Brain Actives

Brain Actives – Ingredientes

• Performance & Energy Booster
  
• Theacrine – TeaCrine® (125 Mg)
  • TeaCrine® (C₉H₁₂N₄O₃)
    TeaCrine® liberta o seu máximo potencial. É extremamente eficaz em combinação com cafeína. Não causa irritação nem choque de cafeína. Independentemente de esperar apoio no esforço mental ou durante o treino no ginásio, o TeaCrine® ajuda-o com a mesma eficácia.
    TeaCrine®: Theacrine, Tetramethyluric Acid, Temurin, Temorine, 1,3,7,9-Tetramethyluric Acid, Tetramethyl Uric Acid, PubChem CID: 75324, Chemical Abstracts Service: CAS: 2309-49-1, ChemIDplus: 2309-49-1, FDA Substance Registration System – Unique Ingredient Identifier: UNII: EJ939L81MY, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISAA22B0, References: Brain / Mental Clarity: ZIEGENFUSS, Tim N.; et al. A Two-Part Approach to Examine the Effects of Theacrine (TeaCrine®) Supplementation on Oxygen Consumption, Hemodynamic Responses, and Subjective Measures of Cognitive and Psychometric Parameters. Journal of dietary supplements, 2017, 14.1: 9-24. PMID:27164220, TAYLOR, Lem; et al. Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use. Journal of the International Society of Sports Nutrition, 2016, 13.1: 2. PMID:26766930.
    
• Natural Caffeine Anhydrous (150 Mg)
  • Cafeína (C₈H₁₀N₄O₂)
    Cafeína: acelera o tempo de resposta, reduz a fadiga, aumenta a resistência física, ajuda a aumentar a vigilância.
    Cafeína: Caffeine, 1,3,7-Trimethylxanthine, Thein,
    PubChem CID: 2519,
    Chemical Abstracts Service: CAS: 58-08-2,
    ChemIDplus: 58-08-2,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: N06BC01,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2C8E40,
    References:
    Brain / Mental Clarity: BELLO, Marissa L.; et al. The effects of TeaCrine® and caffeine on endurance and cognitive performance during a simulated match in high-level soccer players. Journal of the International Society of Sports Nutrition, 2019, 16.1: 20. PMID:30999897, DIETZ, Christina; DEKKER, Matthijs Effect of Green Tea Phytochemicals on Mood and Cognition. Current pharmaceutical design, 2017, 23.19: 2876-2905. PMID:28056735.
    
• Cognitive & Nootropic Complex
  
• Ashwagandha Root Extract [5% Withanolides] – KSM-66® (300 Mg)
  • Ashwagandha (Withania Somnifera)
    Ashwagandha: melhora a memória, aumenta a capacidade de aprendizagem, apoia a capacidade cognitiva, ajuda a reduzir o stress. Species: Withania Somnifera,
    Family: Solanaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH9BA3C0,
    References:
    Brain / Mental Clarity: ANDRADE, Chittaranjan; et al. A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera. Indian journal of psychiatry, 2000, 42.3: 295. PMID:21407960, YENISETTI, Sarat; et al. Neuropharmacological Properties of Withania somnifera – Indian Ginseng: An Overview on Experimental Evidence with Emphasis on Clinical Trials and Patents. Recent patents on CNS drug discovery, 2015, 10.2: 204-215. PMID:27316579,
    Stress / Relaxation: CHANDRASEKHAR, K.; KAPOOR, Jyoti; ANISHETTY, Sridhar A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian journal of psychological medicine, 2012, 34.3: 255. PMID:23439798, SALVE, Jaysing; et al. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus, 2019, 11.12: e6466. PMID:32021735.
    
    
  • KSM-66®
    KSM-66®: KSM-66®, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISAA49C0, References: Sports Nutrition: CHOUDHARY, Bakhtiar; SHETTY, A.; LANGADE, Deepak G. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. Ayu, 2015, 36.1: 63. PMID:26730141.
    
