Il segreto dell’efficacia di Varicorin è la sua formula avanzata, che grazie ad un effetto sinergico influisce su molti aspetti della salute dei vasi sanguigni. Gli ingredienti sono stati selezionati in modo tale da combattere i problemi più comuni che colpiscono persone con disturbi della circolazione o persone che soffrono di gambe pesanti e gonfiore.
- Combatte efficacemente le vene varicose.
- Riduce la sensazione di pesantezza della gambe.
- Riduce il gonfiore e migliora la circolazione.
- Aiuta a eliminare l’acqua in eccesso.
- Migliora la salute delle pareti dei vasi sanguigni.
Gli studi clinici indicano chiaramente che gli ingredienti contenuti nel supplemento dietetico Varicorin aiutano l’aspetto delle gambe e la salute dei vasi sanguigni e fungono da ausiliari nella terapia: delle vene varicose, dell’edema delle gambe, dei capillari, delle emorroidi, della sensazione di pesantezza delle gambe.
Varicorin – Ingredienti
- Venocin® (Horse Chestnut Seed Extract / 20% Aescin)
- Horse Chestnut (Aesculus Hippocastanum)Species: Aesculus Hippocastanum,
Family: Sapindaceae,
European Medicines Agency: EMA: Hippocastani Semen,
European Medicines Agency: EMA: Hippocastani Cortex,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH393870,
References:
Varicose Veins: MACKAY, Douglas Hemorrhoids and varicose veins: a review of treatment options. Alternative medicine review, 2001, 6.2: 126-126. PMID:11302778, LANDER, E. Aesculus and Hamamelis in therapy of venous circulatory disorders. Medizinische Klinik, 1953, 48.2: 48. PMID:13119242.
- Aescin (C55H86O24)
Aescin: Aescin, Escin, Escin Ib, EscinI B, Escine Ib, beta-Escin,
PubChem CID: 6476031,
Chemical Abstracts Service: CAS: 26339-90-2,
ChemIDplus: 26339-90-2,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS38EA50,
References:
Varicose Veins: SCHRADER, E.; et al. Vergleichende Untersuchung zur Bioverfügbarkeit von β-Aescin nach oraler Einmalverabreichung zweier Rosskastaniensamenextrakt enthaltender, galenisch unterschiedlicher Darreichungsformen. Pharmazie, 1995, 50.9: 623-627., ANNONI, F.; MAURI, A.; MARINCOLA, F.; RESELE, L. F. Venotonic activity of escin on the human saphenous vein. Arzneimittel-Forschung, 1979, 29.4: 672-675. PMID:582766. - Aescin (C55H86O24)
- Horse Chestnut (Aesculus Hippocastanum)Species: Aesculus Hippocastanum,
- Centellin® (Asiatic Pennywort (Gotu Kola) Leaf Extract / 8% Triterpenes)
- Gotu Kola (Centella Asiatica)Species: Centella Asiatica,
Family: Apiaceae Mackinlayaceae,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH4FA6A0,
References:
Varicose Veins: ARPAIA, M. R.; FERRONE, R.; AMITRANO, M.; NAPPO, C.; LEONARDO, G.; DEL GUERCIO, R. Effects of Centella asiatica extract on mucopolysaccharide metabolism in subjects with varicose veins. International journal of clinical pharmacology research, 1990, 10.4: 229-233. PMID:2150405, INCANDELA, L.; BELCARO, G.; NICOLAIDES, A. N.; CESARONE, M. R.; DE SANCTIS, M. T.; CORSI, M.; BAVERA, P.; IPPOLITO, E.; GRIFFIN, M.; GEROULAKOS, G.; SABETAI, M.; RAMASWAMI, G.; VELLER, M. Modification of the Echogenicity of Femoral Plaques after Treatment with Total Triterpenic Fraction of Centella asiatica: A Prospective, Randomized, Placebo-Controlled Trial. Angiology, 2001, 52.2_suppl: S69-S73. PMID:11666127,
Cardiovascular Support: RAZALI, Nur Nadia Mohd; NG, Chin Theng; FONG, Lai Yen Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review. Planta medica, 2019, 85.16: 1203-1215. PMID:31539918.
