Patrulea Viorica, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 2015
Abstract
Chitosan and its derivatives have attracted great attention due to their properties beneficial for application to wound healing. The main focus of the present review is to summarize studies involving chitosan and its derivatives, especially N,N,N-trimethyl-chitosan (TMC), N,O-carboxymethyl-chitosan (CMC) and O-carboxymethyl-N,N,N-trimethyl-chitosan (CMTMC), used to accelerate wound healing. Moreover, formulation strategies for chitosan and its derivatives, as well as their in vitro, in vivo and clinical applications in wound healing are described.
Copyright © 2015 Elsevier B.V. All rights reserved.
Keywords
Biopolymers; Carboxymethyl chitosan; Chitosan; Chitosan (PubChem CID: 21896651); Chitosan derivatives; Drug delivery; Polyelectrolytes; Skin regeneration; Trimethyl chitosan; Wound dressings; Wound healing
| PMID: | 26614560 |
|---|---|
| Category: | General properties of Chitosan |
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