Nonacne

This description has been derived from the manufacturer’s / distributor’s website.

O Nonacne é um suplemento completamente natural criado exclusivamente de ingredientes à base de plantas. Combate efetivamente qualquer tipo de acne, independentemente das causas da sua aparição. Graças ao Nonacne, finalmente recuperará uma pele bonita e saudável!

Inibição do excesso de secreção de sebo por glândulas sebáceas, desobstrução dos poros e efeito anti-inflamatório são as principais tarefas que pertencem ao Nonacne. Graças a esses tratamentos, a pele recupera a sua saúde e não precisamos de preocupar-nos com as borbulhas vermelhas no rosto! Além disso, o Nonacne ajuda a prevenir a aparição de novas alterações faciais, como pápulas, pústulas, cravos e cistos purulentos, que resultam da inflamação.

A aparência da acne pode também ser causada pelos distúrbios hormonais e por estas, no caso das alterações cutâneas, mais frequentemente são responsáveis os andrógenos. O Nonacne poderá lidar com este problema graças à sua estrutura e os seus componentes. O Nonacne funciona para qualquer tipo de acne, independentemente da sua fonte! Na luta com o Nonacne a acne não tem hipótese!

Os ingredientes do produto foram selecionados de tal forma que eles trabalham juntos para resolver problemas complexos de acne de forma complexa. Todos têm que cumprir a sua tarefa específica e, juntos, podem neutralizar o problema das alterações inflamatórias da pele de forma permanente e efetiva! Esta composição única inclui: trevo-vermelho, extrato de folha de urtiga, salsaparrilha, extrato de semente de uva, zinco, licopeno, cobre e vitaminas: C, A, E, B5 e B6.

