What are the properties of Konjac Glucomannan in supplements?

Konjac Glucomannan - References & External links

Konjac Glucomannan (Amorphophallus Konjac)

The references to scientific articles about Konjac Glucomannan are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• The general properties of Konjac Glucomannan:
  • BEHERA, Sudhanshu S.; RAY, Ramesh C. Konjac glucomannan, a promising polysaccharide of Amorphophallus konjac K. Koch in health care. International journal of biological macromolecules, 2016, 92: 942-956. PMID:27481345
  • TESTER, Richard F.; AL-GHAZZEWI, Farage H. Beneficial health characteristics of native and hydrolysed konjac (Amorphophallus konjac) glucomannan. Journal of the Science of Food and Agriculture, 2016, 96.10: 3283-3291. PMID:26676961
  • ZHANG, Cui; et al. Konjac glucomannan, a promising polysaccharide for OCDDS. Carbohydrate polymers, 2014, 104: 175-181. PMID:24607175
  • JIANG, Min; et al. Depolymerized konjac glucomannan: preparation and application in health care. Journal of Zhejiang University-SCIENCE B, 2018, 19.7: 505-514. PMID:29971989
  • CHUA, Melinda; et al. Traditional uses and potential health benefits of Amorphophallus konjac K. Koch ex N.E.Br. Journal of ethnopharmacology, 2010, 128.2: 268-278. PMID:20079822
  • DEVARAJ, Ramya Devi; REDDY, Chagam Koteswara; XU, Baojun. Health-promoting effects of konjac glucomannan and its practical applications: A critical review. International journal of biological macromolecules, 2018. PMID:30586587
  • KRAEMER, William J.; et al. Effect of adding exercise to a diet containing glucomannan. Metabolism, 2007, 56.8: 1149-1158. PMID:17618964
  • CHEN, Hsiao-Ling; et al. Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted bowel movement and improved colonic ecology in constipated adults: a placebo-controlled, diet-controlled trial. Journal of the American College of Nutrition, 2008, 27.1: 102-108. PMID:18460488
    CONCLUSION: The modest dose of KGM supplement promoted bowel movement by 30% and improved colonic ecology in constipated adults.
• The properties of Konjac Glucomannan for Weight Loss:
  Glucomannan is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). As a dietary fiber, Glucomannan absorbs water and maintains a feeling of satiation, effectively reducing cravings. It means you’ll be less likely to eat later in the evening, keeping the cravings that can compromise your diet at bay.
  • KAATS, Gilbert R.; BAGCHI, Debasis; PREUSS, Harry G. Konjac glucomannan dietary supplementation causes significant fat loss in compliant overweight adults. Journal of the American College of Nutrition, 2015, 2015: 1-7. PMID:26492494
    CONCLUSIONS: This study supports the efficacy glucomannan supplementation to reduce body weight, body fat, and circulating cholesterol levels without the concomitant loss of lean mass and bone density often associated with weight loss. However, these positive outcomes were not observable until corrections for compliance were applied.
  • MAIA-LANDIM, Andrea; et al. Long-term effects of Garcinia cambogia/Glucomannan on weight loss in people with obesity, PLIN4, FTO and Trp64Arg polymorphisms. BMC complementary and alternative medicine, 2018, 18.1: 26. PMID:29361938
    CONCLUSIONS: Administration of GC and GNN reduce weight and improve lipid and glucose blood profiles in people with overweight or obesity, although the presence of polymorphisms PLIN4, FTO and ADRB3 might hinder in some degree these effects. ISRCTN78807585, 19 September 2017, retrospective study.
  • VITA, P. M.; et al. Chronic use of glucomannan in the dietary treatment of severe obesity. Minerva medica, 1992, 83.3: 135-139. PMID:1313163
  • WALSH, David E.; YAGHOUBIAN, Vazgen; BEHFOROOZ, Ali. Effect of glucomannan on obese patients: a clinical study. International journal of obesity, 1984, 8.4: 289-93. PMID:6096282
  • PITTLER, Max H.; ERNST, Edzard. Dietary supplements for body-weight reduction: a systematic review. The American journal of clinical nutrition, 2004, 79.4: 529-536. PMID:15051593
    CONCLUSIONS: The evidence for most dietary supplements as aids in reducing body weight is not convincing. None of the reviewed dietary supplements can be recommended for over-the-counter use.
  • VASQUES, Carlos A. R.; ROSSETTO, Simone; HALMENSCHLAGER, Graziele; LINDEN, Rafael; HECKLER, Eliane; POBLADOR FERNANDEZ, Maria S.; LANCHO ALONSO, José L. Evaluation of the pharmacotherapeutic efficacy of Garcinia cambogia plus Amorphophallus konjac for the treatment of obesity. Phytotherapy Research, 2008, 22.9: 1135-1140. PMID:18729243
• The properties of Konjac Glucomannan in supporting diabets treatment:
  • CHEN, Hsiao-Ling; et al. Konjac supplement alleviated hypercholesterolemia and hyperglycemia in type 2 diabetic subjects--a randomized double-blind trial. Journal of the American College of Nutrition, 2003, 22.1: 36-42. PMID:12569112
    CONCLUSIONS: The KGM supplement improved blood lipid levels by enhancing fecal excretion of neutral sterol and bile acid and alleviated the elevated glucose levels in diabetic subjects. KGM could be an adjunct for the treatment of hyperlipidemic diabetic subjects.
  • YOSHIDA, M.; et al. Effect of plant sterols and glucomannan on lipids in individuals with and without type II diabetes. European journal of clinical nutrition, 2006, 60.4: 529. PMID:16391591
    CONCLUSIONS: The results suggest that glucomannan and a combination of glucomannan and plant sterols substantially improves plasma LDL cholesterol concentrations. SPONSORSHIP: Forbes Medi-Tech Inc., Vancouver, British Columbia, Canada.
• The properties of Konjac Glucomannan reducing Cholesterol:
  • HO, Hoang Vi Thanh; et al. A systematic review and meta-analysis of randomized controlled trials of the effect of konjac glucomannan, a viscous soluble fiber, on LDL cholesterol and the new lipid targets non-HDL cholesterol and apolipoprotein B. The American journal of clinical nutrition, 2017, 105.5: 1239-1247. PMID:28356275
    Conclusions: Our findings support the intake of ∼3 g KJM/d for reductions in LDL cholesterol and non-HDL cholesterol of 10% and 7%, respectively. The information may be of interest to health agencies in crafting future dietary recommendations related to reduction in CVD risk. This study was registered at clinicaltrials.gov as NCT02068248.
  • GALLAHER, Daniel D.; et al. A glucomannan and chitosan fiber supplement decreases plasma cholesterol and increases cholesterol excretion in overweight normocholesterolemic humans. Journal of the American College of Nutrition, 2002, 21.5: 428-433. PMID:12356785
    CONCLUSIONS: Serum cholesterol reduction by a chitosan/glucomannan supplement is likely mediated by increased fecal steroid excretion and is not linked to fat excretion.
• The properties of Konjac Glucomannan preventing Acne:
  • AL-GHAZZEWI, Farage H.; TESTER, R. F. Effect of konjac glucomannan hydrolysates and probiotics on the growth of the skin bacterium Propionibacterium acnes in vitro. International journal of cosmetic science, 2010, 32.2: 139-142. PMID:19818083