- Triterpenes (C30H48)
Triterpenes: Triterpenes, Triterpene, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS391160.
- Madecassol (C48H78O19)
Madecassol: Madecassol, Asiaticoside, Centelase, Blastostimulina,
PubChem CID: 11954171,
Chemical Abstracts Service: CAS: 16830-15-2,
ChemIDplus: 16830-15-2,
FDA Substance Registration System – Unique Ingredient Identifier: UNII: PKO39VY215,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISEDBB60.
- Brahmoside
Brahmoside: Brahmoside, Brahminoside, PubChem CID: 395762, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED9450.
- Asiatic Acid (C30H48O5)
Asiatic Acid: Asiatic Acid, Asiantic Acid, Dammarolic Acid,
PubChem CID: 119034,
Chemical Abstracts Service: CAS: 464-92-6,
ChemIDplus: 464-92-6,
FDA Substance Registration System – Unique Ingredient Identifier: UNII: 9PA5A687X5,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED6D40.
- Madecassic Acid (C30H48O6)
Madecassic Acid: Madecassic Acid, Brahmic Acid, 6Beta-Hydroxyasiatic Acid,
PubChem CID: 73412,
Chemical Abstracts Service: CAS: 18449-41-7,
ChemIDplus: 18449-41-7,
FDA Substance Registration System – Unique Ingredient Identifier: UNII: M7O1N24J82,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED4630. - Brahmoside
- Madecassol (C48H78O19)
- Gotu Kola (Centella Asiatica)Species: Centella Asiatica,
- Bitter Orange Peel Extract (90% Hesperidin)
- Estratto di arancia amara (Citrus Aurantium)Species: Citrus Aurantium,
Family: Rutaceae,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2932E0,
References:
Varicose Veins: ION, Rodica-Mariana; et al. FLAVONOIDS, POLIFENOLS CONTENT AND ANTIOXIDANT ACTIVITY OF CITRUS FRUITS EXTRACTS. Researchgate, 2015..
- Esperidina (C28H34O15)
Esperidina: Hesperidin, Hesperidine, Cirantin, Hesperidoside, Hesper Bitabs, Hesperetin-Rutinosid,
PubChem CID: 10621,
Chemical Abstracts Service: CAS: 520-26-3,
ChemIDplus: 520-26-3,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2D78A0,
References:
Varicose Veins: JAWIEN, Arkadiusz.; BOUSKELA, E.; ALLAERT, F. A.; NICOLAïDES, A. N. The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of chronic venous disease. International angiology: a journal of the International Union of Angiology, 2017, 36.1: 31-41. PMID:28124877, ALLAERT, Francois-Andre Combination of Ruscus aculeatus extract, hesperidin methyl chalcone and ascorbic acid: a comprehensive review of their pharmacological and clinical effects and of the pathophysiology of chronic venous disease. International angiology: a journal of the International Union of Angiology, 2016, 35.2: 111-116. PMID:26928296.
- Estratto di arancia amara (Citrus Aurantium)Species: Citrus Aurantium,
- Butcher’s Broom Root Extract (Ruscus Aculeatus)Species: Ruscus Aculeatus,
Family: Asparagaceae,
European Medicines Agency: EMA: Rusci Aculeati Rhizoma,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH3763B0,
References:
Varicose Veins: CAPPELLI, R.; NICORA, M.; DI PERRI, T. Use of extract of Ruscus aculeatus in venous disease in the lower limbs. Drugs under experimental and clinical research, 1988, 14.4: 277-283. PMID:3048951, JAWIEN, Arkadiusz.; BOUSKELA, E.; ALLAERT, F. A.; NICOLAïDES, A. N. The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of chronic venous disease. International angiology: a journal of the International Union of Angiology, 2017, 36.1: 31-41. PMID:28124877.
