Vitamin B 6: Deficiency diseases and methods of analysis.

Ahmad Iqbal, et al.
Pakistan journal of pharmaceutical sciences, 2013

Abstract

Vitamin B6 (pyridoxine) is closely associated with the functions of the nervous, immune and endocrine systems. It also participates in the metabolic processes of proteins, lipids and carbohydrates. Pyridoxine deficiency may result in neurological disorders including convulsions and epileptic encephalopathy and may lead to infant abnormalities. The Intravenous administration of pyridoxine to patients results in a dramatic cessation of seizures. A number of analytical methods were developed for the determination of pyridoxine in different dosage forms, food materials and biological fluids. These include UV spectrometric, spectrofluorimetric, mass spectrometric, thin-layer and high-performance liquid chromatographic, electrophoretic, electrochemical and enzymatic methods. Most of these methods are capable of determining pyridoxine in the presence of other vitamins and complex systems in µg quantities. The development and applications of these methods in pharmaceutical and clinical analysis mostly during the last decade have been reviewed.

PMID:24035968
Category:Vitamins

The best supplements with Pyridoxine in Vitamins category:

Articles similar to "Vitamin B 6: Deficiency diseases and methods of analysis."

  • The significance of Pyridoxine for Vitamins: Vitamin B6 Status, Deficiency and Its Consequences - An Overview. ( Vitamin B6 is thought to be a most versatile coenzyme that participates in more than 100 biochemical reactions... In fact, it has been proposed that suboptimal vitamin B6 status is associated with certain diseases that particularly afflict the elderly population: impaired cognitive function, Alzheimer's disease, cardiovascular disease, and different types of cancer. Some of these problems may be related to the elevated homocysteine concentrations associated to vitamin B6 deficiency, but there is also evidence for other mechanisms independent of homocysteine by which a suboptimal vitamin B6 status could increase the risk for these chronic diseases.)
  • The impact of Pyridoxine on Vitamins: Vitamin B6 Deficiency: A Potential Cause of Refractory Seizures in Adults. (Objective: In children, vitamin B(6) (pyridoxine) deficiency has been described as a cause of seizures that are refractory to conventional antiepileptic medications... Although refractory seizures caused by vitamin B(6) deficiency are rare in adults, it should be considered in critically ill adult patients with refractory seizures.)
  • The significance of Pyridoxine for Vitamins: Vitamin B6 Deficiency, Genome Instability and Cancer. (Vitamin B6 functions as a coenzyme in >140 enzymatic reactions involved in the metabolism of amino acids, carbohydrates, neurotransmitters, and lipids... Although refractory seizures caused by vitamin B(6) deficiency are rare in adults, it should be considered in critically ill adult patients with refractory seizures.)

Previous article

Low vitamin intake is associated with risk of frailty in older adults.

Next article

Vitamin B12 deficiency – A 21st century perspective.