Effectiveness of Vaginal Administration of Lactobacillus Rhamnosus Following Conventional Metronidazole Therapy: How to Lower the Rate of Bacterial Vaginosis Recurrences.

Marcone Valentina, et al.
The new microbiologica, 2008

Abstract

Eighty-four patients with bacterial vaginosis diagnosed according to Amsel's criteria were randomized to receive either oral metronidazole 500 mg twice a day for seven days, or one vaginal tablet containing freeze-dried Lactobacillus rhamnosus once a week at bedtime for two months starting one week after the last antibiotic administration. Followup was performed at days 30, 90 and 180. Chi-squared analysis showed a significant difference between the two treatment groups at day 90 (P = 0.05). Safe and effective long-term vaginal administration of Lactobacillus rhamnosus appears to be a useful complementary approach in the management of bacterial vaginosis.

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