical trials are needed to confirm its benefits.)
- The significance of Citicoline for Brain / Mental Clarity: Citicoline in the treatment of cognitive and behavioral disorders in pathologic senile decline. (A three months study was performed on 150 aging patients with primary memory deficits in order to verify the effectiveness of CDP-Choline, administered in repeated cycles of four weeks, with an interval of one week between cycles, in improving patients' cognitive and behavioral efficiency and in stabilizing their cognitive decline...Citicoline appears to be a promising agent to improve cognitive impairment, especially of vascular origin. In fact, so far it appears as a drug with the ability to promote "safe" neuroprotection, capable of enhancing endogenous protective. Large clinical trials are needed to confirm its benefits.)
- The impact of Citicoline on Brain / Mental Clarity: Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women. (OBJECTIVE: The present study assessed the potential cognitive-enhancing effects of citicoline, a dietary supplement, in healthy adult women... After 28 days of daily citicoline supplementation, participants who were administered either the 250 mg or the 500 mg citicoline doses showed significantly better ability to produce correct responses on the CPT-II, likely due to improved cognitive inhibition. Our findings suggest that citicoline may improve attentional performance in middle-aged women and may ameliorate attentional deficits associated with central nervous system disorders.)
- The significance of Citicoline for Brain / Mental Clarity: Citicoline improves memory performance in elderly subjects. (Citicoline is a choline donor involved in the biosynthesis of brain phospholipids and acetylcholine extensively used in the treatment of neurodegenerative diseases... After 28 days of daily citicoline supplementation, participants who were administered either the 250 mg or the 500 mg citicoline doses showed significantly better ability to produce correct responses on the CPT-II, likely due to improved cognitive inhibition. Our findings suggest that citicoline may improve attentional performance in middle-aged women and may ameliorate attentional deficits associated with central nervous system disorders.)
- The role of Citicoline in Brain / Mental Clarity: Neuroprotective properties of citicoline: facts, doubts and unresolved issues. (Citicoline is the generic name of the pharmaceutical substance that chemically is cytidine-5'-diphosphocholine (CDP-choline), which is identical to the natural intracellular precursor of phospholipid phosphatidylcholine... After 28 days of daily citicoline supplementation, participants who were administered either the 250 mg or the 500 mg citicoline doses showed significantly better ability to produce correct responses on the CPT-II, likely due to improved cognitive inhibition. Our findings suggest that citicoline may improve attentional performance in middle-aged women and may ameliorate attentional deficits associated with central nervous system disorders.)
- The impact of Citicoline on Brain / Mental Clarity: Citicoline-Pharmacological and Clinical Review, 2006 Update. (Cytidine 5'-diphosphocholine, CDP-choline, or citicoline is an essential intermediate in the biosynthetic pathway of structural phospholipids in cell membranes, particularly phosphatidylcholine... After 28 days of daily citicoline supplementation, participants who were administered either the 250 mg or the 500 mg citicoline doses showed significantly better ability to produce correct responses on the CPT-II, likely due to improved cognitive inhibition. Our findings suggest that citicoline may improve attentional performance in middle-aged women and may ameliorate attentional deficits associated with central nervous system disorders.)
- The significance of Citicoline for Brain / Mental Clarity: Citicoline: pharmacological and clinical review, 2010 update. (This review is based on the previous one published in 2006 -Secades JJ, Lorenzo JL... After 28 days of daily citicoline supplementation, participants who were administered either the 250 mg or the 500 mg citicoline doses showed significantly better ability to produce correct responses on the CPT-II, likely due to improved cognitive inhibition. Our findings suggest that citicoline may improve attentional performance in middle-aged women and may ameliorate attentional deficits associated with central nervous system disorders.)
- The role of Citicoline in Brain / Mental Clarity: “Brain-specific” nutrients: a memory cure?. (OBJECTIVE: We review the experimental evaluations of several widely marketed nonprescription compounds claimed to be memory enhancers and treatments for age-related memory decline... In sum, for most of the "brain-specific" nutrients we review, some mildly suggestive effects have been found in preliminary controlled studies using standard psychometric memory assessments or more general tests designed to reveal cognitive impairment. We suggest that future evaluations of the possible memory benefits of these supplements might fruitfully focus on memory processes rather than on memory tests per se.)
Previous article
Citicoline in the treatment of cognitive and behavioral disorders in pathologic senile decline.
Next article
Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women.