Brain Actives

Brain Actives – Ingredientes

• Performance & Energy Booster
  
• Theacrine – TeaCrine® (125 Mg)
  • TeaCrine® (C₉H₁₂N₄O₃)
    Un ingrediente que libera tu máximo potencial Extremadamente eficaz al combinarse con la cafeína. No causa irritación ni el choque típico de la cafeína. Independientemente de si esperas un apoyo en el esfuerzo mental o durante el entrenamiento en el gimnasio, la TeaCrina® te ayuda con la misma eficacia.
    TeaCrine®: Theacrine, Tetramethyluric Acid, Temurin, Temorine, 1,3,7,9-Tetramethyluric Acid, Tetramethyl Uric Acid, PubChem CID: 75324, Chemical Abstracts Service: CAS: 2309-49-1, ChemIDplus: 2309-49-1, FDA Substance Registration System – Unique Ingredient Identifier: UNII: EJ939L81MY, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISAA22B0, References: Brain / Mental Clarity: ZIEGENFUSS, Tim N.; et al. A Two-Part Approach to Examine the Effects of Theacrine (TeaCrine®) Supplementation on Oxygen Consumption, Hemodynamic Responses, and Subjective Measures of Cognitive and Psychometric Parameters. Journal of dietary supplements, 2017, 14.1: 9-24. PMID:27164220, TAYLOR, Lem; et al. Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use. Journal of the International Society of Sports Nutrition, 2016, 13.1: 2. PMID:26766930.
    
• Natural Caffeine Anhydrous (150 Mg)
  • Cafeína (C₈H₁₀N₄O₂)
    Cafeína: mejora el tiempo de respuesta, reduce la fatiga, aumenta la resistencia física, ayuda a incrementar el estado de alerta.
    Cafeína: Caffeine, 1,3,7-Trimethylxanthine, Thein,
    PubChem CID: 2519,
    Chemical Abstracts Service: CAS: 58-08-2,
    ChemIDplus: 58-08-2,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: N06BC01,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2C8E40,
    References:
    Brain / Mental Clarity: BELLO, Marissa L.; et al. The effects of TeaCrine® and caffeine on endurance and cognitive performance during a simulated match in high-level soccer players. Journal of the International Society of Sports Nutrition, 2019, 16.1: 20. PMID:30999897, DIETZ, Christina; DEKKER, Matthijs Effect of Green Tea Phytochemicals on Mood and Cognition. Current pharmaceutical design, 2017, 23.19: 2876-2905. PMID:28056735.
    
• Cognitive & Nootropic Complex
  
• Ashwagandha Root Extract [5% Withanolides] – KSM-66® (300 Mg)
  • Ashwagandha (Withania Somnifera)
    Ashwagandha: mejora la memoria, aumenta la capacidad de aprendizaje, apoya la capacidad cognitiva, ayuda a reducir el estrés. Species: Withania Somnifera,
    Family: Solanaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH9BA3C0,
    References:
    Brain / Mental Clarity: ANDRADE, Chittaranjan; et al. A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera. Indian journal of psychiatry, 2000, 42.3: 295. PMID:21407960, YENISETTI, Sarat; et al. Neuropharmacological Properties of Withania somnifera – Indian Ginseng: An Overview on Experimental Evidence with Emphasis on Clinical Trials and Patents. Recent patents on CNS drug discovery, 2015, 10.2: 204-215. PMID:27316579,
    Stress / Relaxation: CHANDRASEKHAR, K.; KAPOOR, Jyoti; ANISHETTY, Sridhar A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian journal of psychological medicine, 2012, 34.3: 255. PMID:23439798, SALVE, Jaysing; et al. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus, 2019, 11.12: e6466. PMID:32021735.
    
    
  • KSM-66®
    KSM-66®: KSM-66®, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISAA49C0, References: Sports Nutrition: CHOUDHARY, Bakhtiar; SHETTY, A.; LANGADE, Deepak G. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. Ayu, 2015, 36.1: 63. PMID:26730141.
    
