Digestive Health

Digestive Health - References & External links

The references to scientific articles about Digestive Health are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• The properties of Amylase boosting Digestive Health:
  • DHITAL, Sushil; et al. Mechanisms of starch digestion by α-amylase-Structural basis for kinetic properties. Critical reviews in food science and nutrition, 2017, 57.5: 875-892. PMID:25751598
  • FREITAS, Daniela; et al. The important role of salivary α-amylase in the gastric digestion of wheat bread starch. Food & function, 2018, 9.1: 200-208. PMID:29260815
• The properties of Protease boosting Digestive Health:
  • WHITCOMB, David C.; LOWE, Mark E. Human pancreatic digestive enzymes. Digestive diseases and sciences, 2007, 52.1: 1-17. PMID:17205399
• The properties of Berberine boosting Digestive Health:
  • XU, Xinmei; et al. Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence. Biomedicine & Pharmacotherapy, 2021, 133: 110984. PMID:33186794
  • CICERO, Arrigo F. G.; BAGGIONI, Alessandra. Berberine and Its Role in Chronic Disease. Anti-inflammatory Nutraceuticals and Chronic Diseases, 2016, 2016: 27-45. PMID:27671811
  • CALICETI, Cristiana; et al. Berberine: New Insights from Pharmacological Aspects to Clinical Evidences in the Management of Metabolic Disorders. Current Medicinal Chemistry, 2016, 23.14: 1460-1476. PMID:27063256
  • SCAZZOCCHIO, Francesca; et al. Antibacterial activity of Hydrastis canadensis extract and its major isolated alkaloids. Planta medica, 2001, 67.06: 561-564. PMID:11509983
• The properties of Selenium boosting Digestive Health:
  • KUDVA, Avinash K.; SHAY, Ashley E.; PRABHU, K. Sandeep. Selenium and Inflammatory Bowel Disease. American Journal of Physiology-Gastrointestinal and Liver Physiology, 2015, 309.2: G71-G77. PMID:26045617
• The properties of Hydrastis Canadensis boosting Digestive Health:
  • SCAZZOCCHIO, Francesca; et al. Antibacterial activity of Hydrastis canadensis extract and its major isolated alkaloids. Planta medica, 2001, 67.06: 561-564. PMID:11509983
• The properties of Zingiber Officinale boosting Digestive Health:
  • HANIADKA, Raghavendra; et al. A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe). Food & Function, 2013, 4.6: 845-855. PMID:23612703
  • PETERSON, Christine T.; et al. Prebiotic Potential of Culinary Spices Used to Support Digestion and Bioabsorption. Evidence-Based Complementary and Alternative Medicine, 2019, 6.2: 8973704. PMID:31281405
• The properties of Mentha X Piperita boosting Digestive Health:
  Peppermint: A spasmolytic effect, Refreshes breath, Supports the stomach and intestines function.
  • CHUMPITAZI, Bruno P.; KEARNS, G. L.; SHULMAN, Robert J. Review article: the physiological effects and safety of peppermint oil and its efficacy in irritable bowel syndrome and other functional disorders. Alimentary pharmacology & therapeutics, 2018, 47.6: 738-752. PMID:29372567
    CONCLUSION: Peppermint oil is a natural product which affects physiology throughout the gastrointestinal tract, has been used successfully for several clinical disorders, and appears to have a good safety profile.
  • MERAT, Shahin; et al. The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome. Digestive diseases and sciences, 2010, 55.5: 1385-1390. PMID:19507027
  • CAPPELLO, G.; et al. Peppermint oil (Mintoil®) in the treatment of irritable bowel syndrome: A prospective double blind placebo-controlled randomized trial. Digestive and liver disease, 2007, 39.6: 530-536. PMID:17420159
    CONCLUSION: A 4 weeks treatment with peppermint oil improves abdominal symptoms in patients with irritable bowel syndrome.
  • CASH, Brooks D.; EPSTEIN, Michael S.; SHAH, Syed M. A Novel Delivery System of Peppermint Oil Is an Effective Therapy for Irritable Bowel Syndrome Symptoms. Digestive diseases and sciences, 2016, 61.2: 560-571. PMID:26319955
    CONCLUSIONS: A novel PO formulation designed for sustained release in the small intestine is a safe, effective treatment capable of providing rapid relief of IBS symptoms.
• The properties of Piper Nigrum boosting Digestive Health:
  • ZHANG, Chi; et al. Antioxidant, hepatoprotective and antifungal activities of black pepper (Piper nigrum L.) essential oil. Food Chemistry, 2021, 346: 128845. PMID:33387832
  • PETERSON, Christine T.; et al. Prebiotic Potential of Culinary Spices Used to Support Digestion and Bioabsorption. Evidence-Based Complementary and Alternative Medicine, 2019, 6.2: 8973704. PMID:31281405
• The properties of Centella Asiatica boosting Digestive Health:
  • LI, Huibiao; et al. Ethanol extract of Centella asiatica alleviated dextran sulfate sodium-induced colitis: Restoration on mucosa barrier and gut microbiota homeostasis. Journal of Ethnopharmacology, 2021, 267: 113445. PMID:33022343
    Conclusions: CA displayed the anti-inflammatory activity against the DSS-induced colitis, which would possibly rely on the restoration on mucosa barrier and gut microbiota homeostasis, highlights a promising application of C. asiatica in the clinical treatment of UC.
