Sampath Suneetha, et al.
Indian journal of physiology and pharmacology, 2015
Abstract
Introduction
Ocimum sanctum (OS), known as Holy basil, has been documented to possess neuroprotective, cognition-enhancing and stress relieving effects in animal models. However there is paucity of clinical studies to document these effects.
Materials and Methods
Effect of OS on parameters related to cognition and stress in humans was evaluated with administration of 300 milligram capsules of ethanolic leaf extracts of Ocimum sanctum (EtOS) or placebo per day, over 30 days.
Results
Intra-group comparison of Sternberg and Stroop test showed improvement in both the placebo and EtOS groups, however, the improvement stabilized after day 15 in the placebo group. Intergroup comparison revealed a significant improvement of the following cognitive parameters in the EtOS as compared to the placebo: reaction time (RT) and error rate (ER) of Sternberg test, RT of neutral task of Stroop, RT and ER of interference task of Stroop. The intra-group comparison of P300 latency, salivary cortisol, and State-Trait Anxiety Inventory showed improvement over time in the EtOS group alone, though the inter-group difference was significant in the P300 latency alone. There were no changes in heart rate (HR), AHR, or galvanic skin response (GSR) or AGSR.
Conclusion
Ocimum sanctum leaf extract seems to have potential cognition-enhancing properties in humans.
| PMID: | 26571987 |
|---|---|
| Category: | Brain / Mental Clarity |
The best supplements with Ocimum Tenuiflorum in Brain / Mental Clarity category:
- Mood Support with St. John's Wort, 90 Veg Capsules (Now Foods) - NOW Mood Support is a nutritional supplement that has both nutrients and herbal extracts that aid in the support of a healthy nervous system and a positive, balanced mood state. It contains among others: Ocimum Tenuiflorum.
Articles similar to "Holy Basil (Ocimum Sanctum Linn.) Leaf Extract Enhances Specific Cognitive Parameters in Healthy Adult Volunteers: A Placebo Controlled Study."
- The role of Ocimum Tenuiflorum in Brain / Mental Clarity: Evaluation of Anti-Amnesic Effect of Extracts of Selected Ocimum Species Using In-Vitro and In-Vivo Models. (Ethnopharmacological relevance: Ocimum species are traditionally used for the treatment of anxiety, nerve pain, convulsions and a variety of neurodegenerative disorders... OBE possesses antioxidant and AChE inhibitory activity. These biochemical changes are responsible for the anti-amnesic and neuroprotective activities of O. basilicum which may be attributed to the presence of phenolic and flavonoid compounds. This can be developed as an effective anti-amnesic drug. )
Previous article
Tulsi - Ocimum Sanctum: A Herb for All Reasons.