• Bacopa Monnieri Herb Extract [50% Bacosides] – Bacopin® (150 Mg)
  • Bacopa Monnieri (Bacopa Monnieri)
    Ajuda a absorver o conhecimento, reforça a capacidade de concentração, melhora a função cerebral, melhora as funções cognitivas. A erva indiana Bacopa Monnieri contém compostos chamados bacosides que ajudam a reparar neurônios danificados e ajudam a promover o crescimento do nervo novo. Isso melhora a comunicação dos neurônios com o cérebro, ajudando a melhorar a função cognitiva e o desempenho mental. Species: Bacopa Monnieri,
    Family: Plantaginaceae,
    Domain: Plantae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH358EF0,
    References:
    Brain / Mental Clarity: MCPHEE, G. M.; DOWNEY, L. A.; NOBLE, A.; STOUGH, C. Cognitive training and Bacopa monnieri: Evidence for a combined intervention to alleviate age associated cognitive decline. Medical hypotheses, 2016, 95: 71-76. PMID:27692172, MORGAN, A.; STEVENS, J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. The journal of alternative and complementary medicine, 2010, 16.7: 753-759. PMID:20590480.
    
    
  • Bacopin®
    Bacopin®: Bacopin®, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISAA70D0.
    
• Gotu Kola Leaf Extract [8% Triterpenes] – Centellin® (50 Mg)
  • Gotu Kola (Centella Asiatica)
    Gotu Kola: nootrópico conhecido, revitaliza o cérebro e o sistema nervoso, aumenta a capacidade de atenção, melhora a memória a longo prazo. Species: Centella Asiatica,
    Family: Apiaceae Mackinlayaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH4FA6A0,
    References:
    Brain / Mental Clarity: PUTTARAK, Panupong; et al. Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis. Scientific reports, 2017, 7.1: 10646. PMID:28878245, SHINOMOL, G. K.; et al. Exploring the Role of “Brahmi” (Bacopa monnieri and Centella asiatica) in Brain Function and Therapy. Recent patents on endocrine, metabolic & immune drug discovery, 2011, 5.1: 33-49. PMID:22074576,
    Cardiovascular Support: RAZALI, Nur Nadia Mohd; NG, Chin Theng; FONG, Lai Yen Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review. Planta medica, 2019, 85.16: 1203-1215. PMID:31539918.
    
    
  • Centellin®
    Centellin®: Centellin®, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2D2A80.
    
  • Triterpenes (C₃₀H₄₈)
    Triterpenes: Triterpenes, Triterpene, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS391160.
    
    • Madecassol (C₄₈H₇₈O₁₉)
      Madecassol: Madecassol, Asiaticoside, Centelase, Blastostimulina,
      PubChem CID: 11954171,
      Chemical Abstracts Service: CAS: 16830-15-2,
      ChemIDplus: 16830-15-2,
      FDA Substance Registration System – Unique Ingredient Identifier: UNII: PKO39VY215,
      The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISEDBB60.
      
    • Brahmoside
      Brahmoside: Brahmoside, Brahminoside, PubChem CID: 395762, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED9450.
      
    • Asiatic Acid (C₃₀H₄₈O₅)
      Asiatic Acid: Asiatic Acid, Asiantic Acid, Dammarolic Acid,
      PubChem CID: 119034,
      Chemical Abstracts Service: CAS: 464-92-6,
      ChemIDplus: 464-92-6,
      FDA Substance Registration System – Unique Ingredient Identifier: UNII: 9PA5A687X5,
      The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED6D40.
      
    • Madecassic Acid (C₃₀H₄₈O₆)
      Madecassic Acid: Madecassic Acid, Brahmic Acid, 6Beta-Hydroxyasiatic Acid,
      PubChem CID: 73412,
      Chemical Abstracts Service: CAS: 18449-41-7,
      ChemIDplus: 18449-41-7,
      FDA Substance Registration System – Unique Ingredient Identifier: UNII: M7O1N24J82,
      The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED4630.
      