  • WANNASARIT, Saowanee; et al. Raft-forming gastro-retentive formulations based on Centella asiatica extract-solid dispersions for gastric ulcer treatment. European Journal of Pharmaceutical Sciences, 2020, 143: 105204. PMID:31870812
• The properties of Carvacrol boosting Digestive Health:
  • KACHUR, Karina; SUNTRES, Zacharias. The antibacterial properties of phenolic isomers, carvacrol and thymol. Critical reviews in food science and nutrition, 2020, 60.18: 3042-3053. PMID:31617738
• The properties of Cinnamomum Verum boosting Digestive Health:
  Cinnamon: Has an antioxidant effect, Helps to maintain fresh breath, Supports digestive processes.
  • RANASINGHE, Priyanga; et al. Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review. BMC complementary and alternative medicine, 2013, 13.1: 1-10. PMID:24148965
    Conclusions: The available in-vitro and in-vivo evidence suggests that CZ has many beneficial health effects. However, since data on humans are sparse, randomized controlled trials in humans will be necessary to determine whether these effects have public health implications.
  • HAYWARD, Nicholas J.; et al. Cinnamon Shows Antidiabetic Properties that Are Species-Specific: Effects on Enzyme Activity Inhibition and Starch Digestion. Plant Foods for Human Nutrition, 2019, 74.4: 544-552. PMID:31372918
• The properties of Achillea Millefolium boosting Digestive Health:
  • ZENGIN, Gokhan; et al. Shedding light on the biological and chemical fingerprints of three Achillea species (A. biebersteinii, A. millefolium and A. teretifolia). Food & function, 2017, 8.3: 1152-1165. PMID:28174780
  • MOHAMMADHOSSEINI, Majid; SARKER, Satyajit D.; AKBARZADEH, Abolfazl. Chemical composition of the essential oils and extracts of Achillea species and their biological activities: A review. Journal of ethnopharmacology, 2017, 199: 257-315. PMID:28179115
    CONCLUSIONS: General correlations between the ethnopharmacological uses and medicinal properties identified through systematic research have been observed. Some of the medicinal properties could also be linked to the phytochemicals present in this genus. The findings of the studied reports in this review article represent therapeutic characteristics of Achillea species and account for their significant impact on the current and future modern medicine.
  • CANDAN, Ferda; et al. Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp. millefolium Afan.(Asteraceae). Journal of ethnopharmacology, 2003, 87.2-3: 215-220. PMID:12860311
  • EL-KALAMOUNI, Chaker; et al. Antioxidant and Antimicrobial Activities of the Essential Oil of Achillea millefolium L. Grown in France. Medicines, 2017, 4.2: 30. PMID:28930245
    Conclusion: The EO composition of A. millefolium chemotype located in France was studied. The EO of the A. millefolium wild plant grown in France is quite an effective antioxidant in sunflower oil oxidation; it also possesses inhibitory effects against famous bacteria and fungi.
• The properties of Syzygium Aromaticum boosting Digestive Health:
  • CHAIEB, Kamel; et al. The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata (Syzigium aromaticum L. Myrtaceae): a short review. Phytotherapy research, 2007, 21.6: 501-506. PMID:17380552
  • LIU, Qing; et al. Antibacterial and antifungal activities of spices. International journal of molecular sciences, 2017, 18.6: 1283. PMID:28621716
• The properties of Centaurium Erythraea boosting Digestive Health:
  • ŠILER, Branislav; et al. Centauries as underestimated food additives: Antioxidant and antimicrobial potential. Food chemistry, 2014, 147: 367-376. PMID:24206732
• The properties of Levisticum Officinale boosting Digestive Health:
  • MIRAN, Mansour; et al. Characterization and Antibacterial Activity of Phthalides from the Roots of the Medicinal Herb Levisticum officinale W.D.J. Koch. Iranian Journal of Pharmaceutical Research: IJPR, 2020, 19.2: 182. PMID:33224223
• The properties of Omega-3 Acids boosting Digestive Health:
  • COSTANTINI, Lara; et al. Impact of Omega-3 Fatty Acids on the Gut Microbiota. International journal of molecular sciences, 2017, 18.12: 2645. PMID:29215589
• The properties of Apium Graveolens boosting Digestive Health:
  • HEDAYATI, Narges; et al. Beneficial effects of celery (Apium graveolens) on metabolic syndrome: A review of the existing evidences. Phytotherapy Research, 2019, 33.12: 3040-3053. PMID:31464016
• The properties of Rutin boosting Digestive Health:
  • KIM, Heejung; et al. Metabolic and Pharmacological Properties of Rutin, a Dietary Quercetin Glycoside, for Treatment of Inflammatory Bowel Disease. Pharmaceutical research, 2005, 22.9: 1499-1509. PMID:16132362
    Conclusions: Our data suggest that rutin acted as a quercetin deliverer to the large intestine and its anti-inflammatory action in TNBS-induced colitis rats may be through quercetin-mediated inhibition of TNF-alpha-induced NFkappaB activation.
