The properties of Aescin
Aescin or escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum (the horse chestnut). Aescin is the main active compound in horse chestnut, and is responsible for most of its medicinal properties.
Evidence suggests that aescin is a safe and effective treatment for short-term treatment of chronic venous insufficiency.
Aescin has been shown to eliminate oedema and reduce exudation. It antagonizes the effect of bradykinin, although it is not a direct bradykinin antagonist.