Herbs - References & External links
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Senna (Senna Alexandrina) is a world's natural laxative medicinal plant. Laxative properties are due to sennosides (anthraquinone glycosides) natural products.- VILANOVA-SANCHEZ, Alejandra; et al. Are Senna based laxatives safe when used as long term treatment for constipation in children? Journal of pediatric surgery, 2018, 53.4: 722-727. PMID:29429768
CONCLUSION: There is a paucity of information in the literature regarding side effects of sennosides as a long-term therapy, and to our knowledge, this is the first review of Senna side effects in children. Senna induced dermatitis is rare, but may occur when patients need a higher dose. All of the cases described had a long period of exposure of the skin to stool. Besides the perineal rash with blisters, we could find no other described major side effect with Senna administration in the pediatric population or evidence of the frequently mentioned concern of the development of tolerance to Senna. Pediatric caregivers should advise families of the rare side effect of skin blistering and educate them to change the diaper frequently in children who are not toilet- trained to reduce stool to skin exposure. We can conclude from this review that Senna is a safe treatment option for constipation in children. LEVEL OF EVIDENCE: IV.
- VILANOVA-SANCHEZ, Alejandra; et al. Are Senna based laxatives safe when used as long term treatment for constipation in children? Journal of pediatric surgery, 2018, 53.4: 722-727. PMID:29429768