• The properties of Histidine boosting Digestive Health:
  • PETERSON, Johnny W.; et al. Anti-inflammatory and Antisecretory Potential of Histidine in Salmonella-challenged Mouse Small Intestine. Laboratory investigation; a journal of technical methods and pathology, 1998, 78.5: 523-534. PMID:9605177
• The properties of Lactase boosting Digestive Health:
  • FORSGåRD, Richard A. Lactose Digestion in Humans: Intestinal Lactase Appears to Be Constitutive Whereas the Colonic Microbiome Is Adaptable. The American journal of clinical nutrition, 2019, 110.2: 273-279. PMID:31175813
  • LUKITO, Widjaja; et al. From 'Lactose Intolerance' to 'Lactose Nutrition'. Asia Pacific journal of clinical nutrition, 2015, 24.Supplement: S1. PMID:26715078
• The properties of Boswellia Serrata boosting Digestive Health:
  • MADISCH, Ahmed; et al. Boswellia Serrata Extract for the Treatment of Collagenous Colitis. A Double-Blind, Randomized, Placebo-Controlled, Multicenter Trial. International journal of colorectal disease, 2007, 22.12: 1445-1451. PMID:17764013
    Conclusions: Our study suggests that BSE might be clinically effective in patients with collagenous colitis. Larger trials are clearly necessary to establish the clinical efficacy of BSE.
• The properties of Probiotics boosting Digestive Health:
  Probiotics promote and help to maintain beneficial microbiota composition of the gastrointestinal tract ecosystem and have a positive impact on the host's health.
  • SZAJEWSKA, Hania; KONARSKA, Zofia; KOłODZIEJ, Maciej. Probiotic Bacterial and Fungal Strains: Claims With Evidence. Digestive diseases, 2016, 34.3: 251-259. PMID:27028756
    Conclusions: The evidence on bacterial and yeast probiotics has considerably expanded during recent years. Accumulated data allow one to make informed decisions about the effectiveness of probiotics and about how to reduce the use of those without proven efficacy.
  • PUGH, Jamie N.; et al. Four Weeks of Probiotic Supplementation Reduces GI Symptoms During a Marathon Race. European journal of applied physiology, 2019, 119.7: 1491-1501. PMID:30982100
    Conclusion: Probiotics supplementation was associated with a lower incidence and severity of GI symptoms in marathon runners, although the exact mechanisms are yet to be elucidated. Reducing GI symptoms during marathon running may help maintain running pace during the latter stages of racing.
  • RADKE, Michael; et al. Starter Formula Enriched in Prebiotics and Probiotics Ensures Normal Growth of Infants and Promotes Gut Health: A Randomized Clinical Trial. Pediatric research, 2017, 81.4: 622-631. PMID:28002391
    Conclusion: An infant formula enriched with bovine milk-derived oligosaccharide and B. lactis supports normal infant growth, is well tolerated and improves intestinal health markers. No differences in diarrhea and febrile infection incidence were found in the population studied.
• The properties of Inulin boosting Digestive Health:
  Commonly, inulin is used as a prebiotic, fat replacer, sugar replacer, texture modifier and for the development of functional foods in order to improve health due to its beneficial role in gastric health.
  • MCRORIE JR, Johnson W.; MCKEOWN, Nicola M. Understanding the Physics of Functional Fibers in the Gastrointestinal Tract: An Evidence-Based Approach to Resolving Enduring Misconceptions About Insoluble and Soluble Fiber. Journal of the Academy of Nutrition and Dietetics, 2017, 117.2: 251-264. PMID:27863994
  • RAMIREZ-FARIAS, Carlett; et al. Effect of Inulin on the Human Gut Microbiota: Stimulation of Bifidobacterium Adolescentis and Faecalibacterium Prausnitzii. British Journal of Nutrition, 2008, 101.4: 541-550. PMID:18590586
• The properties of Lactobacillus Rhamnosus boosting Digestive Health:
  Health effects are well documented including the prevention and treatment of gastro-intestinal infections and diarrhea, and stimulation of immune responses that promote vaccination or even prevent certain allergic symptoms.
  • PACE, M.; QUARTARONE, G. Probiotics in Digestive Diseases: Focus on Lactobacillus GG. Minerva gastroenterologica e dietologica, 2015, 61.4: 273-292. PMID:26657927
  • SEGERS, Marijke E.; LEBEER, Sarah. Towards a Better Understanding of Lactobacillus Rhamnosus GG--host Interactions. In: Microbial cell factories. BioMed Central, 2014, 2014: S7. PMID:25186587
  • KONIECZNA, Corinna; SłODZIńSKI, Michał; SCHMIDT, Marcin T. Exopolysaccharides Produced by Lactobacillus rhamnosus KL 53A and Lactobacillus casei Fyos Affect Their Adhesion to Enterocytes. Polish journal of microbiology, 2018, 67.3: 273-281. PMID:30451443
  • RUNGSRI, P.; et al. Effect of Fermented Milk Containing Lactobacillus Rhamnosus SD11 on Oral Microbiota of Healthy Volunteers: A Randomized Clinical Trial. Journal of dairy science, 2017, 100.10: 7780-7787. PMID:28803012
  • WAN, Murphy Lam‐Yim; et al. Effects of Lactobacillus Rhamnosus GG and Escherichia Coli Nissle 1917 Cell-Free Supernatants on Modulation of Mucin and Cytokine Secretion on Human Intestinal Epithelial HT29-MTX Cells. Journal of food science, 2018, 83.7: 1999-2007. PMID:29863797
  • JEFFREY, Michael P.; et al. Suppression of Intestinal Epithelial Cell Chemokine Production by Lactobacillus rhamnosus R0011 and Lactobacillus helveticus R0389 Is Mediated by Secreted Bioactive Molecules. Frontiers in immunology, 2018, 9: 2639. PMID:30524427
  • JIANG, Qingru; et al. Interactions Between Lactobacillus Rhamnosus GG and Oral Micro-Organisms in an in Vitro Biofilm Model. BMC microbiology, 2016, 16.1: 149. PMID:27405227
    Conclusions: To conclude, in this in vitro model L.GG successfully integrated in all oral biofilms, and reduced the counts of S. sanguinis and C. albicans and lowered the biofilm-forming ability of F. nucleatum, but only slightly reduced the adhesion of S. mutans. C. albicans significantly promoted the growth of L.GG.
