Phen24

Phen24 – Ingredients

• Day Ingredients
  
• Guarana Seed (Paullinia Cupana)
  A popular energy supplement, Guarana Extract offers one of the highest concentrations of caffeine among any plant. In fact, it can contain up to 3.6 to 5.8% caffeine by weight whereas coffee has only up to 2%. It has a stimulating effect. Supports lipid metabolism. Species: Paullinia Cupana,
  Family: Sapindaceae,
  European Medicines Agency: EMA: Paulliniae Semen,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH29CF20,
  References:
  Weight Loss: ALKHATIB, Ahmad; SEIJO, M.; LARUMBE, E.; NACLERIO, F. Acute effectiveness of a “fat-loss” product on substrate utilization, perception of hunger, mood state and rate of perceived exertion at rest and during exercise. Journal of the International Society of Sports Nutrition, 2015, 12.1: 44. PMID:26612980.
  
  
  • Caffeine (C₈H₁₀N₄O₂)
    Caffeine isn’t just a great ingredient to reduce fatigue and increase alertness and focus (as would your favorite cup of coffee). It also stimulates thermogenesis, slimming you down by turning up your body’s internal temperature. It can even reduce your appetite, helping you stay on track with your healthy eating choices. Caffeine instantly energizes, increases concentration and improves endurance. It allows you to practice longer and achieve better results.
    Caffeine: Caffeine, 1,3,7-Trimethylxanthine, Thein,
    PubChem CID: 2519,
    Chemical Abstracts Service: CAS: 58-08-2,
    ChemIDplus: 58-08-2,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: N06BC01,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2C8E40,
    References:
    Weight Loss: TABRIZI, R.; SANEEI, P.; LANKARANI, K. B.; AKBARI, M.; KOLAHDOOZ, F.; ESMAILLZADEH, A.; NADI-RAVANDI, S.; MAZOOCHI, M.; ASEMI, Z. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials. Critical reviews in food science and nutrition, 2018, 2018: 1-9. PMID:30335479, SMITH, Andrew Effects of caffeine on human behavior. Food and chemical toxicology, 2002, 40.9: 1243-1255. PMID:12204388.
    
• Cayenne Pepper (Capsicum Annuum)
  Cayenne powder isn’t just an ingredient for your favorite dishes. Spicy food increases your body temperature, forcing the body to expend energy (calories) to cool down. Consumed daily, Cayenne powder can increase metabolic rates by up to 25%. Cayenne Pepper Fruit Extract: has a positive impact on weight reduction, protects the stomach in case of contact with corrosive substances. Capsicum annuum extract supports the work of the digestive system, shielding the stomach. Activates fat reserves burning. Species: Capsicum Annuum,
  Family: Solanaceae,
  European Medicines Agency: EMA: Capsici Fructus,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH298100,
  References:
  Weight Loss: WHITING, Stephen; DERBYSHIRE, Emma; TIWARI, B. K. Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Appetite, 2012, 59.2: 341-348. PMID:22634197, VARGHESE, Sharon; et al. Chili pepper as a body weight-loss food. International journal of food sciences and nutrition, 2017, 68.4: 392-401. PMID:27899046.
  
  
• Phenylalanine (C₉H₁₁NO₂)
  Phenylalanine is an essential amino acid that suppresses your appetite by stimulating the release of cholecystokinin, an intestinal hormone. Once released, cholecystokinin sends a signal to your brain to feel satiated after eating. By helping you feel more full, phenylalanine can effectively prevent overeating.
  Phenylalanine: Phenylalanine, L-Phenylalanine, (S)-2-Amino-3-Phenylpropanoic Acid, 3-Phenyl-L-Alanine,
  PubChem CID: 6140,
  Chemical Abstracts Service: CAS: 63-91-2,
  ChemIDplus: 63-91-2,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: 47E5O17Y3R,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS320C80.
  