• Black Pepper Fruit Extract [95% Piperine] – BioPerine® (5 Mg)
  • Black Pepper (Piper Nigrum)Species: Piper Nigrum,
    Family: Piperaceae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2CB550,
    References:
    Brain / Mental Clarity: JOSHI, Hanumanthachar; PARLE, Milind Effects of piperine on memory and behavior mediated via monoamine neurotransmiters. Journal of Traditional Medicines, 2005, 22.2+ 3: 39-43., NEWERLI-GUZ, Joanna; ŚMIECHOWSKA, Maria Assessment of the contents of piperine in black pepper berries Piper nigrum L. Bromatologia i Chemia Toksykologiczna, 2009, XLII: 827–830..
    
    
  • BioPerine®
    O BioPerine® é uma forma inovadora da piperina, livre de substâncias químicas utilizadas para cultivo de plantas, tais como adubos, concentrados, fortificantes, pesticidas ou outros produtos de proteção de plantas. A sua segurança de uso foi comprovada pelos estudos da Autoridade Europeia para a Segurança dos Alimentos (EFSA). Graças à melhor, em comparação com o estado convencional, absorção e uso desta forma, observa-se um aumento significativo de absorção de outros ingredientes valiosos deste suplemento. Isso faz com que haja até 30 vezes maiores efeitos do seu funcionamento. Além disso, o BioPerine® contém mais piperina do que extrato de pimenta preta, o que adicionalmente intensifica a eficácia do produto.
    BioPerine®: BioPerine®,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS28E4C0.
    
  • Piperine (C₁₇H₁₉NO₃)
    Piperine: Piperine, Bioperine, Piperin, 1-Piperoylpiperidine, Piperoylpiperidine, 1-Piperylpiperidine,
    PubChem CID: 638024,
    Chemical Abstracts Service: CAS: 94-62-2,
    ChemIDplus: 94-62-2,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS395F80,
    References:
    Brain / Mental Clarity: JOSHI, Hanumanthachar; PARLE, Milind Effects of piperine on memory and behavior mediated via monoamine neurotransmiters. Journal of Traditional Medicines, 2005, 22.2+ 3: 39-43..
    
• Neuro Vita-Min Blend
  
• Vitamin B6 (14 Mg)
  • Vitamina B6 (piridoxina) (C₈H₁₁NO₃)
    Necessária para a biossíntese de vários neurotransmissores, incluindo dopamina, serotonina, e GABA (ácido gama-aminobutírico). O CILTEP contém uma forma metabolicamente ativa de vitamina B6 (Piridoxal-5-Fosfato) de maneira a garantir uma atividade cognitiva otimizada.
    Vitamina B6 (piridoxina): Pyridoxine, Gravidox, Pyridoxol, Vitamin B6,
    PubChem CID: 1054,
    Chemical Abstracts Service: CAS: 65-23-6,
    ChemIDplus: 65-23-6,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA02,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: KV2JZ1BI6Z,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS264CB0,
    References:
    Cardiovascular Support: FRISO, Simonetta; et al. Vitamin B6 and Cardiovascular Disease. In: Water Soluble Vitamins. Springer, Dordrecht, 2012, 56: 265-290. PMID:22116704, JEON, Jimin; PARK, Kyong Dietary Vitamin B 6 Intake Associated With a Decreased Risk of Cardiovascular Disease: A Prospective Cohort Study. Nutrients, 2019, 11.7: 1484. PMID:31261898,
    Brain / Mental Clarity: BOURRE, Jean-Marie Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. Journal of Nutrition Health and Aging, 2006, 10.5: 377. PMID:17066209, RAMOS, Rúben J.; et al. Vitamin B6 Is Essential for Serine De Novo Biosynthesis. Journal of inherited metabolic disease, 2017, 40.6: 883-891. PMID:28801717,
    Stress / Relaxation: POUTEAU, Etienne; et al. Superiority of Magnesium and Vitamin B6 Over Magnesium Alone on Severe Stress in Healthy Adults With Low Magnesemia: A Randomized, Single-Blind Clinical Trial. PloS one, 2018, 13.12: e0208454. PMID:30562392, KELLY, Gregory S. Nutritional and Botanical Interventions to Assist With the Adaptation to Stress. Alternative medicine review: a journal of clinical therapeutic, 1999, 4.4: 249-265. PMID:10468649,
    Sports Nutrition: MANORE, Melinda M. Vitamin B6 and Exercise. International Journal of Sport Nutrition and Exercise Metabolism, 1994, 4.2: 89-103. PMID:8054964.
    
