Sultana Bushra, et al.
Pakistan journal of pharmaceutical sciences, 2014
Abstract
The present work explores antimutagenic and antioxidant potential as well as total phenolics of aqueous and acidified methanol extractable components from clove (Syzygium aromaticum L.) seed. The magnitude of antimutagenic activity of clove seed extracts (CSE) against two mutant bacterial strains: S. typhimurium TA98 and S. typhimurium TA100 (Ames bacterial test) ranged from 34.11-79.74%. Antioxidant activity in terms of measurement of DPPH radical scavenging capacity and inhibition of linoleic acid peroxidation was noted to be 71.16-94.58% and 54.96-86.89%, respectively. CSE also exhibited an appreciable amount of total phenolics with contribution between 22.80 and 115.33 GAE mg/100g. A strong correlation between total phenolics and tested biological activities were recorded. The results of this study advocate that clove seed can be explored as a viable source of bioactives for the development of chemotherapeutic drugs against cancer in addition to acting as nutraceutical and functional food ingredient.
| PMID: | 25015457 |
|---|---|
| Category: | General properties of Syzygium Aromaticum |
Articles similar to "In vitro antimutagenic, antioxidant activities and total phenolics of clove (Syzygium aromaticum L.) seed extracts."
- The properties of Syzygium Aromaticum: Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint. (Eugenol is a hydroxyphenyl propene, naturally occurring in the essential oils of several plants belonging to the Lamiaceae, Lauraceae, Myrtaceae, and Myristicaceae families...)
- The properties of Syzygium Aromaticum: Antibacterial activity of Syzygium aromaticum seed: Studies on oxidative stress biomarkers and membrane permeability. (Oxidative stress and membrane permeability as mode of antibacterial activity of aqueous extract of Syzygium aromaticum seeds against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus was investigated...)
- The properties of Syzygium Aromaticum: Antimicrobial and antioxidant activity of unencapsulated and encapsulated clove (Syzygium aromaticum, L.) essential oil. (Clove (Syzygium aromaticum, L...)
- The properties of Syzygium Aromaticum: Potential alternative treatment of ocular bacterial infections by oil derived from syzygium aromaticum flower (Clove). (Purpose/Aim: This study aims to evaluate the predisposing risk factors and antibiotic resistance of bacterial corneal ulcer to commonly used antibiotics... The current study showed that S. aromaticum oil had high antibacterial activity that could be helpful in the treatment of ocular bacterial infections to minimizing the possible side effects of commonly used antibiotic. )
- The properties of Syzygium Aromaticum: Antibacterial and antibiofilm activities of eugenol from essential oil of Syzygium aromaticum (L.) Merr. & L. M. Perry (clove) leaf against periodontal pathogen Porphyromonas gingivalis. (The antibacterial effect and mechanism of eugenol from Syzygium aromaticum (L... The current study showed that S. aromaticum oil had high antibacterial activity that could be helpful in the treatment of ocular bacterial infections to minimizing the possible side effects of commonly used antibiotic. )
- The properties of Syzygium Aromaticum: Anticancer potential of Syzygium aromaticum L. in MCF-7 human breast cancer cell lines. ( The common treatment for cancer is unfavorable because it causes many detrimental side effects, and lately, there has been a growing resistance toward anticancer drugs, which worsens the future of cancer treatment... Cloves are natural products with excellent cytotoxicity toward MCF-7 cells; thus, they are promising sources for the development of anticancer agents. )