Piperinox

Piperinox – Ingredientes

• Guarana Seed Extract [22% Caffeine] (Paullinia Cupana)
  • Extrato de sementes de guaraná (Paullinia Cupana)
    Tem um efeito estimulante. Apoia o metabolismo de lípidos. Species: Paullinia Cupana,
    Family: Sapindaceae,
    European Medicines Agency: EMA: Paulliniae Semen,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH29CF20,
    References:
    Weight Loss: ALKHATIB, Ahmad; SEIJO, M.; LARUMBE, E.; NACLERIO, F. Acute effectiveness of a “fat-loss” product on substrate utilization, perception of hunger, mood state and rate of perceived exertion at rest and during exercise. Journal of the International Society of Sports Nutrition, 2015, 12.1: 44. PMID:26612980.
    
    
  • Cafeína (C₈H₁₀N₄O₂)
    Cafeína aumenta energia instantaneamente, aumenta a concentração e melhora a resistência. Permite a pratica prolongada de exercícios e ajuda a obter melhores resultados.
    Cafeína: Caffeine, 1,3,7-Trimethylxanthine, Thein,
    PubChem CID: 2519,
    Chemical Abstracts Service: CAS: 58-08-2,
    ChemIDplus: 58-08-2,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: N06BC01,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2C8E40,
    References:
    Weight Loss: TABRIZI, R.; SANEEI, P.; LANKARANI, K. B.; AKBARI, M.; KOLAHDOOZ, F.; ESMAILLZADEH, A.; NADI-RAVANDI, S.; MAZOOCHI, M.; ASEMI, Z. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials. Critical reviews in food science and nutrition, 2018, 2018: 1-9. PMID:30335479, SMITH, Andrew Effects of caffeine on human behavior. Food and chemical toxicology, 2002, 40.9: 1243-1255. PMID:12204388.
    
• Cinnamon Bark Extract (Cinnamomum Cassia)
  • Chinese Cinnamon (Cinnamomum Cassia)
    Extrato de casca de canela: ajuda a manter um nível saudável de açúcar no sangue, facilita controlar o peso corporal, melhora o conforto digestivo. Species: Cinnamomum Cassia,
    Family: Lauraceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IHAA97E0,
    References:
    Weight Loss: ABDALI, Daniyal; SAMSON, Sue E.; GROVER, Ashok Kumar How Effective Are Antioxidant Supplements in Obesity and Diabetes?. Medical Principles and Practice, 2015, 24.3: 201-215. PMID:25791371.
    
    
• Bitter Orange Fruit Extract [6% Synephrine] (Citrus Aurantium)
  • Extrato de frutos de laranja amarga (Citrus Aurantium)
    Extrato de frutos de laranja amarga: facilita controlar o peso corporal, apoia o metabolismo de gordura e hidratos de carbono. Auxilia o trabalho do sistema digestivo. Suprime instantaneamente o apetite, estabilizando o nível de glicose no sangue e aumenta o metabolismo da gordura. Species: Citrus Aurantium,
    Family: Rutaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2932E0,
    References:
    Weight Loss: PREUSS, Harry G.; DIFERDINANDO, D.; BAGCHI, D. Citrus aurantium as a thermogenic, weight-reduction replacement for ephedra: an overview. Journal of medicine, 2002, 33.1-4: 247-264. PMID:12939122, COLKER, Carlon M.; DIFERDINANDO, D.; BAGCHI, D. Effects of Citrus aurantium extract, caffeine, and St. John’s wort on body fat loss, lipid levels, and mood states in overweight healthy adults. Current Therapeutic Research, 1999, 60.3: 145-153..
    
    
  • Sinefrina (C₉H₁₃NO₂)
    Sinefrina: Synephrine, Oxedrine, P-Synephrine, Parasympatol,
    PubChem CID: 7172,
    Chemical Abstracts Service: CAS: 94-07-5,
    ChemIDplus: 94-07-5,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: C01CA08,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS37FFF0,
    References:
    Weight Loss: STOHS, Sidney J.; PREUSS, H. G.; SHARA, M. A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine. International journal of medical sciences, 2012, 9.7: 527. PMID:22991491, STOHS, Sidney J. Efficacy, and Mechanistic Studies Regarding Citrus aurantium (Bitter Orange) Extract and p‐Synephrine. Phytotherapy research, 2017, 31.10: 1463-1474. PMID:28752649.
    