  • CICENIA, Alessia; et al. Protective Role of Postbiotic Mediators Secreted by Lactobacillus Rhamnosus GG Versus Lipopolysaccharide-induced Damage in Human Colonic Smooth Muscle Cells. Journal of clinical gastroenterology, 2016, 50: S140-S144. PMID:27741159
    Conclusions: LGG-derived products are able to protect human SMCs from LPS-induced myogenic damage. Novel insights have been provided for the possibility that LGG-derived products could reduce the risk of progression to postinfective motor disorders.
  • SZAJEWSKA, Hania; KONARSKA, Zofia; KOłODZIEJ, Maciej. Probiotic Bacterial and Fungal Strains: Claims With Evidence. Digestive diseases, 2016, 34.3: 251-259. PMID:27028756
    Conclusions: The evidence on bacterial and yeast probiotics has considerably expanded during recent years. Accumulated data allow one to make informed decisions about the effectiveness of probiotics and about how to reduce the use of those without proven efficacy.
  • VERDENELLI, Maria Cristina; et al. Probiotic Properties of Lactobacillus Rhamnosus and Lactobacillus Paracasei Isolated From Human Faeces. European journal of nutrition, 2009, 48.6: 355-363. PMID:19365593
    Conclusions: Lactobacillus rhamnosus IMC 501 and L. paracasei IMC 502 present favourable strain-specific properties for their utilisation as probiotics in functional foods and the high adhesion ability of the L. rhamnosus IMC 501 and L. paracasei IMC 502 used in combination, confirmed by both in vitro and in vivo study, indicate that the two bacterial strains could be used as health-promoting bacteria.
  • SICHETTI, Marzia; et al. Anti-inflammatory Effect of Multistrain Probiotic Formulation (L. Rhamnosus, B. Lactis, and B. Longum). Nutrition, 2018, 53: 95-102. PMID:29674267
    Conclusion: The transwell model is an intriguing toll approach to studying the human epithelial barrier.
• The properties of Lactobacillus Acidophilus boosting Digestive Health:
  Lactobacillus Acidophilus, a type of friendly bacteria in the digestive system that supports the breakdown of food and absorption of nutrients for optimal digestive health.
  • RINGEL-KULKA, Tamar; et al. Probiotic Bacteria Lactobacillus Acidophilus NCFM and Bifidobacterium Lactis Bi-07 Versus Placebo for the Symptoms of Bloating in Patients With Functional Bowel Disorders: A Double-Blind Study. J Clin Gastroenterol, 2011, 45.6: 518-25. PMID:21436726
    Conclusions: L-NCFM and B-LBi07 twice a day improve symptoms of bloating in patients with FBDs. These data supports the role of intestinal bacteria in the pathophysiology of FBD and the role for probiotic bacteria in the management of these disorders.
  • DAS, Jugal Kishore; et al. Lactobacillus Acidophilus Binds to MUC3 Component of Cultured Intestinal Epithelial Cells With Highest Affinity. FEMS microbiology letters, 2016, 363.8: fnw050. PMID:26946538
  • KOOHESTANI, Mobin; et al. Effects of Cell-Free Supernatant of Lactobacillus acidophilus LA5 and Lactobacillus casei 431 Against Planktonic Form and Biofilm of Staphylococcus aureus. In: Veterinary Research Forum. Faculty of Veterinary Medicine, Urmia University, Urmia, Iran, 2018, 2018: 301. PMID:30713607
  • VEMURI, Ravichandra; et al. A Human Origin Strain Lactobacillus acidophilus DDS-1 Exhibits Superior in vitro Probiotic Efficacy in Comparison to Plant or Dairy Origin Probiotics. International journal of medical sciences, 2018, 15.9: 840. PMID:30008595
    Conclusion: Of the 4 strains tested, DDS-1 demonstrated superior survival rates, good adhesion capacity and strong immunomodulatory effect under different experimental conditions.
  • SANDERS, M. E.; KLAENHAMMER, T. R. Invited Review: The Scientific Basis of Lactobacillus Acidophilus NCFM Functionality as a Probiotic. Journal of dairy science, 2001, 84.2: 319-331. PMID:11233016
  • PUGH, Jamie N.; et al. Four Weeks of Probiotic Supplementation Reduces GI Symptoms During a Marathon Race. European journal of applied physiology, 2019, 119.7: 1491-1501. PMID:30982100
    Conclusion: Probiotics supplementation was associated with a lower incidence and severity of GI symptoms in marathon runners, although the exact mechanisms are yet to be elucidated. Reducing GI symptoms during marathon running may help maintain running pace during the latter stages of racing.