• Vitamin B12 (25 μg)
  • Vitamina B12 (cobalamina, cianocobalamina) (C₆₃H₈₈CoN₁₄O₁₄P)
    Vitamina B12 (cobalamina, cianocobalamina): Cyanocobalamin, Vitamin B12, Cobalamin, Crystamine, Anacobin,
    PubChem CID: 5311498,
    Chemical Abstracts Service: CAS: 68-19-9,
    ChemIDplus: 68-19-9,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: B03BA01,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: P6YC3EG204,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS30D400,
    References:
    Brain / Mental Clarity: SMITH, A. David; WARREN, Martin J.; REFSUM, Helga Vitamin B12. In: Advances in food and nutrition research. Academic Press, 2018, 2018: 215-279. PMID:29477223, TANGNEY, C. C.; AGGARWAL, N. T.; LI, H.; WILSON, R. S.; DECARLI, C.; EVANS, D. A.; MORRIS, M. C. Vitamin B12, cognition, and brain MRI measures: a cross-sectional examination. Neurology, 2011, 77.13: 1276-1282. PMID:21947532,
    Stress / Relaxation: KELLY, Gregory S. Nutritional and Botanical Interventions to Assist With the Adaptation to Stress. Alternative medicine review: a journal of clinical therapeutic, 1999, 4.4: 249-265. PMID:10468649.
    
• Pantothenic Acid (15 Mg)
  • Vitamina B5 (ácido pantotênico) (C₉H₁₇NO₅)
    Vitamina B5 (ácido pantotênico): D-Pantothenic Acid, Vitamin B5, Pantothenic Acid, Pantothenate,
    PubChem CID: 6613,
    Chemical Abstracts Service: CAS: 79-83-4,
    ChemIDplus: 79-83-4,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA31,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 19F5HK2737,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS26C1E0,
    References:
    Brain / Mental Clarity: KENNEDY, David O. B Vitamins and the Brain: Mechanisms, Dose and Efficacy–A Review. Nutrients, 2016, 8.2: 68. PMID:26828517,
    Stress / Relaxation: KELLY, Gregory S. Nutritional and Botanical Interventions to Assist With the Adaptation to Stress. Alternative medicine review: a journal of clinical therapeutic, 1999, 4.4: 249-265. PMID:10468649.
    
• Magnesium – Aquamin™ Mg (75 Mg)
  • Magnésio (Mg)
    Magnésio: Magnesium, PubChem CID: 5462224, Chemical Abstracts Service: CAS: 7439-95-4, ChemIDplus: 7439-95-4, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS371590, References: Brain / Mental Clarity: BOURRE, Jean-Marie Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. Journal of Nutrition Health and Aging, 2006, 10.5: 377. PMID:17066209, HUSKISSON, E.; MAGGINI, S.; RUF, M. The influence of micronutrients on cognitive function and performance. Journal of international medical research, 2007, 35.1: 1-19. PMID:17408051, Stress / Relaxation: POUTEAU, Etienne; et al. Superiority of Magnesium and Vitamin B6 Over Magnesium Alone on Severe Stress in Healthy Adults With Low Magnesemia: A Randomized, Single-Blind Clinical Trial. PloS one, 2018, 13.12: e0208454. PMID:30562392, Sports Nutrition: CINAR, Vedat; et al. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion. Biological trace element research, 2011, 140.1: 18-23. PMID:20352370.