• Iodine (I₂)
  There is a complex relationship between your weight, thyroid, and metabolism. After all, the hormones secreted by the thyroid gland directly regulate your metabolism. Increasing your iodine intake can improve your thyroid function, which in turn, can boost your metabolism, helping you lose weight.
  Iodine: Iodine, PubChem CID: 807, Chemical Abstracts Service: CAS: 7553-56-2, ChemIDplus: 7553-56-2, WHO Anatomical Therapeutic Chemical Classification System: ATC code: D08AG03, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS323390, References: Weight Loss: PAUL, T.; MEYERS, B.; WITORSCH, R.J.; PINO, S.; CHIPKIN, S.; INGBAR, S. H.; BRAVERMAN, L. E. The effect of small increases in dietary iodine on thyroid function in euthyroid subjects. Metabolism, 1988, 37.2: 121-124. PMID:3340004.
  
• Manganese (Mn)
  Manganese helps control your body’s ability to metabolize fats and carbohydrates. It also helps prevent food cravings by regulating regulating your blood sugar. By assisting in proper thyroid functioning, it helps maintain a healthy metabolism, and because it also helps your body absorb calcium, it reinforces bone metabolism and healthy bone structure too.
  Manganese: Manganese, PubChem CID: 23930, Chemical Abstracts Service: CAS: 7439-96-5, ChemIDplus: 7439-96-5, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS325AA0, References: Weight Loss: YANG, Qing Gain weight by “going diet?” Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010. The Yale journal of biology and medicine, 2010, 83.2: 101. PMID:20589192.
  
• Zinc (Zn)
  Zinc: Zinc, PubChem CID: 23994, Chemical Abstracts Service: CAS: 7440-66-6, ChemIDplus: 7440-66-6, WHO Anatomical Therapeutic Chemical Classification System: ATC code: A16AX05, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS26E8F0, References: Weight Loss: ABDALI, Daniyal; SAMSON, Sue E.; GROVER, Ashok Kumar How Effective Are Antioxidant Supplements in Obesity and Diabetes?. Medical Principles and Practice, 2015, 24.3: 201-215. PMID:25791371.
  
  • Zinc (Zinc Citrate) (C₁₂H₁₀O₁₄Zn₃)
    Zinc Citrate works with vitamins A and E to manufacture the hormones secreted by your thyroid gland. When combined with vitamin B6, zinc also aids in the production of pancreatic enzymes which enable your body to digest food. Proper digestion helps your body break down food more efficiently, preventing the likelihood of it being stored as fat.
    Zinc (Zinc Citrate): Zinc Citrate, Trizinc Dicitrate, Citric Acid,
    PubChem CID: 11023,
    Chemical Abstracts Service: CAS: 546-46-3,
    ChemIDplus: 546-46-3,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: K72I3DEX9B,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS26E8F0-1.
    
• Copper (Cu)
  Copper plays an essential role in the numerous oxidative reactions that help your body convert fats and fatty tissue into energy.
  Copper: Copper, PubChem CID: 23978, Chemical Abstracts Service: CAS: 7440-50-8, ChemIDplus: 7440-50-8, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2A9270.
  
  • Copper (cupric sulfate) (CuSO₄ or CuO₄S)
    
    Copper (cupric sulfate): Cupric Sulfate, Copper Sulphate, Copper Sulfate, Copper(II) Sulfate, Cupric Sulfate Anhydrous, Blue Stone, Copper Monosulfate, Hylinec, Trinagle, Delcup,
    PubChem CID: 24462,
    Chemical Abstracts Service: CAS: 7758-98-7,
    ChemIDplus: 7758-98-7,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: V03AB20,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2A9270-2.
    
• Night Ingredients
  
• Konjac Glucomannan (Amorphophallus Konjac)
  Glucomannan is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). As a dietary fiber, Glucomannan absorbs water and maintains a feeling of satiation, effectively reducing cravings. It means you’ll be less likely to eat later in the evening, keeping the cravings that can compromise your diet at bay. Species: Amorphophallus Konjac,
  Family: Araceae,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IHCEE8C0,
  References:
  Weight Loss: KAATS, Gilbert R.; BAGCHI, Debasis; PREUSS, Harry G. Konjac glucomannan dietary supplementation causes significant fat loss in compliant overweight adults. Journal of the American College of Nutrition, 2015, 2015: 1-7. PMID:26492494, MAIA-LANDIM, Andrea; et al. Long-term effects of Garcinia cambogia/Glucomannan on weight loss in people with obesity, PLIN4, FTO and Trp64Arg polymorphisms. BMC complementary and alternative medicine, 2018, 18.1: 26. PMID:29361938.
  