• The properties of Lactobacillus Delbrueckii boosting Digestive Health:
  • RUNGSRI, P.; et al. Effect of Fermented Milk Containing Lactobacillus Rhamnosus SD11 on Oral Microbiota of Healthy Volunteers: A Randomized Clinical Trial. Journal of dairy science, 2017, 100.10: 7780-7787. PMID:28803012
• The properties of Lactobacillus Casei boosting Digestive Health:
  • KONIECZNA, Corinna; SłODZIńSKI, Michał; SCHMIDT, Marcin T. Exopolysaccharides Produced by Lactobacillus rhamnosus KL 53A and Lactobacillus casei Fyos Affect Their Adhesion to Enterocytes. Polish journal of microbiology, 2018, 67.3: 273-281. PMID:30451443
  • KOOHESTANI, Mobin; et al. Effects of Cell-Free Supernatant of Lactobacillus acidophilus LA5 and Lactobacillus casei 431 Against Planktonic Form and Biofilm of Staphylococcus aureus. In: Veterinary Research Forum. Faculty of Veterinary Medicine, Urmia University, Urmia, Iran, 2018, 2018: 301. PMID:30713607
• The properties of Lactobacillus Helveticus boosting Digestive Health:
  • JEFFREY, Michael P.; et al. Suppression of Intestinal Epithelial Cell Chemokine Production by Lactobacillus rhamnosus R0011 and Lactobacillus helveticus R0389 Is Mediated by Secreted Bioactive Molecules. Frontiers in immunology, 2018, 9: 2639. PMID:30524427
• The properties of Lactobacillus Paracasei boosting Digestive Health:
  • VERDENELLI, Maria Cristina; et al. Probiotic Properties of Lactobacillus Rhamnosus and Lactobacillus Paracasei Isolated From Human Faeces. European journal of nutrition, 2009, 48.6: 355-363. PMID:19365593
    Conclusions: Lactobacillus rhamnosus IMC 501 and L. paracasei IMC 502 present favourable strain-specific properties for their utilisation as probiotics in functional foods and the high adhesion ability of the L. rhamnosus IMC 501 and L. paracasei IMC 502 used in combination, confirmed by both in vitro and in vivo study, indicate that the two bacterial strains could be used as health-promoting bacteria.
• The properties of Saccharomyces Boulardii boosting Digestive Health:
  • SZAJEWSKA, Hania; KONARSKA, Zofia; KOłODZIEJ, Maciej. Probiotic Bacterial and Fungal Strains: Claims With Evidence. Digestive diseases, 2016, 34.3: 251-259. PMID:27028756
    Conclusions: The evidence on bacterial and yeast probiotics has considerably expanded during recent years. Accumulated data allow one to make informed decisions about the effectiveness of probiotics and about how to reduce the use of those without proven efficacy.
• The properties of Bifidobacterium Animalis boosting Digestive Health:
  • GUYONNET, D.; et al. Effect of a Fermented Milk Containing Bifidobacterium Animalis DN-173 010 on the Health-Related Quality of Life and Symptoms in Irritable Bowel Syndrome in Adults in Primary Care: A Multicentre, Randomized, Double-Blind, Controlled Trial. Alimentary pharmacology & therapeutics, 2007, 26.3: 475-486. PMID:17635382
    Conclusions: This study suggests a beneficial effect of a probiotic food on discomfort HRQoL score and bloating in constipation-predominant IBS, and on stool frequency in subjects with
  • RINGEL-KULKA, Tamar; et al. Probiotic Bacteria Lactobacillus Acidophilus NCFM and Bifidobacterium Lactis Bi-07 Versus Placebo for the Symptoms of Bloating in Patients With Functional Bowel Disorders: A Double-Blind Study. J Clin Gastroenterol, 2011, 45.6: 518-25. PMID:21436726
    Conclusions: L-NCFM and B-LBi07 twice a day improve symptoms of bloating in patients with FBDs. These data supports the role of intestinal bacteria in the pathophysiology of FBD and the role for probiotic bacteria in the management of these disorders.
  • CHARNCHAI, Pattra; et al. Effects of the Food Manufacturing Chain on the Viability and Functionality of Bifidobacterium Animalis Through Simulated Gastrointestinal Conditions. PLoS One, 2016, 11.6: . PMID:27333286
  • SICHETTI, Marzia; et al. Anti-inflammatory Effect of Multistrain Probiotic Formulation (L. Rhamnosus, B. Lactis, and B. Longum). Nutrition, 2018, 53: 95-102. PMID:29674267
    Conclusion: The transwell model is an intriguing toll approach to studying the human epithelial barrier.
  • WEI, Meng; et al. Probiotic Bifidobacterium Animalis Subsp. Lactis Bi-07 Alleviates Bacterial Translocation and Ameliorates Microinflammation in Experimental Uraemia. Nephrology, 2014, 19.8: 500-506. PMID:24787732
    Conclusion: The probiotic B. animalis subsp. lactis Bi-07 alleviate bacterial translocation and ameliorate microinflammation through the recovery of intestinal mucosal integrity.
  • PUGH, Jamie N.; et al. Four Weeks of Probiotic Supplementation Reduces GI Symptoms During a Marathon Race. European journal of applied physiology, 2019, 119.7: 1491-1501. PMID:30982100
    Conclusion: Probiotics supplementation was associated with a lower incidence and severity of GI symptoms in marathon runners, although the exact mechanisms are yet to be elucidated. Reducing GI symptoms during marathon running may help maintain running pace during the latter stages of racing.
