What are the properties of Silibinin in supplements?

The properties of Silibinin

Silibinin (INN), also known as silybin, is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin, and others. Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. The mixture exhibits a number of pharmacological effects, particularly in the liver, and there is some clinical evidence for the use of silibinin as a supportive element in alcoholic and child grade ‘A’ liver cirrhosis.


Silibinin - Description from ChEBI

 

Silibinin - Description from DrugBank

 


The supplements containing Silibinin

Milk Thistle Seed, 120 Vegan Liquid Phyto-Caps (Gaia Herbs)Milk Thistle Seed, 120 Vegan Liquid Phyto-Caps (Gaia Herbs)

English version

Cleansing Healthy Liver Support Herbs Liquid Supplements TBSS ID:
Milk Thistle Seed, 120 Vegan Liquid Phyto-Caps (Gaia Herbs) contains amoung others Silibinin.

Milk Thistle Seed, 120 Vegan Liquid Phyto-Caps (Gaia Herbs) is available in many countries around the world.

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Milk Thistle Seed, 120 Vegan Liquid Phyto-Caps (Gaia Herbs)
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Silymarin, Milk Thistle Extract with Artichoke & Dandelion, Double Strength, 300 mg, 200 Veg Capsules (Now Foods)Silymarin, Milk Thistle Extract with Artichoke & Dandelion, Double Strength, 300 mg, 200 Veg Capsules (Now Foods)

English version

Healthy Liver Support Herbs TBSS ID:
Silymarin, Milk Thistle Extract with Artichoke & Dandelion, Double Strength, 300 mg, 200 Veg Capsules (Now Foods) contains amoung others Silibinin.

Silymarin, Milk Thistle Extract with Artichoke & Dandelion, Double Strength, 300 mg, 200 Veg Capsules (Now Foods) is available in many countries around the world.

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Silymarin (Silybum marianum), also known as Milk Thistle, has been used by traditional herbalists for centuries. Scientific studies have indicated that constituents in Silymarin may help to support healthy liver function. This vegetarian formula also includes Artichoke & Dandelion for additional...
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Silymarin, Milk Thistle Extract, 150 mg, 120 Veg Capsules (Now Foods)Silymarin, Milk Thistle Extract, 150 mg, 120 Veg Capsules (Now Foods)

English version

Healthy Liver Support Herbs TBSS ID:
Silymarin, Milk Thistle Extract, 150 mg, 120 Veg Capsules (Now Foods) contains amoung others Silibinin.

Silymarin, Milk Thistle Extract, 150 mg, 120 Veg Capsules (Now Foods) is available in many countries around the world.

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Silymarin (Silybum marianum), also known as Milk Thistle, has been used by traditional herbalists for centuries. Scientific studies have indicated that constituents in Silymarin may help to support healthy liver function. This vegetarian formula also includes Turmeric for additional support.
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Liver Refresh, 180 Veg Capsules (Now Foods)Liver Refresh, 180 Veg Capsules (Now Foods)

English version

Healthy Liver Support Herbs TBSS ID:
Liver Refresh, 180 Veg Capsules (Now Foods) contains amoung others Silibinin.

Liver Refresh, 180 Veg Capsules (Now Foods) is available in many countries around the world.

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Help support liver health and your body's vital detoxification processes with NOW Liver Refresh, a combination of nutrients and herbs designed to support the liver's role in these processes. Liver Refresh combines milk thistle extract with a unique herb-enzyme blend to create a balanced botanical...
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Silymarin, Milk Thistle Extract with Artichoke & Dandelion, Double Strength, 300 mg, 100 Veg Capsules (Now Foods)Silymarin, Milk Thistle Extract with Artichoke & Dandelion, Double Strength, 300 mg, 100 Veg Capsules (Now Foods)

English version

Healthy Liver Support Herbs TBSS ID:
Silymarin, Milk Thistle Extract with Artichoke & Dandelion, Double Strength, 300 mg, 100 Veg Capsules (Now Foods) contains amoung others Silibinin.