  
  • Glucomannan (C₂₄H₄₂O₂₁)
    Glucomannan, a fiber that may help reduce blood sugar and insulin spikes as well as decrease hunger and help with elimination.
    Glucomannan: Glucomannan, KONJAC MANNAN, Glucomannoglycan, (Glucomannan)n, (Glucomannan)n+1, (1-6)-Alpha-Glucomannan,
    PubChem CID: 24892726,
    Chemical Abstracts Service: CAS: 37220-17-0,
    ChemIDplus: 37220-17-0,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 36W3E5TAMG,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2B55C0.
    
• Green Tea (Camellia Sinensis)
  Fat can’t be burned until it’s broken down in your fat cells and moved to your bloodstream, but the compounds in green tea can boost your fat burning hormones.Norepinephrine is a chemical that instructs fat cells to break down fat. EGCG, the main antioxidant found in green tea, inhibits an enzyme responsible for breaking down norepinephrine. This results in an increase in norepinephrine, which can increase the amount of fat your body breaks down.It is even thought that caffeine and EGCG, both of which occur naturally in green tea, work together because caffeine works to the same effect as EGCG. Green tea extract stimulates the oxidation of fatty acids, supports thermogenesis of the body, and is a powerful antioxidant that protects against the negative effects of free radicals. Green tea is generally beneficial in supporting a healthy metabolism and your overall health. Species: Camellia Sinensis,
  Family: Theaceae,
  European Medicines Agency: EMA: Camelliae Sinensis Non Fermentatum Folium,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2B07A0,
  References:
  Weight Loss: MAKI, Kevin C.; REEVES, M. S.; FARMER, M.; YASUNAGA, K.; MATSUO, N.; KATSURAGI, Y.; KOMIKADO, M.; TOKIMITSU, I.; WILDER, D.; JONES, F.; BLUMBERG, J. B.; CARTWRIGHT, Y. Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults. The Journal of nutrition, 2008, 139.2: 264-270. PMID:19074207, CHEN, I-Ju; et al. Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial. Clinical Nutrition, 2016, 35.3: 592-599. PMID:26093535.
  
  
• Griffonia (Griffonia Simplicifolia)
  Derived from the seeds of an African plant, Griffonia Extract is used to create 5-HTP. This substance produces a calm, relaxed state of mind that is thought to improve sleep. Research suggests that sleep deprivation alters hunger-regulating hormones, causing an increase in appetite and a desire for calorie-dense foods. Species: Griffonia Simplicifolia, Family: Fabaceae, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH3281B0, References: Weight Loss: RONDANELLI, M.; OPIZZI, A.; FALIVAI, M.; BUCCI, M.; PERNA, S. Relationship between the absorption of 5-hydroxytryptophan from an integrated diet, by means of Griffonia simplicifolia extract, and the effect on satiety in overweight females after oral spray administration. Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity, 2012, 17.1: e22-e28. PMID:22142813.
  
  
• Hops (Humulus Lupulus)
  When you hear “hops,” the first thing that comes to mind is probably beer. But the dried parts of this plant are used for more than just your favorite brews! In fact, Hops Extract is regularly used to treat insomnia and other sleep disorders. The best part is that restful sleep supports your weight loss, offering multiple benefits in one! Species: Humulus Lupulus,
  Family: Cannabaceae,
  European Medicines Agency: EMA: Lupuli Flos,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH32A8C0,
  References:
  Weight Loss: MORIMOTO-KOBAYASHI, Yumie; OHARA, K.; ASHIGAI, H.; KANAYA, T.; KOIZUMI, K.; MANABE, F.; KANEKO, Y.; TANIGUCHI, Y.; KATAYAMA, M.; KOWATARI, Y.; KONDO, S. Matured hop extract reduces body fat in healthy overweight humans: a randomized, double-blind, placebo-controlled parallel group study. Nutrition journal, 2015, 15.1: 25. PMID:26960416.
  
