Tardy Anne-Laure, et al.
Nutrients, 2020
Abstract
Vitamins and minerals are essential to humans as they play essential roles in a variety of basic metabolic pathways that support fundamental cellular functions. In particular, their involvement in energy-yielding metabolism, DNA synthesis, oxygen transport, and neuronal functions makes them critical for brain and muscular function. These, in turn, translate into effects on cognitive and psychological processes, including mental and physical fatigue. This review is focused on B vitamins (Vitamin B1, Vitamin B2, Vitamin B3, Vitamin B5, Vitamin B6, Vitamin B8, Vitamin B9 and Vitamin B12), Vitamin C, iron, magnesium and zinc, which have recognized roles in these outcomes. It summarizes the biochemical bases and actions of these micronutrients at both the molecular and cellular levels and connects them with cognitive and psychological symptoms, as well as manifestations of fatigue that may occur when status or supplies of these micronutrients are not adequate.
Keywords
B vitamins; anemia; cognition; energy production; iron; magnesium; mental and physical fatigue; mood.; vitamin C; zinc.
Conflict of interest statement
A.-L.T., E.P., D.M. and C.S., are current employees of Sanofi. AS has not received fees or funding in relation to this publication. However, he has received research funding and/or consultancy/travel/speaker fees from several government research councils and several food and pharmaceutical companies, including a 2013/14 research grant from Sanofi, which was unrelated to this publication.| PMID: | 31963141 |
|---|---|
| PMCID (Free PMC Article): | PMC7019700 |
| DOI: | 10.3390/nu12010228 |
| Category: | Energy |
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