  • RADKE, Michael; et al. Starter Formula Enriched in Prebiotics and Probiotics Ensures Normal Growth of Infants and Promotes Gut Health: A Randomized Clinical Trial. Pediatric research, 2017, 81.4: 622-631. PMID:28002391
    Conclusion: An infant formula enriched with bovine milk-derived oligosaccharide and B. lactis supports normal infant growth, is well tolerated and improves intestinal health markers. No differences in diarrhea and febrile infection incidence were found in the population studied.
  • RAMIREZ-FARIAS, Carlett; et al. Effect of Inulin on the Human Gut Microbiota: Stimulation of Bifidobacterium Adolescentis and Faecalibacterium Prausnitzii. British Journal of Nutrition, 2008, 101.4: 541-550. PMID:18590586
  • SáNCHEZ, Borja; et al. Adaptation and Response of Bifidobacterium Animalis Subsp. Lactis to Bile: A Proteomic and Physiological Approach. Appl. Environ. Microbiol., 2007, 73.21: 6757-6767. PMID:17827318
• The properties of Bifidobacterium Bifidum boosting Digestive Health:
  • PUGH, Jamie N.; et al. Four Weeks of Probiotic Supplementation Reduces GI Symptoms During a Marathon Race. European journal of applied physiology, 2019, 119.7: 1491-1501. PMID:30982100
    Conclusion: Probiotics supplementation was associated with a lower incidence and severity of GI symptoms in marathon runners, although the exact mechanisms are yet to be elucidated. Reducing GI symptoms during marathon running may help maintain running pace during the latter stages of racing.
  • RAMIREZ-FARIAS, Carlett; et al. Effect of Inulin on the Human Gut Microbiota: Stimulation of Bifidobacterium Adolescentis and Faecalibacterium Prausnitzii. British Journal of Nutrition, 2008, 101.4: 541-550. PMID:18590586
• The properties of Bifidobacterium Longum boosting Digestive Health:
  • SICHETTI, Marzia; et al. Anti-inflammatory Effect of Multistrain Probiotic Formulation (L. Rhamnosus, B. Lactis, and B. Longum). Nutrition, 2018, 53: 95-102. PMID:29674267
    Conclusion: The transwell model is an intriguing toll approach to studying the human epithelial barrier.
  • RAMIREZ-FARIAS, Carlett; et al. Effect of Inulin on the Human Gut Microbiota: Stimulation of Bifidobacterium Adolescentis and Faecalibacterium Prausnitzii. British Journal of Nutrition, 2008, 101.4: 541-550. PMID:18590586
• The properties of Beta-Glucan boosting Digestive Health:
  • RIEDER, Anne; et al. At a High Dose Even Partially Degraded Beta-Glucan With Decreased Solubility Significantly Reduced the Glycaemic Response to Bread. Food & function, 2019, 10.3: 1529-1539. PMID:30785128
  • MCRORIE JR, Johnson W.; MCKEOWN, Nicola M. Understanding the Physics of Functional Fibers in the Gastrointestinal Tract: An Evidence-Based Approach to Resolving Enduring Misconceptions About Insoluble and Soluble Fiber. Journal of the Academy of Nutrition and Dietetics, 2017, 117.2: 251-264. PMID:27863994
• The properties of Plantago Ovata boosting Digestive Health:
  Psyllium Husks, a dietary fiber that helps soften the stool and facilitates normal, hassle-free bowel activity.
  • NG, S. C.; et al. Systematic Review: The Efficacy of Herbal Therapy in Inflammatory Bowel Disease. Alimentary pharmacology & therapeutics, 2013, 38.8: 854-863. PMID:23981095
    Conclusions: Randomised controlled trials of herbal therapy for the treatment of IBD show encouraging results but studies remain limited and heterogenous. Larger controlled studies with stricter endpoints and better-defined patient groups are required to obtain more conclusive results on the use of CAM therapies in IBD.
• The properties of Guar Gum boosting Digestive Health:
  • MCRORIE JR, Johnson W.; MCKEOWN, Nicola M. Understanding the Physics of Functional Fibers in the Gastrointestinal Tract: An Evidence-Based Approach to Resolving Enduring Misconceptions About Insoluble and Soluble Fiber. Journal of the Academy of Nutrition and Dietetics, 2017, 117.2: 251-264. PMID:27863994
• The properties of Dextrin boosting Digestive Health:
  • MCRORIE JR, Johnson W.; MCKEOWN, Nicola M. Understanding the Physics of Functional Fibers in the Gastrointestinal Tract: An Evidence-Based Approach to Resolving Enduring Misconceptions About Insoluble and Soluble Fiber. Journal of the Academy of Nutrition and Dietetics, 2017, 117.2: 251-264. PMID:27863994
• The properties of Idolax boosting Digestive Health:
  • MCRORIE JR, Johnson W.; MCKEOWN, Nicola M. Understanding the Physics of Functional Fibers in the Gastrointestinal Tract: An Evidence-Based Approach to Resolving Enduring Misconceptions About Insoluble and Soluble Fiber. Journal of the Academy of Nutrition and Dietetics, 2017, 117.2: 251-264. PMID:27863994
• The properties of Aloe Vera boosting Digestive Health:
  Aloe Vera: Supports detoxification, Helps to digest, Supports the transformation of xenobiotic substances. Aloe Vera Leaf is seen as a gentle laxative that may help cleanse the digestive system and colon of toxins, allowing the digestive tract to more efficiently break down the nutrients in foods.
