Piperinox

Piperinox – Ingrediente

• Guarana Seed Extract [22% Caffeine] (Paullinia Cupana)
  • Extractul din semințe de guarana (Paullinia Cupana)
    Are efect stimulant. Ajută la metabolizarea lipidelor. Species: Paullinia Cupana,
    Family: Sapindaceae,
    European Medicines Agency: EMA: Paulliniae Semen,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH29CF20,
    References:
    Weight Loss: ALKHATIB, Ahmad; SEIJO, M.; LARUMBE, E.; NACLERIO, F. Acute effectiveness of a “fat-loss” product on substrate utilization, perception of hunger, mood state and rate of perceived exertion at rest and during exercise. Journal of the International Society of Sports Nutrition, 2015, 12.1: 44. PMID:26612980.
    
    
  • Cafeină (C₈H₁₀N₄O₂)
    Cafeină anhidră naturală – crește concentrarea și rezistența, reducând, de asemenea, oboseala după activitatea fizică.
    Cafeină: Caffeine, 1,3,7-Trimethylxanthine, Thein,
    PubChem CID: 2519,
    Chemical Abstracts Service: CAS: 58-08-2,
    ChemIDplus: 58-08-2,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: N06BC01,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2C8E40,
    References:
    Weight Loss: TABRIZI, R.; SANEEI, P.; LANKARANI, K. B.; AKBARI, M.; KOLAHDOOZ, F.; ESMAILLZADEH, A.; NADI-RAVANDI, S.; MAZOOCHI, M.; ASEMI, Z. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials. Critical reviews in food science and nutrition, 2018, 2018: 1-9. PMID:30335479, SMITH, Andrew Effects of caffeine on human behavior. Food and chemical toxicology, 2002, 40.9: 1243-1255. PMID:12204388.
    
• Cinnamon Bark Extract (Cinnamomum Cassia)
  • Chinese Cinnamon (Cinnamomum Cassia)
    Extractul din scorțișoară: ajută la menținerea nivelului adecvat de zahăr în sânge, facilitează controlarea masei corporale, îmbunătățește funcționarea întregului sistemul digestiv. Species: Cinnamomum Cassia,
    Family: Lauraceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IHAA97E0,
    References:
    Weight Loss: ABDALI, Daniyal; SAMSON, Sue E.; GROVER, Ashok Kumar How Effective Are Antioxidant Supplements in Obesity and Diabetes?. Medical Principles and Practice, 2015, 24.3: 201-215. PMID:25791371.
    
    
• Bitter Orange Fruit Extract [6% Synephrine] (Citrus Aurantium)
  • Extractul din fructe de portocală amară (Citrus Aurantium)
    Extractul din fructe de portocală amară: facilitează controlarea masei corporale, îmbunătățește metabolizarea grăsimilor și hidrocarburilor. Extract de fructe de portocal amar – favorizează metabolismul lipidic și controlul greutății. Utilizarea acestuia are impact asupra funcției sistemului digestiv. Species: Citrus Aurantium,
    Family: Rutaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2932E0,
    References:
    Weight Loss: PREUSS, Harry G.; DIFERDINANDO, D.; BAGCHI, D. Citrus aurantium as a thermogenic, weight-reduction replacement for ephedra: an overview. Journal of medicine, 2002, 33.1-4: 247-264. PMID:12939122, COLKER, Carlon M.; DIFERDINANDO, D.; BAGCHI, D. Effects of Citrus aurantium extract, caffeine, and St. John’s wort on body fat loss, lipid levels, and mood states in overweight healthy adults. Current Therapeutic Research, 1999, 60.3: 145-153..
    
    
  • Synephrine (C₉H₁₃NO₂)
    Synephrine: Synephrine, Oxedrine, P-Synephrine, Parasympatol,
    PubChem CID: 7172,
    Chemical Abstracts Service: CAS: 94-07-5,
    ChemIDplus: 94-07-5,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: C01CA08,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS37FFF0,
    References:
    Weight Loss: STOHS, Sidney J.; PREUSS, H. G.; SHARA, M. A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine. International journal of medical sciences, 2012, 9.7: 527. PMID:22991491, STOHS, Sidney J. Efficacy, and Mechanistic Studies Regarding Citrus aurantium (Bitter Orange) Extract and p‐Synephrine. Phytotherapy research, 2017, 31.10: 1463-1474. PMID:28752649.
    
