In Vivo Activity of Ajoene Against Rodent Malaria.

Perez Hilda A., De la Rosa M., Apitz Rafael
Antimicrobial agents and chemotherapy, 1994

Abstract

Ajoene (4,5,9-trithiadodeca-1,6,11-triene 9-oxide), a product initially isolated from extracts of garlic (Allium sativum), was tested for its antimalarial activity in vivo in a well-characterized murine model. A single ajoene dose of 50 mg/kg, on the day of infection, suppressed the development of parasitemia; there were no obvious acute toxic effects from the tested dose. The combination of ajoene (50 mg/kg) and chloroquine (4.5 mg/kg), given as a single dose on the day of the infection, completely prevented the subsequent development of parasitemia in treated mice.

The best supplements with Ajoene in Cleansing category:

• Para Axe Plus Cleanse Supplement - Do you have unknown parasites? Let’s face it, parasites are gross. It contains among others: Ajoene.

Articles similar to "In Vivo Activity of Ajoene Against Rodent Malaria."

• The role of Ajoene in Cleansing: Inhibition of Phosphatidylcholine Biosynthesis and Cell Proliferation in Trypanosoma Cruzi by Ajoene, an Antiplatelet Compound Isolated From Garlic. (Ajoene [(E,Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide], a potent antiplatelet compound derived from garlic, inhibits the proliferation of both epimastigotes and amastigotes of Trypanosoma cruzi, the causative agent of Chagas' disease...)
• The impact of Ajoene on Cleansing: Effects of Ajoene on Lymphocyte and Macrophage Membrane-Dependent Functions. (Ajoene, (E, Z) -4, 5, 9-trithiadeca-1, 6, 11-triene 9 oxide, is a compound originally isolated from ethanolic extracts of garlic that impairs platelet aggregation by inhibiting the functional exposure of platelet integrins GPIIb/IIIa...)

Previous article

Inhibitory Effect of Allicin on the Growth of Babesia and Theileria Equi Parasites.

Next article

Inhibition of Phosphatidylcholine Biosynthesis and Cell Proliferation in Trypanosoma Cruzi by Ajoene, an Antiplatelet Compound Isolated From Garlic.