Imagawa Atsushi, et al.
Digestive diseases and sciences, 2012
Abstract
Background
Although hyoscine butyl bromide (HB) and glucagon (GL) are often used as antispasmodic drugs during esophagogastroduodenoscopy (EGD), these agents may cause adverse effects. Recently, it was reported that peppermint oil solution (PO) was very effective and had few side effects.
Aim
We clarified the efficacy and usefulness of PO as an antispasmodic during upper endoscopy, especially for elderly patients.
Methods
This study was a non-randomized prospective study. The antispasmodic score (1-5, where 5 represents no spasm) was defined according to the degree of spasms of the antrum and difficulty of biopsy. We compared the antispasmodic scores between non-elderly patients (younger than 70) and elderly patients (70 years old or older) according to the antispasmodic agent.
Results
A total of 8,269 (Group PO: HB: GL: NO (no antispasmodic) = 1,893: 6,063: 157: 156) EGD procedures were performed. There was no significant difference in the antispasmodic score between Group PO (mean score ± standard deviation: 4.025 ± 0.925) and Group HB (4.063 ± 0.887). Among the non-elderly patients, those in Group PO (n = 599, 3.923 ± 0.935) had a worse antispasmodic score than those in Group HB (n = 4,583, 4.062 ± 0.876, P < 0.001). However, among the elderly patients, those in Group PO (n = 1,294, 4.073 ± 0.917) had similar scores to those in Group HB (n = 1,480, 4.064 ± 0.921, P = 0.83), and significantly better scores than those in Group GL (n = 69, 3.797 ± 0.933, P < 0.05).
Conclusion
Peppermint oil was useful as an antispasmodic during EGD, especially for elderly patients.
PMID: | 22562537 |
---|---|
Category: | General properties of Mentha X Piperita |
Articles similar to "Peppermint oil solution is useful as an antispasmodic drug for esophagogastroduodenoscopy, especially for elderly patients."
- The properties of Mentha X Piperita: Peppermint oil (Kligler, Chaudhary) (Peppermint leaf and peppermint oil have a long history of use for digestive disorders...)
- The properties of Mentha X Piperita: Mentha piperita (peppermint). (PEPPERMINT (Mentha piperita) is a popular herb that can be used in numerous forms (ie, oil, leaf, leaf extract, and leaf water)...)
- The properties of Mentha X Piperita: African peppermint (Mentha piperita) from Morocco: Chemical composition and antimicrobial properties of essential oil. (To replace and avoid synthetic chemicals toxicity, there is a growing interest in the investigation of natural products from plant origin for the discovery of active compounds with antimicrobial properties...)
- The properties of Mentha X Piperita: Final report on the safety assessment of Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Leaf Extract, Mentha Piperita (Peppermint) Leaf, and Mentha Piperita (Peppermint) Leaf Water. (Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Leaf Extract, Mentha Piperita (Peppermint) Leaf, Mentha Piperita (Peppermint) Leaf Water are obtained from the Mentha piperita plant...)
- The properties of Mentha X Piperita: A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.). (Peppermint (Mentha piperita L...)
Previous article
The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome.