Lotto Valentina, Choi Sang-Woon, Friso Simonetta
British journal of nutrition, 2011
Abstract
The objective of the present review is to highlight the relationship between low vitamin B6 status and CVD through its link with inflammation. While overt vitamin B6 deficiency is uncommon in clinical practice, increasing evidence suggests that marginal vitamin B6 deficiency is rather frequent in a consistent proportion of the population and is related to an increased risk of inflammation-related diseases. Ample evidence substantiates the theory of atherosclerosis as an inflammatory disease, and low plasma vitamin B6 concentrations have been related to increased CVD risk. Several studies have also shown that low vitamin B6 status is associated with rheumatoid arthritis and chronic inflammatory bowel diseases, both of which hold an underlying chronic inflammatory condition. Furthermore, the inverse association observed between inflammation markers and vitamin B6 supports the notion that inflammation may represent the common link between low vitamin B6 status and CVD risk. In addition to the epidemiological evidence, there are a number of cell culture and animal studies that have suggested several possible mechanisms relating impaired vitamin B6 status with chronic inflammation. A mild vitamin B6 deficiency characterises, in most cases, a subclinical at-risk condition in inflammatory-linked diseases which should be addressed by an appropriate individually tailored nutritional preventive or therapeutic strategy.
| PMID: | 21486513 |
|---|---|
| DOI: | 10.1017/S0007114511000407 |
| Category: | Cardiovascular Support |
The best supplements with Pyridoxine in Cardiovascular Support category:
- B-Complex "100", 100 Vegetable Capsules (Solgar) - Each required nutrient in the Vitamin B Complex performs a unique role in maintaining proper metabolic functioning, while nutritionally supporting the body during the occasional stress of daily living. It contains among others: Pyridoxine.
- B-6, 50 mg, 100 Tablets (Now Foods) - Vitamin B6 is a cofactor in numerous enzymatic reactions and is required for the metabolism of fats, carbohydrates, and proteins. It contains among others: Pyridoxine.
- Brain Actives - Brain Actives is a top quality food supplement with ingredients that will bring your brain to its peak performance without causing any harm. It contains among others: Pyridoxine.
- Vitabase - Enfūz (Advanced) - Enfūz Advanced is a complete nutritional supplement program designed to meet your basic nutritional needs. It contains among others: Pyridoxine.
Articles similar to "Vitamin B6: A Challenging Link Between Nutrition and Inflammation in CVD."
- The significance of Pyridoxine for Cardiovascular Support: Vitamin B6 and Cardiovascular Disease. (While overt vitamin B6 deficiency is not a frequent finding nowadays in medical practice, evidence suggests that insufficiency of this vitamin is rather widespread in a quite large portion of the population such as the elderly or in not unusual conditions such as that of alcohol addiction...)
- The role of Pyridoxine in Cardiovascular Support: Dietary Vitamin B 6 Intake Associated With a Decreased Risk of Cardiovascular Disease: A Prospective Cohort Study. (Although the biological mechanisms underlying the beneficial effects of vitamin B6 on cardiovascular disease (CVD) have been reported on, epidemiological studies have yielded controversial results, and data on the Korean population are limited...)
- The significance of Pyridoxine for Cardiovascular Support: Subclinical Inflammation, Telomere Shortening, Homocysteine, Vitamin B6, and Mortality: The Ludwigshafen Risk and Cardiovascular Health Study. (Purpose: Short telomeres and B vitamin deficiencies have been proposed as risk factors for age-related diseases and mortality that interact through oxidative stress and inflammation... In conclusion, hyperhomocysteinemia and vitamin B6 deficiency are risk factors for death from any cause. Hyperhomocysteinemia and vitamin B6 deficiency correlate with increased mortality. This correlation might, at least partially, be explained by accelerated telomere shortening induced by oxidative stress and systemic inflammation in these circumstances. )
Previous article
Vitamin B6 Status, Deficiency and Its Consequences - An Overview.