• Ginger Rhizomes Extract [5% Gingerols] (Zingiber Officinale)
  • Extrato de rizoma de gengibre (Zingiber Officinale)
    O extrato de raiz de gengibre reduz o apetite, estimula a produção dos sucos gástricos e alivia os efeitos de várias doenças gastrointestinais (acelera o metabolismo, previne o ganho de peso subsequente). Extrato de rizoma de gengibre: apoia o funcionamento do sistema imunológico, apresenta propriedades antioxidantes, ajuda na absorção de nutrientes, diminui o nível de açúcar no sangue, apoia o metabolismo de hidratos de carbono. Contém aminoácidos essenciais que não são auto-sintetizados no corpo. Fortalece a termogênese, ajudando a queimar as calorias armazenadas. Species: Zingiber Officinale,
    Family: Zingiberaceae,
    European Medicines Agency: EMA: Zingiberis Rhizoma,
    Domain: Plantae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2959F0,
    References:
    Weight Loss: MAHARLOUEI, Najmeh; TABRIZI, R.; LANKARANI, K. B.; REZAIANZADEH, A.; AKBARI, M.; KOLAHDOOZ, F.; RAHIMI, M.; KENESHLOU, F.; ASEMI, Z. The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: A systematic review and meta-analysis of randomized controlled trials. Critical reviews in food science and nutrition, 2018, 2018: 1-14. PMID:29393665, TAGHIZADEH, Mohsen; FARZIN, N.; TAHERI, S.; MAHLOUJI, M.; AKBARI, H.; KARAMALI, F.; ASEMI, Z. The effect of dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles in overweight women: A randomized double-blind placebo-controlled clinical trial. Annals of Nutrition and Metabolism, 2017, 70.4: 277-285. PMID:28595182.
    
    
  • Gingerol (C₁₇H₂₆O₄)
    Gingerol: Gingerol, 6-Gingerol,
    PubChem CID: 442793,
    Chemical Abstracts Service: CAS: 23513-14-6,
    ChemIDplus: 23513-14-6,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 925QK2Z900,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS37D8E0.
    
• Cayenne Pepper Fruit Extract [10% Capsaicin] (Capsicum Annuum L.)
  • Extrato de frutos de Capsicum annuum (pimenta-caiena) (Capsicum Annuum)
    Extrato de frutos de Capsicum annuum (pimenta-caiena): apresenta efeitos benéficos à redução do peso corporal, protege o estômago no caso de contacto com substâncias com propriedades irritantes. Extrato de páprica auxilia o trabalho do sistema digestivo, protegendo o estomago. Ativa a queima de gordura. Species: Capsicum Annuum,
    Family: Solanaceae,
    European Medicines Agency: EMA: Capsici Fructus,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH298100,
    References:
    Weight Loss: WHITING, Stephen; DERBYSHIRE, Emma; TIWARI, B. K. Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Appetite, 2012, 59.2: 341-348. PMID:22634197, VARGHESE, Sharon; et al. Chili pepper as a body weight-loss food. International journal of food sciences and nutrition, 2017, 68.4: 392-401. PMID:27899046.
    
    
  • Capsaicin (C₁₈H₂₇NO₃)
    Capsaicin: Capsaicin, Zostrix, Capsaicine, Transacin,
    PubChem CID: 1548943,
    Chemical Abstracts Service: CAS: 404-86-4,
    ChemIDplus: 404-86-4,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: M02AB01,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS39FBC0,
    References:
    Weight Loss: WHITING, Stephen; DERBYSHIRE, Emma; TIWARI, B. K. Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Appetite, 2012, 59.2: 341-348. PMID:22634197, TAGHIZADEH, Mohsen; FARZIN, N.; TAHERI, S.; MAHLOUJI, M.; AKBARI, H.; KARAMALI, F.; ASEMI, Z. The effect of dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles in overweight women: A randomized double-blind placebo-controlled clinical trial. Annals of Nutrition and Metabolism, 2017, 70.4: 277-285. PMID:28595182.
    
