Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects.

Gulluni Nadia, et al.
Evidence-Based Complementary and Alternative Medicine, 2018

Abstract

We examined the effects of essential oil from legal (THC <0.2% w/v) hemp variety on the nervous system in 5 healthy volunteers. GC/EIMS and GC/FID analysis of the EO showed that the main components were myrcene and β-caryophyllene. The experiment consisted of measuring autonomic nervous system (ANS) parameters; evaluations of the mood state; and electroencephalography (EEG) recording before treatment, during treatment, and after hemp inhalation periods as compared with control conditions. The results revealed decreased diastolic blood pressure, increased heart rate, and significant increased skin temperature. The subjects described themselves as more energetic, relaxed, and calm. The analysis EEG showed a significant increase in the mean frequency of alpha (8-13 Hz) and significant decreased mean frequency and relative power of beta 2 (18,5-30 Hz) waves. Moreover, an increased power, relative power, and amplitude of theta (4-8 Hz) and alpha brain waves activities and an increment in the delta wave (0,5-4 Hz) power and relative power was recorded in the posterior region of the brain. These results suggest that the brain wave activity and ANS are affected by the inhalation of the EO of Cannabis sativa suggesting a neuromodular activity in cases of stress, depression, and anxiety.

PMID:29576792
DOI:10.1155/2018/1709182
PMCID (Free PMC Article):PMC5822802
Category:Brain / Mental Clarity

Articles similar to "Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects."

Previous article

Cannabidiol as a Potential Treatment for Anxiety Disorders.

Next article

A Systematic Review of the Effect of Cannabidiol on Cognitive Function: Relevance to Schizophrenia.