• Bacopa Monnieri Herb Extract [50% Bacosides] – Bacopin® (150 Mg)
  • Bacopa Monnieri (Bacopa Monnieri)
    Ayuda a retener los conocimientos, fortalece la capacidad de concentración, mejora la función cerebral, mejora las funciones cognitivas. La planta india bacopa monnieri contiene componentes llamados bacosides a los que se atribuyen propiedades para reparar neuronas dañadas y promover el crecimiento de nuevos nervios. Ello significa una mejora en la comunicación neuronal con el cerebro, ayudando a la la función cognitiva y el rendimiento mental. Species: Bacopa Monnieri,
    Family: Plantaginaceae,
    Domain: Plantae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH358EF0,
    References:
    Brain / Mental Clarity: MCPHEE, G. M.; DOWNEY, L. A.; NOBLE, A.; STOUGH, C. Cognitive training and Bacopa monnieri: Evidence for a combined intervention to alleviate age associated cognitive decline. Medical hypotheses, 2016, 95: 71-76. PMID:27692172, MORGAN, A.; STEVENS, J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. The journal of alternative and complementary medicine, 2010, 16.7: 753-759. PMID:20590480.
    
    
  • Bacopin®
    Bacopin®: Bacopin®, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISAA70D0.
    
• Gotu Kola Leaf Extract [8% Triterpenes] – Centellin® (50 Mg)
  • Gotu Kola (Centella Asiatica)
    Gotu Kola: nootrópico conocido, revitaliza el cerebro y el sistema nervioso, aumenta la capacidad de atención, mejora la memoria a largo plazo. Species: Centella Asiatica,
    Family: Apiaceae Mackinlayaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH4FA6A0,
    References:
    Brain / Mental Clarity: PUTTARAK, Panupong; et al. Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis. Scientific reports, 2017, 7.1: 10646. PMID:28878245, SHINOMOL, G. K.; et al. Exploring the Role of “Brahmi” (Bacopa monnieri and Centella asiatica) in Brain Function and Therapy. Recent patents on endocrine, metabolic & immune drug discovery, 2011, 5.1: 33-49. PMID:22074576,
    Cardiovascular Support: RAZALI, Nur Nadia Mohd; NG, Chin Theng; FONG, Lai Yen Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review. Planta medica, 2019, 85.16: 1203-1215. PMID:31539918.
    
    
  • Centellin®
    Centellin®: Centellin®, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2D2A80.
    
  • Triterpenes (C₃₀H₄₈)
    Triterpenes: Triterpenes, Triterpene, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS391160.
    
    • Madecassol (C₄₈H₇₈O₁₉)
      Madecassol: Madecassol, Asiaticoside, Centelase, Blastostimulina,
      PubChem CID: 11954171,
      Chemical Abstracts Service: CAS: 16830-15-2,
      ChemIDplus: 16830-15-2,
      FDA Substance Registration System – Unique Ingredient Identifier: UNII: PKO39VY215,
      The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISEDBB60.
      
    • Brahmoside
      Brahmoside: Brahmoside, Brahminoside, PubChem CID: 395762, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED9450.
      
    • Asiatic Acid (C₃₀H₄₈O₅)
      Asiatic Acid: Asiatic Acid, Asiantic Acid, Dammarolic Acid,
      PubChem CID: 119034,
      Chemical Abstracts Service: CAS: 464-92-6,
      ChemIDplus: 464-92-6,
      FDA Substance Registration System – Unique Ingredient Identifier: UNII: 9PA5A687X5,
      The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED6D40.
      
    • Madecassic Acid (C₃₀H₄₈O₆)
      Madecassic Acid: Madecassic Acid, Brahmic Acid, 6Beta-Hydroxyasiatic Acid,
      PubChem CID: 73412,
      Chemical Abstracts Service: CAS: 18449-41-7,
      ChemIDplus: 18449-41-7,
      FDA Substance Registration System – Unique Ingredient Identifier: UNII: M7O1N24J82,
      The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED4630.
      