• Ginger Rhizomes Extract [5% Gingerols] (Zingiber Officinale)
  • Extractul din ghimbir medicinal (Zingiber Officinale)
    Extract de rădăcină de ghimbir reduce pofta de mâncare, stimulează producerea de suc gastric, facilitează cursul unor boli ale tractului gastrointestinal (stimulează metabolismul, previne creșterea repetată a greutății). Extractul din ghimbir medicinal: ajută la funcționarea sistemului imunitar, are o acțiune antioxidantă, ajută la asimilarea substanțelor nutritive, scade nivelul de zahăr din sânge, îmbunătățește metabolizarea hidrocarburilor. Contine aminoacizi esențiali care nu sunt sintetizate de catre organism Îmbunătățește termogeneza, ajutând arderea caloriilor stocate. Species: Zingiber Officinale,
    Family: Zingiberaceae,
    European Medicines Agency: EMA: Zingiberis Rhizoma,
    Domain: Plantae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2959F0,
    References:
    Weight Loss: MAHARLOUEI, Najmeh; TABRIZI, R.; LANKARANI, K. B.; REZAIANZADEH, A.; AKBARI, M.; KOLAHDOOZ, F.; RAHIMI, M.; KENESHLOU, F.; ASEMI, Z. The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: A systematic review and meta-analysis of randomized controlled trials. Critical reviews in food science and nutrition, 2018, 2018: 1-14. PMID:29393665, TAGHIZADEH, Mohsen; FARZIN, N.; TAHERI, S.; MAHLOUJI, M.; AKBARI, H.; KARAMALI, F.; ASEMI, Z. The effect of dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles in overweight women: A randomized double-blind placebo-controlled clinical trial. Annals of Nutrition and Metabolism, 2017, 70.4: 277-285. PMID:28595182.
    
    
  • Gingerol (C₁₇H₂₆O₄)
    Gingerol: Gingerol, 6-Gingerol,
    PubChem CID: 442793,
    Chemical Abstracts Service: CAS: 23513-14-6,
    ChemIDplus: 23513-14-6,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 925QK2Z900,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS37D8E0.
    
• Cayenne Pepper Fruit Extract [10% Capsaicin] (Capsicum Annuum L.)
  • Extractul din ardei iute (piper de Cayene) (Capsicum Annuum)
    Extractul din ardei iute (piper de Cayene): are un efect benefic asupra reducerii masei corporale, protejează stomacul împotriva contactului cu substanțele iritante. Extract de Capsicum – permite gestionarea greutății și oferă un echilibru ideal pentru sistemul digestiv. Species: Capsicum Annuum,
    Family: Solanaceae,
    European Medicines Agency: EMA: Capsici Fructus,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH298100,
    References:
    Weight Loss: WHITING, Stephen; DERBYSHIRE, Emma; TIWARI, B. K. Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Appetite, 2012, 59.2: 341-348. PMID:22634197, VARGHESE, Sharon; et al. Chili pepper as a body weight-loss food. International journal of food sciences and nutrition, 2017, 68.4: 392-401. PMID:27899046.
    
    
  • Capsaicin (C₁₈H₂₇NO₃)
    Capsaicin: Capsaicin, Zostrix, Capsaicine, Transacin,
    PubChem CID: 1548943,
    Chemical Abstracts Service: CAS: 404-86-4,
    ChemIDplus: 404-86-4,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: M02AB01,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS39FBC0,
    References:
    Weight Loss: WHITING, Stephen; DERBYSHIRE, Emma; TIWARI, B. K. Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Appetite, 2012, 59.2: 341-348. PMID:22634197, TAGHIZADEH, Mohsen; FARZIN, N.; TAHERI, S.; MAHLOUJI, M.; AKBARI, H.; KARAMALI, F.; ASEMI, Z. The effect of dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles in overweight women: A randomized double-blind placebo-controlled clinical trial. Annals of Nutrition and Metabolism, 2017, 70.4: 277-285. PMID:28595182.
    
