Ascorbic Acid: Its Role in Immune System and Chronic Inflammation Diseases.

Sorice Angela, et al.
Mini reviews in medicinal chemistry, 2014

Abstract

Ascorbic acid (AA), also known as vitamin C, was initially identified as the factor preventing the scurvy disease, and became very popular for its antioxidant properties. It is an important co-substrate of a large class of enzymes, and regulates gene expression by interacting with important transcription factors. AA is important in all stressful conditions that are linked to inflammatory processes and involve immunity. It has been known for decades that the persistence of an inflammatory stimulus is responsible for the onset of many diseases. AA is essential to stimulate the immune system by increasing the strength and protection of the organism. Therefore, its immunostimulant, antinflammatory, antiviral and antibacterial roles are well known, we have summarized its main functions in different types of diseases related to the immune system and chronic inflammation. We can conclude that AA, due to its effects and diversity of regulated pathways, is suitable for use in various fields of medicine including immunology, toxicology, radiobiology and others. AA is not preferable to be used as an isolated mode of treatment, but it can be co-applied as an adjuvant to regulate immunity, gene expression and other important physiological processes. However, we propose that future studies will take into consideration the research of new combinations of antioxidant natural substances and drugs.

The best supplements with Ascorbic Acid in Allergy / Immune category:

• Vitamin C with Rose Hips (Rosa Canina), 500 mg, 110 Tablets (21st Century) - Vitamin C is an important antioxidant nutrient that supports the immune system. It contains among others: Ascorbic Acid.
• Abreve, Advanced Immune System Support Formula, 180 Vegetarian Capsules (Zahler) - Powerful Immune System Support. It contains among others: Ascorbic Acid.
• Junior C, Advanced Chewable Vitamin C, Natural Orange Flavor, 250 mg, 180 Tablets (Discontinued Item) (Zahler) - Antioxidant & Immune System BoosterVitamin C is an essential nutrient that functions as a powerful antioxidant. It contains among others: Ascorbic Acid.
• AllergEase, Immune System Support Formula, 90 Vegetable Capsules (Zahler) - Immune System Support FormulaZahler's AllergEase contains a unique combination of herbs and nutrients. It contains among others: Ascorbic Acid.
• Liposomal Vitamin C with Quali-C, 1,000 mg, 180 Vegetarian Capsules (Zenwise Health) - Zenwise Health® Liposomal Vitamin C is an antioxidant supplement that utilizes liposomal technology to ensure bioavailability of Vitamin C (Ascorbic Acid), an essential compound for the body. It contains among others: Ascorbic Acid.
• Green Tea Extract with EGCG + Vitamin C, 120 Vegetarian Capsules (Zenwise Health) - Zenwise Health Green Tea Extract features 725 mg of Green Tea Extract to support weight loss, energy levels, cognition, and cardiovascular health. It contains among others: Ascorbic Acid.
• C-500, 500 mg, 250 Tablets (21st Century) - Vitamin C is an important antioxidant nutrient that helps neutralize free radicals and supports the immune system. It contains among others: Ascorbic Acid.
• C-1000, Prolonged Release, 110 Tablets (21st Century) - Vitamin C is an important antioxidant nutrient that helps neutralize free radicals and supports the immune system. It contains among others: Ascorbic Acid.
• C, 500 mg, 110 Tablets (21st Century) - Vitamin C is an important antioxidant nutrient that supports the immune system. It contains among others: Ascorbic Acid.
• Max Strength Vitamin C + Superior Immune Booster, Orange Blast, 60 Vegan Gummies (Discontinued Item) (Zhou Nutrition) - Vitamin C+ gets an A+ in our book. It contains among others: Ascorbic Acid.
• Vitamin C, 250 mg, 110 Tablets (21st Century) - Vitamin C is an important antioxidant nutrient that supports the immune system. It contains among others: Ascorbic Acid.
• Vitamin C, 1,000 mg, 90 Tablets (Solgar) - Vitamin C is a water-soluble vitamin that helps fight free radicals, which can lead to oxidative stress and the premature aging of cells. It contains among others: Ascorbic Acid.
• Ester-C Plus, Vitamin C, 1,000 mg, 90 Tablets (Solgar) - Ester-C Plus is exclusively formulated by Solgar and provides a patented, pH neutral (non acidic) Vitamin C that is gentle on the stomach. It contains among others: Ascorbic Acid.
• Ester-C Plus, Vitamin C, 500 mg, 100 Vegetable Capsules (Solgar) - Ester-C Plus is exclusively formulated by Solgar and provides a patented, pH neutral (non acidic) Ester-C Vitamin C that is gentle on the stomach. It contains among others: Ascorbic Acid.
• Immunity 911 - Extra Powerful Ingredients for Your Stronger Immunity -

  Immunity 911 - Advanced Immune Boster Formula Your First Line Of Defense Against Infection!

  Viruses are floating all around us, ready to filter into our body any moment completely unnoticed. It contains among others: Ascorbic Acid.
• Immune Defence - Zinc Lozenges with Rosehip and Acerola - Your immune system needs daily support to stay in good form, to be able to fight off any pathogens trying to enter your system and to witstand the impact of stress on your body and mind. It contains among others: Ascorbic Acid.
• Ascorbyl Palmitate, 500 mg, 100 Veg Capsules (Now Foods) - NOW Ascorbyl Palmitate is a highly stable form of Ascorbic Acid, or Vitamin C. It contains among others: Ascorbic Acid.
• Vitamin C Crystals, 3 lbs (1361 g) (Now Foods) - Vitamin C is a water soluble nutrient well known for its vital role in the immune system. It contains among others: Ascorbic Acid.
• C-1000, With 100 mg of Bioflavonoids, 250 Veg Capsules (Now Foods) - Vitamin C is an essential nutrient well known for its vital role in the immune system. It contains among others: Ascorbic Acid.
• Sodium Ascorbate, Powder, 8 oz (227 g) (Now Foods) - Now Sodium Ascorbate Powder is an inexpensive buffered form of Vitamin C and is Pharmaceutical Grade. It contains among others: Ascorbic Acid.
• C-1000, With Rose Hips and Bioflavonoids, 250 Tablets (Now Foods) - Vitamins C is a water soluble nutrient well known for its vital role in the immune system. It contains among others: Ascorbic Acid.
• Vitamin C Crystals, 8 oz (227 g) (Now Foods) - Vitamin C is a water soluble nutrient well known for its vital role in the immune system. It contains among others: Ascorbic Acid.
• C-1000, 100 Tablets (Now Foods) - Vitamin C is a water soluble nutrient well known for its vital role in the immune system. It contains among others: Ascorbic Acid.
• Biotin, 1000 mcg, 100 Capsules (Now Foods) - Biotin is a water-soluble vitamin necessary for normal growth and body function. It contains among others: Ascorbic Acid.
• C-1000, 250 Tablets (Now Foods) - Vitamin C is a water soluble nutrient well known for its vital role in the immune system. It contains among others: Ascorbic Acid.
• Cheers - Vitamin C - The Best, Highly Bioavailable And Natural Vitamin C. It contains among others: Ascorbic Acid.

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