- Buckwheat Seed Extract (70% Vitamin C)
- Buckwheat (Fagopyrum Esculentum)Species: Fagopyrum Esculentum,
Family: Polygonaceae,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH378AC0,
References:
Varicose Veins: IHME, N.; KIESEWETTER, H.; JUNG, F.; HOFFMANN, K. H.; BIRK, A.; MüLLER, A.; GRüTZNER, K. I. Leg oedema protection from a buckwheat herb tea in patients with chronic venous insufficiency: a single-centre, randomised, double-blind, placebo-controlled clinical trial. European Journal of Clinical Pharmacology, 1996, 50.6: 443-447. PMID:8858269.
- Vitamina C (C6H8O6)
Vitamin C deficiency is associated with a higher risk of mortality from CVD and that vitamin C may slightly improve endothelial function and lipid profiles in some groups, especially those with low plasma vitamin C levels.
Vitamina C: Ascorbic Acid, L-Ascorbic Acid, L(+)-Ascorbic Acid, Vitamin C,
PubChem CID: 54670067,
Chemical Abstracts Service: CAS: 50-81-7,
ChemIDplus: 50-81-7,
WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11GA01,
FDA Substance Registration System – Unique Ingredient Identifier: UNII: PQ6CK8PD0R,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2D5190,
References:
Cardiovascular Support: ELLULU, Mohammed S. Obesity, Cardiovascular Disease, and Role of Vitamin C on Inflammation: A Review of Facts and Underlying Mechanisms. Inflammopharmacology, 2017, 25.3: 313-328. PMID:28168552, MOSER, Melissa A.; CHUN, Ock K. Vitamin C and Heart Health: A Review Based on Findings From Epidemiologic Studies. International journal of molecular sciences, 2016, 17.8: 1328. PMID:27529239,
Varicose Veins: ALLAERT, Francois-Andre Combination of Ruscus aculeatus extract, hesperidin methyl chalcone and ascorbic acid: a comprehensive review of their pharmacological and clinical effects and of the pathophysiology of chronic venous disease. International angiology: a journal of the International Union of Angiology, 2016, 35.2: 111-116. PMID:26928296.
- Common Grape Vine Fruit Extract (2% Resveratrol)
- Common Grape Vine (Vitis Vinifera)Species: Vitis Vinifera,
Family: Vitaceae,
European Medicines Agency: EMA: Vitis Viniferae Folium,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2D9FB0,
References:
Varicose Veins: DRAIJER, Richard; DE GRAAF, Y.; SLETTENAAR, M.; DE GROOT, E.; WRIGHT, C. I. Consumption of a polyphenol-rich grape-wine extract lowers ambulatory blood pressure in mildly hypertensive subjects. Nutrients, 2015, 7.5: 3138-3153. PMID:25942487, LI, Shao-Hua; ZHAO, P.; TIAN, H. B.; CHEN, L. H.; CUI, L. Q. Effect of grape polyphenols on blood pressure: a meta-analysis of randomized controlled trials. PLoS One, 2015, 10.9: e0137665. PMID:26375022,
Cardiovascular Support: KIM, Jong-Kyung; et al. Grape Seed Extract Supplementation Attenuates the Blood Pressure Response to Exercise in Prehypertensive Men. Journal of medicinal food, 2018, 21.5: 445-453. PMID:29683391, FERINGA, Harm H. H.; et al. The Effect of Grape Seed Extract on Cardiovascular Risk Markers: A Meta-Analysis of Randomized Controlled Trials. Journal of the American Dietetic Association, 2011, 111.8: 1173-1181. PMID:21802563.
- Resveratrolo (C14H12O3)
Recent experimental studies have found that resveratrol offers a variety of benefits that include both anticarcinogenic and anti-inflammatory effects in addition to the ability to reverse obesity, attenuate hyperglycemia and hyperinsulinemia, protect heart and endothelial function, and increase the life span.