  
• Chromium (Cr)
  If you’re into strength training, you may know chromium picolinate as a supplement useful in building muscle, burning fat, and metabolizing carbohydrates. Beyond these benefits, chromium moves blood sugar, also known as glucose, from your bloodstream into your cells. Here, glucose can be used to transform the macronutrients you eat – fats, carbohydrates, and proteins – into energy. Allows you to reduce the problem of snacking. Thanks to the stabilization of blood sugar, it suppresses the appetite. Supports the metabolism of macronutrients.
  Chromium: Chromium, PubChem CID: 23976, Chemical Abstracts Service: CAS: 7440-47-3, ChemIDplus: 7440-47-3, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS29A810, References: Weight Loss: ONAKPOYA, I.; POSADZKI, P.; ERNST, E. Chromium supplementation in overweight and obesity: a systematic review and meta‐analysis of randomized clinical trials. Obesity reviews, 2013, 14.6: 496-507. PMID:23495911, PITTLER, M. H.; STEVINSON, C.; ERNST, E. Chromium picolinate for reducing body weight: meta-analysis of randomized trials. International journal of obesity, 2003, 27.4: 522. PMID:12664086.
  
  • Chromium (chromium picolinate) (C₁₈H₁₂CrN₃O₆)
    
    Chromium (chromium picolinate): Chromium Picolinate, Picolinic Acid Chromium(III) Salt, Chromium(III) Picolinate,
    PubChem CID: 151932,
    Chemical Abstracts Service: CAS: 14639-25-9,
    ChemIDplus: 14639-25-9,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS29A810-1,
    References:
    Weight Loss: PITTLER, M. H.; STEVINSON, C.; ERNST, E. Chromium picolinate for reducing body weight: meta-analysis of randomized trials. International journal of obesity, 2003, 27.4: 522. PMID:12664086, DOCHERTY, John P.; SACK, D. A.; ROFFMAN, M.; FINCH, M.; KOMOROWSKI, J. R. A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving. Journal of Psychiatric Practice®, 2005, 11.5: 302-314. PMID:16184071.
    
• Molybdenum (Mo)
  Your body’s cells can’t produce energy on their own. But with molybdenum, they can use broken-down macronutrients to create energy. This kind of energy doesn’t just fuel your day and workouts. It also helps you digest your food, regulates your heartbeat, promotes healthy muscle functioning, and creates new, healthy cells.
  Molybdenum: Molybdenum, PubChem CID: 23932, Chemical Abstracts Service: CAS: 7439-98-7, ChemIDplus: 7439-98-7, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS32F6E0.
  
  • Molybdenum (Sodium Molybdate) (Na₂MoO₄ or MoNa₂O₄)
    
    Molybdenum (Sodium Molybdate): Sodium Molybdate, Sodium Molybdate(VI), Disodium Molybdate, Natriummolybdat, Molybdate Disodium, Sodium Dimolybdate, Disodium Tetraoxomolybdate,
    PubChem CID: 61424,
    Chemical Abstracts Service: CAS: 7631-95-0,
    ChemIDplus: 7631-95-0,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 948QAQ08I1,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS32F6E0-1.
    
• Vitamin B
  Vitamin B: Vitamin B, B Vitamins, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISCACA10.
  
  • Vitamin B7 (biotin) (C₁₀H₁₆N₂O₃S)
    Biotin is often associated with hair and nail health, but it also aids in weight loss. As an important component of enzymes that work to break down fats, carbohydrates, and other substances in your body, Biotin helps prevent fat storage due to excess calorie intake.
    Vitamin B7 (biotin): Biotin, D-Biotin, Coenzyme R, Vitamin B7, Vitamin H,
    PubChem CID: 171548,
    Chemical Abstracts Service: CAS: 58-85-5,
    ChemIDplus: 58-85-5,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA05,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 6SO6U10H04,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS269AD0.
    
  • Vitamin B1 (thiamine/aneurine) (C₁₂H₁₇N₄OS⁺)
    Eight B vitamins help your body convert food, especially carbohydrates, into glucose that it can use as energy. Vitamin B1 is no different – it also helps your body metabolize fats and protein, ensuring you get all the nutrients you need from your food.
    Vitamin B1 (thiamine/aneurine): Thiamine, Vitamin B1, Aneurin, Antiberiberi Factor, Thiadoxine, Betaxin, Thiamin,
    PubChem CID: 1130,
    Chemical Abstracts Service: CAS: 70-16-6,
    ChemIDplus: 70-16-6,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11DA01,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: X66NSO3N35,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2A6B60,
    References:
    Weight Loss: KERNS, Jennifer C.; ARUNDEL, Cherinne; CHAWLA, Lakhmir S. Thiamin deficiency in people with obesity. Advances in nutrition, 2015, 6.2: 147-153. PMID:25770253.
    