Silymarin, Milk Thistle Extract with Artichoke & Dandelion, Double Strength, 300 mg, 100 Veg Capsules (Now Foods) is available in many countries around the world.

If you are not in The United Kingdom (GB)
>> Select Your Country <<

 

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Silymarin Flavonoids (Silybum Marianum), also known as Milk Thistle, has been used by traditional herbalists for centuries. Scientific studies have indicated that constituents in Silymarin may help to support healthy liver function. This vegetarian formula also includes Artichoke & Dandelion for...
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Liver Refresh, 90 Veg Capsules (Now Foods)Liver Refresh, 90 Veg Capsules (Now Foods)

English version

Healthy Liver Support Herbs TBSS ID:
Liver Refresh, 90 Veg Capsules (Now Foods) contains amoung others Silibinin.

Liver Refresh, 90 Veg Capsules (Now Foods) is available in many countries around the world.

If you are not in The United Kingdom (GB)
>> Select Your Country <<

 

Learn More (GB)
Helps support liver health and your body's vital detoxification processes with NOW Liver Refresh, a combination of nutrients and herbs designed to support the liver's role in these processes. Liver Refresh combines milk thistle extract with a unique herb-enzyme blend to create a balanced botanical...
Learn More (GB)
Silymarin, Extra Strength, 120 Softgels (Now Foods)Silymarin, Extra Strength, 120 Softgels (Now Foods)

English version

Healthy Liver Support Herbs TBSS ID:
Silymarin, Extra Strength, 120 Softgels (Now Foods) contains amoung others Silibinin.

Silymarin, Extra Strength, 120 Softgels (Now Foods) is available in many countries around the world.

If you are not in The United Kingdom (GB)
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Milk Thistle (Silybum Marianum) has been used by traditional herbalists for centuries. Clinical and non-clinical studies have indicated that Milk Thistle extract may help maintain healthy liver function through its ability to promote glutathione production, as well as by supporting the body’s...
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Glutathione, 500 mg, 60 Veg Capsules (Now Foods)Glutathione, 500 mg, 60 Veg Capsules (Now Foods)

English version

Amino Acids Antioxidants TBSS ID:
Glutathione, 500 mg, 60 Veg Capsules (Now Foods) contains amoung others Silibinin.

Glutathione, 500 mg, 60 Veg Capsules (Now Foods) is available in many countries around the world.

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Glutathione is a small peptide molecule composed of three amino acids: cysteine, glutamic acid, and glycine. It is produced by every cell of the body, with especially high levels in the liver. Glutathione is critical for healthy immune system function and is necessary for proper detoxification...
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Glutathione, 500 mg, 30 Veg Capsules (Now Foods)Glutathione, 500 mg, 30 Veg Capsules (Now Foods)

English version

Amino Acids Antioxidants TBSS ID:
Glutathione, 500 mg, 30 Veg Capsules (Now Foods) contains amoung others Silibinin.

Glutathione, 500 mg, 30 Veg Capsules (Now Foods) is available in many countries around the world.

If you are not in The United Kingdom (GB)
>> Select Your Country <<

 

Learn More (GB)
Glutathione is a small peptide molecule composed of three amino acids: cysteine, glutamic acid, and glycine. It is produced by every cell of the body, with especially high levels in the liver. Glutathione is critical for healthy immune system function and is necessary for proper detoxification...
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If you know of any other quality supplement that has not been yet classified by us, please contact us and we will gladly consider adding it to our catalogue.


Silibinin

TBS Ingredient ID (TBSI ID):
Name
Silibinin
Synonyms:
Silybin, Silibinin A, Silymarin, Silymarine, Silymarin I, Silybin A, Flavobin, Silibinine, Silliver, Silybine, Silibininum, Silibinina, Legalon, Silimarin
Chemical Formula:
C25H22O10
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard		SEBFKMXJBCUCAI-HKTJVKLFSA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)		22888-70-6
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number		245-302-5
NSC Number: 651520
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
Show: Silibinin - description from ChEBI
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
3DMet:
3DMET is a database collecting three-dimensional structures of natural metabolites.
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
Show: Silibinin - description from DrugBank
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier