Sheng Yezhou, et al.
Journal of ethnopharmacology, 2005
Abstract
Historic medicinal practice has defined Cat's Claw, also known as Una de Gato or Uncaria tomentosa, as an effective treatment for several health disorders including chronic inflammation, gastrointestinal dysfunction such as ulcers, tumors and infections. The efficacy of Cat's Claw was originally believed, as early as the 1960s, to be due to the presence of oxindole alkaloids. However, more recently water-soluble Cat's Claw extracts were shown not to contain significant amounts of alkaloids (<0.05%), and yet still were shown to be very efficacious. Here we characterize the active ingredients of a water-soluble Cat's Claw extract called C-Med-100 as inhibiting cell growth without cell death thus providing enhanced opportunities for DNA repair, and the consequences thereof, such as immune stimulation, anti-inflammation and cancer prevention. The active ingredients were chemically defined as quinic acid esters and could also be shown to be bioactive in vivo as quinic acid.
| PMID: | 15619581 |
|---|---|
| DOI: | 10.1016/j.jep.2004.10.002 |
| Category: | General properties of Uncaria Tomentosa |
Articles similar to "An Active Ingredient of Cat's Claw Water Extracts Identification and Efficacy of Quinic Acid."
- The properties of Uncaria Tomentosa: In Vitro Effects of Two Extracts and Two Pure Alkaloid Preparations of Uncaria Tomentosa on Peripheral Blood Mononuclear Cells. (In the traditional Peruvian medicine, hot aqueous extracts of Uncaria tomentosa have been used for the treatment of a wide range of health problems, particularly digestive complaints and arthritis...)