  • NG, S. C.; et al. Systematic Review: The Efficacy of Herbal Therapy in Inflammatory Bowel Disease. Alimentary pharmacology & therapeutics, 2013, 38.8: 854-863. PMID:23981095
    Conclusions: Randomised controlled trials of herbal therapy for the treatment of IBD show encouraging results but studies remain limited and heterogenous. Larger controlled studies with stricter endpoints and better-defined patient groups are required to obtain more conclusive results on the use of CAM therapies in IBD.
  • SAHEBNASAGH, Adeleh; et al. Successful Treatment of Acute Radiation Proctitis With Aloe Vera: A Preliminary Randomized Controlled Clinical Trial. The Journal of Alternative and Complementary Medicine, 2017, 23.11: 858-865. PMID:28618234
    Conclusion: A substantial number of patients with radiation proctitis seem to benefit from therapy with Aloe vera 3% ointment.
  • GULLóN, Beatriz; et al. In Vitro Assessment of the Prebiotic Potential of Aloe Vera Mucilage and Its Impact on the Human Microbiota. Food & function, 2015, 6.2: 525-531. PMID:25504136
• The properties of Acemannan boosting Digestive Health:
  • QUEZADA, Maria Paz; et al. Acemannan and Fructans From Aloe Vera (Aloe Barbadensis Miller) Plants as Novel Prebiotics. Journal of agricultural and food chemistry, 2017, 65.46: 10029-10039. PMID:29072072
• The properties of Oenothera Biennis boosting Digestive Health:
  • NG, S. C.; et al. Systematic Review: The Efficacy of Herbal Therapy in Inflammatory Bowel Disease. Alimentary pharmacology & therapeutics, 2013, 38.8: 854-863. PMID:23981095
    Conclusions: Randomised controlled trials of herbal therapy for the treatment of IBD show encouraging results but studies remain limited and heterogenous. Larger controlled studies with stricter endpoints and better-defined patient groups are required to obtain more conclusive results on the use of CAM therapies in IBD.
• The properties of Artemisia Absinthium boosting Digestive Health:
  • NG, S. C.; et al. Systematic Review: The Efficacy of Herbal Therapy in Inflammatory Bowel Disease. Alimentary pharmacology & therapeutics, 2013, 38.8: 854-863. PMID:23981095
    Conclusions: Randomised controlled trials of herbal therapy for the treatment of IBD show encouraging results but studies remain limited and heterogenous. Larger controlled studies with stricter endpoints and better-defined patient groups are required to obtain more conclusive results on the use of CAM therapies in IBD.
  • SZOPA, Agnieszka; et al. Artemisia absinthium L.-Importance in the History of Medicine, the Latest Advances in Phytochemistry and Therapeutical, Cosmetological and Culinary Uses. Plants, 2020, 9.9: 1063. PMID:32825178
• The properties of Triticum Aestivum boosting Digestive Health:
  • NG, S. C.; et al. Systematic Review: The Efficacy of Herbal Therapy in Inflammatory Bowel Disease. Alimentary pharmacology & therapeutics, 2013, 38.8: 854-863. PMID:23981095
    Conclusions: Randomised controlled trials of herbal therapy for the treatment of IBD show encouraging results but studies remain limited and heterogenous. Larger controlled studies with stricter endpoints and better-defined patient groups are required to obtain more conclusive results on the use of CAM therapies in IBD.
• The properties of Andrographis Paniculata boosting Digestive Health:
  • NG, S. C.; et al. Systematic Review: The Efficacy of Herbal Therapy in Inflammatory Bowel Disease. Alimentary pharmacology & therapeutics, 2013, 38.8: 854-863. PMID:23981095
    Conclusions: Randomised controlled trials of herbal therapy for the treatment of IBD show encouraging results but studies remain limited and heterogenous. Larger controlled studies with stricter endpoints and better-defined patient groups are required to obtain more conclusive results on the use of CAM therapies in IBD.
• The properties of Scutellaria Baicalensis boosting Digestive Health:
  • XU, Guanglin. Treatment of Reflux Laryngopharyngitis With Modified Banxia Xiexin Tang (Pinellia Decoction for Draining the Heart)--A Report of 40 Cases. Journal of traditional Chinese medicine= Chung i tsa chih ying wen pan, 2006, 26.2: 127-131. PMID:16817279
    conclusion: The comparison of therapeutic effects on complication of laryngopharyngitis, GERD symptoms, and findings in gastroscope grading and laryngoscope (P < 0.05 or P < 0.01) demonstrated that the modified Pinellia Decoction for Draining the Heart was much more effective in treating laryngopahryngitis caused by gastroesophageal reflux.
• The properties of Lonicera Japonica boosting Digestive Health:
  • KU, Sae-Kwang; et al. Effect of Lonicerae Flos Extracts on Reflux Esophagitis With Antioxidant Activity. World journal of gastroenterology: WJG, 2009, 15.38: 4799. PMID:19824114
    Conclusion: The results suggest that antioxidant effects of LF could attenuate the severity of RE and prevent the esophageal mucosal damage, and validate its therapeutic use in esophageal reflux disease.