• Black Pepper Fruit Extract [95% Piperine] – BioPerine® (5 Mg)
  • Black Pepper (Piper Nigrum)Species: Piper Nigrum,
    Family: Piperaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2CB550,
    References:
    Brain / Mental Clarity: JOSHI, Hanumanthachar; PARLE, Milind Effects of piperine on memory and behavior mediated via monoamine neurotransmiters. Journal of Traditional Medicines, 2005, 22.2+ 3: 39-43., NEWERLI-GUZ, Joanna; ŚMIECHOWSKA, Maria Assessment of the contents of piperine in black pepper berries Piper nigrum L. Bromatologia i Chemia Toksykologiczna, 2009, XLII: 827–830..
    
    
  • BioPerine®
    BioPerine® es una innovadora forma de piperina libre de los productos químicos utilizados en el cultivo de plantas, como fertilizantes, concentrados, acondicionadores, pesticidas u otros productos fitosanitarios. Su seguridad de uso ha sido confirmada por diversos estudios realizados por la Autoridad Europea de Seguridad Alimentaria (EFSA). Gracias a su mejor absorción y uso de esta forma, en comparación con la forma convencional, se puede observar un aumento significativo en la biodisponibilidad del resto de componentes valiosos de este suplemento. Esto lleva a multiplicar hasta en 30 veces los efectos de su acción. Además, BioPerine® contiene más piperina que el extracto de pimienta negra, lo que mejora aún más la eficacia del producto.
    BioPerine®: BioPerine®,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS28E4C0.
    
  • Piperine (C₁₇H₁₉NO₃)
    Piperine: Piperine, Bioperine, Piperin, 1-Piperoylpiperidine, Piperoylpiperidine, 1-Piperylpiperidine,
    PubChem CID: 638024,
    Chemical Abstracts Service: CAS: 94-62-2,
    ChemIDplus: 94-62-2,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS395F80,
    References:
    Brain / Mental Clarity: JOSHI, Hanumanthachar; PARLE, Milind Effects of piperine on memory and behavior mediated via monoamine neurotransmiters. Journal of Traditional Medicines, 2005, 22.2+ 3: 39-43..
    
• Neuro Vita-Min Blend
  
• Vitamin B6 (14 Mg)
  • La Vitamina B6 (piridoxina) (C₈H₁₁NO₃)
    Necesaria para la biosíntesis de varios neurotransmisores incluyendo la dopamina, serotonina y GABA. CILTEP presenta la forma metabólicamente activa de la vitamina B6 (Fosfato de Piridoxal-5) para asegurar una óptima función cognitiva.
    La Vitamina B6 (piridoxina): Pyridoxine, Gravidox, Pyridoxol, Vitamin B6,
    PubChem CID: 1054,
    Chemical Abstracts Service: CAS: 65-23-6,
    ChemIDplus: 65-23-6,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA02,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: KV2JZ1BI6Z,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS264CB0,
    References:
    Cardiovascular Support: FRISO, Simonetta; et al. Vitamin B6 and Cardiovascular Disease. In: Water Soluble Vitamins. Springer, Dordrecht, 2012, 56: 265-290. PMID:22116704, JEON, Jimin; PARK, Kyong Dietary Vitamin B 6 Intake Associated With a Decreased Risk of Cardiovascular Disease: A Prospective Cohort Study. Nutrients, 2019, 11.7: 1484. PMID:31261898,
    Brain / Mental Clarity: BOURRE, Jean-Marie Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. Journal of Nutrition Health and Aging, 2006, 10.5: 377. PMID:17066209, RAMOS, Rúben J.; et al. Vitamin B6 Is Essential for Serine De Novo Biosynthesis. Journal of inherited metabolic disease, 2017, 40.6: 883-891. PMID:28801717,
    Stress / Relaxation: POUTEAU, Etienne; et al. Superiority of Magnesium and Vitamin B6 Over Magnesium Alone on Severe Stress in Healthy Adults With Low Magnesemia: A Randomized, Single-Blind Clinical Trial. PloS one, 2018, 13.12: e0208454. PMID:30562392, KELLY, Gregory S. Nutritional and Botanical Interventions to Assist With the Adaptation to Stress. Alternative medicine review: a journal of clinical therapeutic, 1999, 4.4: 249-265. PMID:10468649,
    Sports Nutrition: MANORE, Melinda M. Vitamin B6 and Exercise. International Journal of Sport Nutrition and Exercise Metabolism, 1994, 4.2: 89-103. PMID:8054964.
    