• Black Pepper Fruit Extract – BioPerine® [95% Piperine] (Piper Nigrum L.)
  • BioPerine®
    BioPerine® este o formă inovativă a piperinei, fără substanțe chimice utilizate la cultivarea plantelor – adică îngrășăminte, concentrați, suplimente, pesticide sau alte preparate pentru protejarea plantelor. Siguranța acestui produs a fost confirmată prin testele efectuate de către Autoritatea Europeană pentru Siguranța Alimentară (EFSA). Datorită absorbției optimizate față de starea convențională a piperinei, se observă o asimilare mult mai bună a componentelor acestui supliment. Efectul acestei substanțe este chiar și de până la 30 de ori mai puternic. În plus, preparatul BioPerine® conține mai multă piperină decât extractul din piper negru, ceea ce intensifică rezultatele utilizării produsului.
    BioPerine®: BioPerine®,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS28E4C0.
    
  • Black Pepper (Piper Nigrum)
    Extract de fructe de piper negru – susține secreția de sucuri digestive, crește absorbția de nutrienți, reglează tranzitul intestinal. Species: Piper Nigrum,
    Family: Piperaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2CB550,
    References:
    Weight Loss: TAKOOREE, Heerasing; AUMEERUDDY, M. Z.; RENGASAMY, K. R. R.; VENUGOPALA, K. N.; JEEWON, R.; ZENGIN, G.; MAHOMOODALLY, M. F. A systematic review on black pepper (Piper nigrum L.): from folk uses to pharmacological applications. Critical reviews in food science and nutrition, 2019, 2019: 1-34. PMID:30740986, MUJUMDAR, Arvind Manohar; DHULEY, Jayant Nilkanth; DESHMUKH, Vinaykumar Keshav; RAMAN, Palghat Hariharan; NAIK, Suresh Ramnath Anti-inflammatory activity of piperine. Japanese Journal of Medical Science and Biology, 1990, 43.3: 95-100. PMID:2283727.
    
    
  • Piperine (C₁₇H₁₉NO₃)
    Piperine: Piperine, Bioperine, Piperin, 1-Piperoylpiperidine, Piperoylpiperidine, 1-Piperylpiperidine,
    PubChem CID: 638024,
    Chemical Abstracts Service: CAS: 94-62-2,
    ChemIDplus: 94-62-2,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS395F80,
    References:
    Weight Loss: NOGARA, Leonardo; et al. Piperine’s mitigation of obesity and diabetes can be explained by its up-regulation of the metabolic rate of resting muscle. Proceedings of the National Academy of Sciences, 2016, 113.46: 13009-13014. PMID:27799519.
    
• Cromul (Crom picolinat) (C₁₈H₁₂CrN₃O₆)
  Crom – menține nivelurile normale ale glicemiei, afectează metabolismul macronutrienților.
  Cromul (Crom picolinat): Chromium Picolinate, Picolinic Acid Chromium(III) Salt, Chromium(III) Picolinate,
  PubChem CID: 151932,
  Chemical Abstracts Service: CAS: 14639-25-9,
  ChemIDplus: 14639-25-9,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS29A810-1,
  References:
  Weight Loss: PITTLER, M. H.; STEVINSON, C.; ERNST, E. Chromium picolinate for reducing body weight: meta-analysis of randomized trials. International journal of obesity, 2003, 27.4: 522. PMID:12664086, DOCHERTY, John P.; SACK, D. A.; ROFFMAN, M.; FINCH, M.; KOMOROWSKI, J. R. A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving. Journal of Psychiatric Practice®, 2005, 11.5: 302-314. PMID:16184071.
  

Recommended intake of this supplement: 1 capsule, daily (adults).