• The properties of Coptis Chinensis boosting Digestive Health:
  • YANG, Zhonghan; et al. Anti-Inflammatory Activities of a Chinese Herbal Formula IBS-20 In Vitro and In Vivo. Evidence-based Complementary and Alternative Medicine, 2012, 2012: . PMID:22461841
• The properties of Tripterygium Wilfordii boosting Digestive Health:
  • NG, S. C.; et al. Systematic Review: The Efficacy of Herbal Therapy in Inflammatory Bowel Disease. Alimentary pharmacology & therapeutics, 2013, 38.8: 854-863. PMID:23981095
    Conclusions: Randomised controlled trials of herbal therapy for the treatment of IBD show encouraging results but studies remain limited and heterogenous. Larger controlled studies with stricter endpoints and better-defined patient groups are required to obtain more conclusive results on the use of CAM therapies in IBD.
• The properties of Curcuma Longa boosting Digestive Health:
  • PRUCKSUNAND, Chaweewan; et al. Phase II Clinical Trial on Effect of the Long Turmeric (Curcuma Longa Linn) on Healing of Peptic Ulcer. Southeast Asian journal of tropical medicine and public health, 2001, 32.1: 208-215. PMID:11485087
  • BUNDY, Rafe; et al. Turmeric Extract May Improve Irritable Bowel Syndrome Symptomology in Otherwise Healthy Adults: A Pilot Study. Journal of Alternative & Complementary Medicine, 2004, 10.6: 1015-1018. PMID:15673996
    Conclusions: Turmeric may help reduce IBS symptomology. Placebo controlled trials are now warranted to confirm these findings.
  • HOLT, Peter R.; KATZ, Seymour; KIRSHOFF, Robert. Curcumin Therapy in Inflammatory Bowel Disease: A Pilot Study. Digestive diseases and sciences, 2005, 50.11: 2191-2193. PMID:16240238
  • HANAI, Hiroyuki; et al. Curcumin Maintenance Therapy for Ulcerative Colitis: Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial. Clinical Gastroenterology and Hepatology, 2006, 4.12: 1502-1506. PMID:17101300
    Conclusions: Curcumin seems to be a promising and safe medication for maintaining remission in patients with quiescent UC. Further studies on curcumin should strengthen our findings.
  • HENG, M. C. Y.; et al. Drug-induced Suppression of Phosphorylase Kinase Activity Correlates With Resolution of Psoriasis as Assessed by Clinical, Histological and Immunohistochemical Parameters. British Journal of Dermatology, 2000, 143.5: 937-949. PMID:11069500
    Conclusions: Our results demonstrate that drug-induced suppression of PhK activity is associated with resolution of psoriatic activity as assessed by clinical, histological and immunohistochemical criteria, and support the hypothesis that effective antipsoriatic activity may be achieved through modulation of PhK activity.
  • PETERSON, Christine T.; et al. Prebiotic Potential of Culinary Spices Used to Support Digestion and Bioabsorption. Evidence-Based Complementary and Alternative Medicine, 2019, 6.2: 8973704. PMID:31281405
• The properties of Curcumin boosting Digestive Health:
  • HOLT, Peter R.; KATZ, Seymour; KIRSHOFF, Robert. Curcumin Therapy in Inflammatory Bowel Disease: A Pilot Study. Digestive diseases and sciences, 2005, 50.11: 2191-2193. PMID:16240238
  • HANAI, Hiroyuki; et al. Curcumin Maintenance Therapy for Ulcerative Colitis: Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial. Clinical Gastroenterology and Hepatology, 2006, 4.12: 1502-1506. PMID:17101300
    Conclusions: Curcumin seems to be a promising and safe medication for maintaining remission in patients with quiescent UC. Further studies on curcumin should strengthen our findings.
• The properties of Colostrum boosting Digestive Health:
  Colostrum is a complex biological liquid that is richer in antimicrobial peptides, immune-regulating compounds and growth factors than the subsequent mature milk. The main functions of colostrum are to provide essential nutritional components, strengthen the natural defense system, modulate immune response, balance intestinal microbiota and enhance the growth and repair of several tissues. Colostrum-based supplements may play a complementary role to synthetic drugs in the prevention and treatment of various gastrointestinal disorders.
  • MENCHETTI, Laura; et al. Potential Benefits of Colostrum in Gastrointestinal Diseases. Front Bioscience (Scholar edition), 2016, 8.1: 331-51. PMID:27100711
• The properties of Thymol boosting Digestive Health:
  • KAJI, Izumi; KARAKI, Shin-ichiro; KUWAHARA, Atsukazu. Effects of luminal thymol on epithelial transport in human and rat colon. American Journal of Physiology-Gastrointestinal and Liver Physiology, 2011, 300.6: G1132-G1143. PMID:21372164
  • KACHUR, Karina; SUNTRES, Zacharias. The antibacterial properties of phenolic isomers, carvacrol and thymol. Critical reviews in food science and nutrition, 2020, 60.18: 3042-3053. PMID:31617738
  • KACHUR, Karina; SUNTRES, Zacharias. The antibacterial properties of phenolic isomers, carvacrol and thymol. Critical reviews in food science and nutrition, 2020, 60.18: 3042-3053. PMID:31617738
  • SIM, Jowenna Xiao Feng; et al. Antimicrobial activity of thyme oil, oregano oil, thymol and carvacrol against sensitive and resistant microbial isolates from dogs with otitis externa. Veterinary dermatology, 2019, 30.6: 524-e159. PMID:31566822
    Conclusions: Oregano oil, thyme oil, carvacrol and thymol showed good in vitro bactericidal and fungicidal activity against 100 isolates from dogs with otitis externa, including some highly drug-resistant isolates. These essential oils and their main phenolic constituents have the potential to be further investigated in vivo for the treatment of canine otitis externa.