• Black Pepper Fruit Extract – BioPerine® [95% Piperine] (Piper Nigrum L.)
  • BioPerine®
    O BioPerine® é uma forma inovadora da piperina, livre de substâncias químicas utilizadas para cultivo de plantas, tais como adubos, concentrados, fortificantes, pesticidas ou outros produtos de proteção de plantas. A sua segurança de uso foi comprovada pelos estudos da Autoridade Europeia para a Segurança dos Alimentos (EFSA). Graças à melhor, em comparação com o estado convencional, absorção e uso desta forma, observa-se um aumento significativo de absorção de outros ingredientes valiosos deste suplemento. Isso faz com que haja até 30 vezes maiores efeitos do seu funcionamento. Além disso, o BioPerine® contém mais piperina do que extrato de pimenta preta, o que adicionalmente intensifica a eficácia do produto.
    BioPerine®: BioPerine®,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS28E4C0.
    
  • Black Pepper (Piper Nigrum)
    Extrato de pimenta-preta – ajuda na secreção de sucos digestivos, aumenta a absorção de nutrientes e regula os movimentos intestinais. Species: Piper Nigrum,
    Family: Piperaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2CB550,
    References:
    Weight Loss: TAKOOREE, Heerasing; AUMEERUDDY, M. Z.; RENGASAMY, K. R. R.; VENUGOPALA, K. N.; JEEWON, R.; ZENGIN, G.; MAHOMOODALLY, M. F. A systematic review on black pepper (Piper nigrum L.): from folk uses to pharmacological applications. Critical reviews in food science and nutrition, 2019, 2019: 1-34. PMID:30740986, MUJUMDAR, Arvind Manohar; DHULEY, Jayant Nilkanth; DESHMUKH, Vinaykumar Keshav; RAMAN, Palghat Hariharan; NAIK, Suresh Ramnath Anti-inflammatory activity of piperine. Japanese Journal of Medical Science and Biology, 1990, 43.3: 95-100. PMID:2283727.
    
    
  • Piperine (C₁₇H₁₉NO₃)
    Piperine: Piperine, Bioperine, Piperin, 1-Piperoylpiperidine, Piperoylpiperidine, 1-Piperylpiperidine,
    PubChem CID: 638024,
    Chemical Abstracts Service: CAS: 94-62-2,
    ChemIDplus: 94-62-2,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS395F80,
    References:
    Weight Loss: NOGARA, Leonardo; et al. Piperine’s mitigation of obesity and diabetes can be explained by its up-regulation of the metabolic rate of resting muscle. Proceedings of the National Academy of Sciences, 2016, 113.46: 13009-13014. PMID:27799519.
    
• Cromo (picolinato de crômio) (C₁₈H₁₂CrN₃O₆)
  Auxilia a reduzir a fome durante o dia. Graças a estabilização de açúcar no sangue, suprime o apetite. Auxilia no metabolismo dos macro-nutrientes.
  Cromo (picolinato de crômio): Chromium Picolinate, Picolinic Acid Chromium(III) Salt, Chromium(III) Picolinate,
  PubChem CID: 151932,
  Chemical Abstracts Service: CAS: 14639-25-9,
  ChemIDplus: 14639-25-9,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS29A810-1,
  References:
  Weight Loss: PITTLER, M. H.; STEVINSON, C.; ERNST, E. Chromium picolinate for reducing body weight: meta-analysis of randomized trials. International journal of obesity, 2003, 27.4: 522. PMID:12664086, DOCHERTY, John P.; SACK, D. A.; ROFFMAN, M.; FINCH, M.; KOMOROWSKI, J. R. A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving. Journal of Psychiatric Practice®, 2005, 11.5: 302-314. PMID:16184071.
  

Recommended intake of this supplement: 1 capsule, daily (adults).