Resveratrolo: Resveratrol, Trans-Resveratrol, Resvida,
PubChem CID: 445154,
Chemical Abstracts Service: CAS: 501-36-0,
ChemIDplus: 501-36-0,
FDA Substance Registration System – Unique Ingredient Identifier: UNII: Q369O8926L,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS37B1D0,
References:
Varicose Veins: LI, Huige; XIA, N.; HASSELWANDER, S.; DAIBER, A. Resveratrol and Vascular Function. International journal of molecular sciences, 2019, 20.9: 2155. PMID:31052341,
Cardiovascular Support: CHO, Sanghyun; et al. Cardiovascular Protective Effects and Clinical Applications of Resveratrol. Journal of medicinal food, 2017, 20.4: 323-334. PMID:28346848, WICIńSKI, Michał Beneficial Effects of Resveratrol Administration-Focus on Potential Biochemical Mechanisms in Cardiovascular Conditions. Nutrients, 2018, 10.11: 1813. PMID:30469326. - Resveratrolo (C14H12O3)
- American Witch Hazel Root Extract (Hamamelis Virginiana)Species: Hamamelis Virginiana,
Family: Hamamelidaceae,
European Medicines Agency: EMA: Hamamelidis Folium,
European Medicines Agency: EMA: Hamamelidis Folium Et Cortex Aut Ramunculus Destillatum,
European Medicines Agency: EMA: Hamamelidis Cortex,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2DC6C0,
References:
Varicose Veins: LANDER, E. Aesculus and Hamamelis in therapy of venous circulatory disorders. Medizinische Klinik, 1953, 48.2: 48. PMID:13119242.
- Nettle Leaf Extract
- Ortica (Urtica Dioica)Species: Urtica Dioica,
Family: Urticaceae,
European Medicines Agency: EMA: Urticae Radix,
European Medicines Agency: EMA: Urticae Folium,
European Medicines Agency: EMA: Urticae Herba,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH27D350.
- BioPerine® (Black Pepper Fruit Extract / 95% Piperine)
- Black Pepper (Piper Nigrum)Species: Piper Nigrum,
Family: Piperaceae,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2CB550,
References:
Varicose Veins: NEWERLI-GUZ, Joanna; ŚMIECHOWSKA, Maria Assessment of the contents of piperine in black pepper berries Piper nigrum L. Bromatologia i Chemia Toksykologiczna, 2009, XLII: 827–830..
- Piperine (C17H19NO3)
Piperine: Piperine, Bioperine, Piperin, 1-Piperoylpiperidine, Piperoylpiperidine, 1-Piperylpiperidine,
PubChem CID: 638024,
Chemical Abstracts Service: CAS: 94-62-2,
ChemIDplus: 94-62-2,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS395F80,
References:
Varicose Veins: TAQVI, Syed Intasar Husain; SHAH, Abdul Jabbar; GILANI, Anwarul Hassan Blood pressure lowering and vasomodulator effects of piperine. Journal of cardiovascular pharmacology, 2008, 52.5: 452-458. PMID:19033825.
- Buckwheat Seed Extract (70% Vitamin C)
Recommended intake of this supplement: 2 capsule, daily (adults).
Additional information
Manufacturer: | NuviaLab |
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Integratori alimentari simili a Varicorin
The Varicorin dietary supplement is available in San Marino and many others countries around the world. In San Marino this supplement contains: Aescin, Asiatic Acid, BioPerine®, Bitter Orange, Black Pepper, Brahmoside, Buckwheat, Butcher’s Broom, Centellin®, Common Grape Vine, Gotu Kola, Hesperidin, Horse Chestnut, Madecassic Acid, Madecassol, Nettle, Piperine, Resveratrol, Terpenes, Triterpenes, Venocin®, Vitamin C and Witch Hazel in its composition.
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