Nonacne – Ingredientes

Red Clover Extract (Trifolium Pratense) [8% Isoflavones] [30:1]
- Trevo-vermelho (Trifolium Pratense)
  RCE (Red Clover Extract) supplementation exerts a subject improvement of scalp hair and skin status as well as libido, mood, sleep, and tiredness. Species: Trifolium Pratense,
  Family: Fabaceae,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2E14E0,
  References:
  Beauty: LIPOVAC, Markus; et al. Effect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal Women. Obstetrics and gynecology international, 2011, 2011: . PMID:22135679.
Sarsparilla Extract (Smilax Officinalis) [4:1]
- Sarsparilla (Smilax Officinalis)Species: Smilax Officinalis,
  Family: Smilacaceae,
  Domain: Plantae,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2E3BF0.
Grape Seed Extract (Vitis Vinifera) [95% OPC – Oligomeric Proanthocyandins] [120:1]
- Grape Seed (Vitis Vinifera)Species: Vitis Vinifera,
  Family: Vitaceae,
  European Medicines Agency: EMA: Vitis Viniferae Folium,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2E6300,
  References:
  Acne: NELSON, Kate; LYLES, J. T.; LI, T.; SAITTA, A.; ADDIE-NOYE, E.; TYLER, P.; QUAVE, C. L. Anti-acne activity of Italian medicinal plants used for skin infection. Frontiers in pharmacology, 2016, 7: 425. PMID:27891094, AL-MOUSAWI, Alia Hussein; et al. Effect of Black Grape Seed Extract (Vitis Vinifera) on Biofilm Formation of Methicillin-Resistant Staphylococcus Aureus and Staphylococcus Haemolyticus. Current Microbiology, 2020, 77.2: 238-245. PMID:31807847,
  Beauty: DI FRANCESCO, Serena; et al. Red Grape (Vitis Vinifera L.) Flavonoids Down-Regulate Collagen Type III Expression After UV-A in Primary Human Dermal Blood Endothelial Cells. Experimental dermatology, 2018, 27.9: 973-980. PMID:29742305.
Nettle Leaf Extract (Uritica Dioica) [20:1]
- Nettle Leaf (Urtica Dioica)
  Extrato de folha de urtiga reduz a secreção sebácea, apresenta ação anti-inflamatória, melhora o metabolismo, desintoxica. Species: Urtica Dioica,
  Family: Urticaceae,
  European Medicines Agency: EMA: Urticae Radix,
  European Medicines Agency: EMA: Urticae Folium,
  European Medicines Agency: EMA: Urticae Herba,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH27D350,
  References:
  Acne: KıLıç, S.; OKULLU, S. Ö.; KURT, Ö.; SEVINç, H.; DüNDAR, C.; ALTıNORDU, F.; TüRKOğLU, M. Efficacy of two plant extracts against acne vulgaris: Initial results of microbiological tests and cell culture studies. Journal of cosmetic dermatology, 2018. PMID:30414245.
Tomato Extract (Tomato Powder – Lycopersicon Esculentum) [10% Lycopene]
- Tomato (Lycopersicon Esculentum)Species: Lycopersicon Esculentum,
  Family: Solanaceae,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH373CA0.
  - Licopeno (C₄₀H₅₆)
    Licopeno: Lycopene, Trans-Lycopene, Lycopene 7, Lycored,
    PubChem CID: 446925,
    Chemical Abstracts Service: CAS: 502-65-8,
    ChemIDplus: 502-65-8,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2E8A10,
    References:
    Acne: MATSUOKA, Lois Y.; WORTSMAN, J.; TANG, G. W.; RUSSELL, R. M.; PARKER, L.; GELFAND, R.; MEHTA, R. G. Are endogenous retinoids involved in the pathogenesis of acne?. Archives of dermatology, 1991, 127.7: 1072-1073. PMID:1829604.
Vitamin A Preparation (Retinol Acetate & Maltodextrin & Dextrin & Modifield Strach & Antioxidant & D-Alpha Tocopherol)
- Vitamin A (Retinol Acetate) (C₂₂H₃₂O₂)
  Vitamin A (Retinol Acetate): Retinyl Acetate, Vitamin A Acetate, Retinol Acetate, Crystalets, Vitamin A1 Acetate, Vitamin A Alcohol Acetate, Vitamin A ester, Trans-Retinol Acetate,
  PubChem CID: 638034,
  Chemical Abstracts Service: CAS: 127-47-9,
  ChemIDplus: 127-47-9,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: 3LE3D9D6OY,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2AB980-3.
- Maltodextrin (C_6nH_(10n+2)O_(5n+1))
  Maltodextrin: Maltodextrin, Maltodextrin (NF), Maltrin (TN),
  PubChem CID: 7849388,
  Chemical Abstracts Service: CAS: 9050-36-6,
  ChemIDplus: 9050-36-6,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: 7CVR7L4A2D,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS9429B0.
- Dextrin (C₁₈H₃₂O₁₆)
  Dextrin: Dextrin, Dextrins, Fortodex, Dextrid, Nutriose, Dextrine, Deprexil, Fibersol-2,
  PubChem CID: 62698,
  Chemical Abstracts Service: CAS: 9004-53-9,
  ChemIDplus: 9004-53-9,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: 2NX48Z0A9G,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISDB1DC0.
Vitamin C As Ascorbic Acid
- Vitamina C (C₆H₈O₆)
