Ardalani Hamidreza, et al.
Complementary medicine research, 2019
Abstract
Background
Recent studies have suggested that artichoke (Cynara scolymus L.) may reduce certain biochemical blood factors but the efficacy of this plant on blood pressure (BP) has not yet been investigated. In this study, we determined the clinical efficacy of C. scolymuson BP and body mass index (BMI) in hypertensive patients as an adjunctive to captopril for the first time.
Methods
The total phenolic content and gas chromatography-mass spectrometry metabolite profiling in leaves of C. scolymus have been evaluated. A clinical trial was subsequently carried out on 40 patients to determine the effect of C. scolymus on BP and BMI in hypertensive patients. The treatment group received capsules containing C. scolymus(500 mg twice daily) and the placebo group received starch powder for 8 weeks. Systolic blood pressure (SBP), diastolic blood pressure, and BMI were determined before and after the study.
Results
A significant improvement of the BMI was seen in the C. scolymus group compared with the placebo group (p = 0.04).
Conclusions
Our findings demonstrated that the consumption of C. scolymus powder as a rich source of phenolic and antioxidant compounds could potentially improve BMI and SBP in hypertensive patients. Therefore, more trials are needed to confirm or reject the antihypertensive impact of artichoke.
© 2019 S. Karger AG, Basel.
Keywords
Artichoke; Blood pressure; Body mass index; Cynara scolymus L.; Hypertension; Overweight
| PMID: | 31484191 |
|---|---|
| Category: | General properties of Cynara Scolymus |
Articles similar to "The Effect of Cynara scolymus on Blood Pressure and BMI in Hypertensive Patients: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial."
- The properties of Cynara Scolymus: Pharmacological studies of artichoke leaf extract and their health benefits. (Artichoke (Cynara scolymus) leaf extract was one of the few herbal remedies which the clinical and experimental trials have complemented each other...)
- The properties of Cynara Scolymus: Artichoke leaf extract for treating hypercholesterolaemia. ( Hypercholesterolaemia is directly associated with an increased risk for coronary heart disease and other sequelae of atherosclerosis... Data from three clinical trials assessing ALE for treating hypercholesterolaemia are available. Athough the trials are of adequate methodological quality they have some shortcomings and one is available as abstract only. There is an indication that ALE has potential in lowering cholesterol levels, but the evidence is, as yet, not convincing. The limited data on safety suggest only mild, transient and infrequent adverse events with the short term use of ALE.)
Previous article
Artichoke leaf extract for treating hypercholesterolaemia.