Taipale Teemu, et al.
Pediatric research, 2016
Abstract
Background
Specific probiotic bacteria have proven to be effective in the prevention and treatment of infectious diseases in early life in at-risk populations. The impact of administration of Bifidobacterium animalis subsp. lactis BB-12 (BB-12) on the risk of acute infectious diseases was studied in healthy children.
Methods
In this double-blind, placebo-controlled study, 109 1-mo-old infants were assigned randomly to a probiotic group receiving a BB-12-containing tablet (n = 55) or a placebo (n = 54). Test tablets were administered to the infants twice a day (daily dose of BB-12 10 billion colony-forming units) until the age of 2 y with a novel slow-release pacifier or a spoon. Breastfeeding habits, pacifier use, dietary habits, medications, and all signs and symptoms of acute infections were registered in diaries by parents and in questionnaires by trained professionals.
Results
The infants receiving BB-12 were reported to have experienced fewer respiratory tract infections (RTIs; 87 vs. 100%; risk ratio: 0.87; 95% confidence interval: 0.76, 1.00; P = 0.033) than the controls. No significant differences between the groups were observed in reported gastrointestinal symptoms, otitis media, or fever. The baseline characteristics of the two groups were similar, as was the duration of breastfeeding.
Conclusion
Administration of BB-12 in early childhood may reduce RTIs.
| PMID: | 26372517 |
|---|---|
| DOI: | 10.1038/pr.2015.174 |
| Category: | General properties of Bifidobacterium Animalis |
Articles similar to "Bifidobacterium Animalis Subsp. Lactis BB-12 in Reducing the Risk of Infections in Early Childhood."
- The properties of Bifidobacterium Animalis: Age-Related Changes in the Composition of Gut Bifidobacterium Species. (Bifidobacteria are one of the major components in human microbiota that are suggested to function in maintaining human health...)
- The properties of Bifidobacterium Animalis: Bifidobacterium Animalis Subsp. Lactis BB-12 in Reducing the Risk of Infections in Infancy. (The impact of controlled administration of Bifidobacterium animalis subsp...)
Previous article
Bifidobacterium Animalis Subsp. Lactis BB-12 in Reducing the Risk of Infections in Infancy.