  Vitamina C: Ascorbic Acid, L-Ascorbic Acid, L(+)-Ascorbic Acid, Vitamin C,
  PubChem CID: 54670067,
  Chemical Abstracts Service: CAS: 50-81-7,
  ChemIDplus: 50-81-7,
  WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11GA01,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: PQ6CK8PD0R,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2D5190,
  References:
  Acne: MORRIS, George E. Use of vitamin C in acne vulgaris. AMA archives of dermatology and syphilology, 1954, 70.3: 363-364. PMID:13188475.
Cooper As Copper Gluconate
- Cobre (gluconato cúprico) (C₁₂H₂₂CuO₁₄)
  Cobre (gluconato cúprico): Copper Gluconate, Cupric Gluconate, Copper Di-D-Gluconate, Gluconates, Cupric Gluconate Monohydrate,
  PubChem CID: 10692,
  Chemical Abstracts Service: CAS: 527-09-3,
  ChemIDplus: 527-09-3,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2A9270-1,
  References:
  Acne: FRANCK, P. Acne conglobata rapidly cured with intravenous copper sulfate. Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1951, 58.1: 75-76. PMID:14839451, PARSONS, H. H. The Use of Copper in Acne. California and western medicine, 1933, 38.1: 42. PMID:18742384.
Zinc As Zinc Citrate
- Zinco (citrato de zinco) (C₁₂H₁₀O₁₄Zn₃)
  Zinco (citrato de zinco): Zinc Citrate, Trizinc Dicitrate, Citric Acid,
  PubChem CID: 11023,
  Chemical Abstracts Service: CAS: 546-46-3,
  ChemIDplus: 546-46-3,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: K72I3DEX9B,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS26E8F0-1.
DL-Alpha Tocopheryl Acetate (Vitamin E)
- Vitamina E (α-tocoferol) (C₂₉H₅₀O₂)
  Vitamin E has antioxidant properties.
  Vitamina E (α-tocoferol): Vitamin E, Alpha-Tocopherol, Α-Tocopherol, D-Alpha-Tocopherol, DL-Alpha Tocopheryl Acetate, DL-Alpha-Tocopheryl Acetate,
  PubChem CID: 14985,
  Chemical Abstracts Service: CAS: 59-02-9,
  ChemIDplus: 59-02-9,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2A4450,
  References:
  Acne: ACHARYA, S. R. Vitamin E (tocoferol acetate) in the treatment of adolescent acne. The Journal of the Association of Physicians of India, 1990, 38.2: 189-190. PMID:2143182, DE LUCA, C.; DEEVA, I.; MIKHAL’CHIK, E.; KORKINA, L. Beneficial effects of pro-/antioxidant-based nutraceuticals in the skin rejuvenation techniques. Cellular and molecular biology (Noisy-le-Grand, France), 2007, 53.1: 94-101. PMID:17519117.
Vitamin B5 && B6
- Vitamina B
  Vitamina B: Vitamin B, B Vitamins, .
  - Vitamina B5 (ácido pantotênico) (C₉H₁₇NO₅)
    Vitamina B5 (ácido pantotênico): D-Pantothenic Acid, Vitamin B5, Pantothenic Acid, Pantothenate,
    PubChem CID: 6613,
    Chemical Abstracts Service: CAS: 79-83-4,
    ChemIDplus: 79-83-4,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA31,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 19F5HK2737,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS26C1E0,
    References:
    Acne: LEUNG, L. H. Pantothenic acid deficiency as the pathogenesis of acne vulgaris. Medical hypotheses, 1995, 44.6: 490-492. PMID:7476595, YANG, Michael; MOCLAIR, B.; HATCHER, V.; KAMINETSKY, J.; MEKAS, M.; CHAPAS, A.; CAPODICE, J. A randomized, double-blind, placebo-controlled study of a novel pantothenic acid-based dietary supplement in subjects with mild to moderate facial acne. Dermatology and therapy, 2014, 4.1: 93-101. PMID:24831048.
  - Vitamina B6 (piridoxina) (C₈H₁₁NO₃)
    Vitamin B6 regulates hormonal activity.
    Vitamina B6 (piridoxina): Pyridoxine, Gravidox, Pyridoxol, Vitamin B6,
    PubChem CID: 1054,
    Chemical Abstracts Service: CAS: 65-23-6,
    ChemIDplus: 65-23-6,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA02,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: KV2JZ1BI6Z,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS264CB0,
    References:
    Acne: LINCKE-PLEWIG, H. Vitamins B6 and B12 in acne?. Deutsche medizinische Wochenschrift (1946), 1978, 103.3: 1292. PMID:150326.

Recommended intake of this supplement: 2 capsule, daily (adults).

Additional information

Manufacturer:	NuviaLab

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The Nonacne dietary supplement is available in Sao Tome and Principe and many others countries around the world. In Sao Tome and Principe this supplement contains: Copper, Dextrin, Grape Seed, Lycopene, Maltodextrin, Nettle, Red Clover, Sarsparilla, Tomato, Vitamin A, Vitamin B5, Vitamin B6, Vitamin C, Vitamin E and Zinc in its composition.

Detailed descriptions of the ingredients included in the Nonacne dietary supplement:

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