  • Vitamin B6 (Pyridoxine) (C₈H₁₁NO₃)
    Though all B vitamins are essential, Vitamin B6 is one of the most important. It plays a role in over 100 enzyme reactions in the body, primarily in the metabolism of important amino acids and proteins. Participates in the synthesis of hemoglobin and activates the SIRT gene also known as the gene of slenderness. Vitamin B6 ensures proper energy metabolism. It regulates the functioning of the endocrine system and maintains internal balance.
    Vitamin B6 (Pyridoxine): Pyridoxine, Gravidox, Pyridoxol, Vitamin B6,
    PubChem CID: 1054,
    Chemical Abstracts Service: CAS: 65-23-6,
    ChemIDplus: 65-23-6,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA02,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: KV2JZ1BI6Z,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS264CB0,
    References:
    Weight Loss: NOVIN, Zahra Shakibay; GHAVAMZADEH, Saeed; MEHDIZADEH, Alireza The Weight Loss Effects of Branched Chain Amino Acids and Vitamin B6: A Randomized Controlled Trial on Obese and Overweight Women. International Journal for Vitamin and Nutrition Research, 2019, 2019: . PMID:30841823.
    
  • Vitamin B5 (Pantothenic Acid) (C₉H₁₇NO₅)
    More commonly known as vitamin B5, pantothenic acid helps your body metabolize food into energy while assisting your liver in metabolizing toxins that can stall your weight loss efforts.
    Vitamin B5 (Pantothenic Acid): D-Pantothenic Acid, Vitamin B5, Pantothenic Acid, Pantothenate,
    PubChem CID: 6613,
    Chemical Abstracts Service: CAS: 79-83-4,
    ChemIDplus: 79-83-4,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA31,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 19F5HK2737,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS26C1E0,
    References:
    Weight Loss: LEUNG, L. H. Pantothenic acid as a weight-reducing agent: fasting without hunger, weakness and ketosis. Medical hypotheses, 1995, 44.5: 403-405. PMID:8583972.
    
• Vitamin C (Ascorbic Acid) (C₆H₈O₆)
  Like all 8 B vitamins, vitamin C aids in protein metabolism. This means it not only provides your body with necessary proteins, but does so while blocking the synthesis of proteins known to cause infection and inflammation. That means if you go to the gym often, vitamin C can make it easier for you to recover after training.
  Vitamin C (Ascorbic Acid): Ascorbic Acid, L-Ascorbic Acid, L(+)-Ascorbic Acid, Vitamin C,
  PubChem CID: 54670067,
  Chemical Abstracts Service: CAS: 50-81-7,
  ChemIDplus: 50-81-7,
  WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11GA01,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: PQ6CK8PD0R,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2D5190,
  References:
  Weight Loss: GARCIA-DIAZ, Diego Fernando; et al. Vitamin C in the Treatment and/or Prevention of Obesity. Journal of nutritional science and vitaminology, 2014, 60.6: 367-379. PMID:25866299, JOHNSTON, Carol S. Strategies for healthy weight loss: from vitamin C to the glycemic response. Journal of the American College of Nutrition, 2005, 24.3: 158-165. PMID:15930480.
  
• Choline Bitartrate (C₉H₁₉NO₇)
  Choline addresses your weight loss and health from multiple perspectives by not only controlling fat storage and regulating your cholesterol, but regulating the health of your kidneys, liver, and gallbladder too. The best part is that it fights fatigue, giving you the energy to get through your workout (and day) without falling short on your weight loss efforts.
  Choline Bitartrate: Choline Bitartrate, Choline Tartrate, Choline-Bitartrate, Cholini Bitartras, Cholinibitatratis,
  PubChem CID: 6900,
  Chemical Abstracts Service: CAS: 87-67-2,
  ChemIDplus: 87-67-2,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS32CFD0-1.
  

Recommended intake of this supplement: 3 capsule, daily (adults).