Piao Fengyuan, et al.
Amino acids, 2018
Abstract
Diets in rats and humans have shown promising results. Taurine improved glucagon activity, promoted glycemic stability, modified glucose levels, successfully addressed hyperglycemia via advanced glycation end-product control, improved insulin secretion and had a beneficial effect on insulin resistance. Taurine treatment performed well against oxidative stress in brain, increased the secretion of required hormones and protected against neuropathy, retinopathy and nephropathy in diabetes compared with the control. Taurine has been observed to be effective in treatments against diabetic hepatotoxicity, vascular problems and heart injury in diabetes. Taurine was shown to be effective against oxidative stress. The mechanism of action of taurine cannot be explained by one pathway, as it has many effects. Several of the pathways are the advanced glycation end-product pathway, PI3-kinase/AKT pathway and mitochondrial apoptosis pathway. The worldwide threat of diabetes underscores the urgent need for novel therapeutic measures against this disorder. Taurine (2-aminoethane sulfonic acid) is a natural compound that has been studied in diabetes and diabetes-induced complications.
Keywords
Diabetes; Nephropathy; Neuropathy; Retinopathy; Taurine
| PMID: | 29492671 |
|---|---|
| Category: | Diabetes / Blood Sugar |
Articles similar to "Ameliorative effects of taurine against diabetes: a review."
- The significance of Taurine for Diabetes / Blood Sugar: Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study. (Taurine, the most abundant, semiessential, sulfur-containing amino acid, is well known to lower blood pressure (BP) in hypertensive animal models...)
- The role of Taurine in Diabetes / Blood Sugar: Protective and therapeutic effectiveness of taurine in diabetes mellitus: a rationale for antioxidant supplementation. (Taurine, 2-amino ethanesulfonic acid, is a conditionally essential β amino acid which is not utilized in protein synthesis...)
Previous article
Next article
Roles of taurine in cognitive function of physiology, pathologies and toxication.