• Vitamin B12 (25 μg)
  • Vitamina B12 (cobalamina, cianocobalamina) (C₆₃H₈₈CoN₁₄O₁₄P)
    Vitamina B12 (cobalamina, cianocobalamina): Cyanocobalamin, Vitamin B12, Cobalamin, Crystamine, Anacobin,
    PubChem CID: 5311498,
    Chemical Abstracts Service: CAS: 68-19-9,
    ChemIDplus: 68-19-9,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: B03BA01,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: P6YC3EG204,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS30D400,
    References:
    Brain / Mental Clarity: SMITH, A. David; WARREN, Martin J.; REFSUM, Helga Vitamin B12. In: Advances in food and nutrition research. Academic Press, 2018, 2018: 215-279. PMID:29477223, TANGNEY, C. C.; AGGARWAL, N. T.; LI, H.; WILSON, R. S.; DECARLI, C.; EVANS, D. A.; MORRIS, M. C. Vitamin B12, cognition, and brain MRI measures: a cross-sectional examination. Neurology, 2011, 77.13: 1276-1282. PMID:21947532,
    Stress / Relaxation: KELLY, Gregory S. Nutritional and Botanical Interventions to Assist With the Adaptation to Stress. Alternative medicine review: a journal of clinical therapeutic, 1999, 4.4: 249-265. PMID:10468649.
    
• Pantothenic Acid (15 Mg)
  • La Vitamina B5 (ácido pantoténico) (C₉H₁₇NO₅)
    La Vitamina B5 (ácido pantoténico): D-Pantothenic Acid, Vitamin B5, Pantothenic Acid, Pantothenate,
    PubChem CID: 6613,
    Chemical Abstracts Service: CAS: 79-83-4,
    ChemIDplus: 79-83-4,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA31,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 19F5HK2737,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS26C1E0,
    References:
    Brain / Mental Clarity: KENNEDY, David O. B Vitamins and the Brain: Mechanisms, Dose and Efficacy–A Review. Nutrients, 2016, 8.2: 68. PMID:26828517,
    Stress / Relaxation: KELLY, Gregory S. Nutritional and Botanical Interventions to Assist With the Adaptation to Stress. Alternative medicine review: a journal of clinical therapeutic, 1999, 4.4: 249-265. PMID:10468649.
    
• Magnesium – Aquamin™ Mg (75 Mg)
  • Magnesio (Mg)
    Magnesio: Magnesium, PubChem CID: 5462224, Chemical Abstracts Service: CAS: 7439-95-4, ChemIDplus: 7439-95-4, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS371590, References: Brain / Mental Clarity: BOURRE, Jean-Marie Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. Journal of Nutrition Health and Aging, 2006, 10.5: 377. PMID:17066209, HUSKISSON, E.; MAGGINI, S.; RUF, M. The influence of micronutrients on cognitive function and performance. Journal of international medical research, 2007, 35.1: 1-19. PMID:17408051, Stress / Relaxation: POUTEAU, Etienne; et al. Superiority of Magnesium and Vitamin B6 Over Magnesium Alone on Severe Stress in Healthy Adults With Low Magnesemia: A Randomized, Single-Blind Clinical Trial. PloS one, 2018, 13.12: e0208454. PMID:30562392, Sports Nutrition: CINAR, Vedat; et al. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion. Biological trace element research, 2011, 140.1: 18-23. PMID:20352370.