What are the properties of Lycopene in supplements?

Lycopene - References & External links

Lycopene

TBS Ingredient ID (TBSI ID):	IS2E8A10
Name
Lycopene Synonyms: Trans-Lycopene, Lycopene 7, Lycored
Chemical Formula:
C40H56
Molecular Formula:
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	446925
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	OAIJSZIZWZSQBC-GYZMGTAESA-N
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	502-65-8
NIST: The National Institute of Standards and Technology (NIST)	502-65-8
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	502-65-8
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	207-949-1
ChEBI: Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.	15948

The references to scientific articles about Lycopene are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• The general properties of Lycopene:
  • GRETHER-BECK, S.; et al. Molecular evidence that oral supplementation with lycopene or lutein protects human skin against ultraviolet radiation: results from a double-blinded, placebo-controlled, crossover study. British Journal of Dermatology, 2017, 176.5: 1231-1240. PMID:27662341
    CONCLUSIONS: Assuming the role of these genes as indicators of oxidative stress, photodermatoses and photoageing, these results might indicate that TNC and lutein could protect against solar radiation-induced health damage.
  • GRABOWSKA, Małgorzata; et al. Let food be your medicine: nutraceutical properties of lycopene. Food & function, 2019. PMID:31120074
  • WALISZEWSKI, Krzysztof N.; BLASCO, Gabriela. Nutraceutical properties of lycopene. Salud publica de Mexico, 2010, 52.3: 254-265. PMID:20485889
  • MCCLAIN, R. Michael; BAUSCH, Jochen. Summary of safety studies conducted with synthetic lycopene. Regulatory Toxicology and Pharmacology, 2003, 37.2: 274-285. PMID:12726756
• Influence of Lycopene on the Immune Response:
  Researchers suggested that lycopene, in addition to its ability to attack free radicals, may also reduce inflammation and cholesterol, improve immune function, and prevent blood from clotting.
  • CHEW, Boon P.; PARK, Jean Soon. Carotenoid Action on the Immune Response. The Journal of nutrition, 2004, 134.1: 257S-261S. PMID:14704330
  • PALOZZA, Paola; et al. Tomato Lycopene and Inflammatory Cascade: Basic Interactions and Clinical Implications. Current medicinal chemistry, 2010, 17.23: 2547-2563. PMID:20491642
• The properties of Lycopene improving Heart Health:
  • CHENG, Ho Ming; et al. Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis. Atherosclerosis, 2017, 257: 100-108. PMID:28129549
    CONCLUSIONS: The available evidence on the effects of tomato products and lycopene supplementation on CV risk factors supports the view that increasing the intake of these has positive effects on blood lipids, blood pressure and endothelial function. These results support the development of promising individualised nutritional strategies involving tomatoes to tackle CVD.
  • BURTON-FREEMAN, Britt M.; SESSO, Howard D. Whole food versus supplement: comparing the clinical evidence of tomato intake and lycopene supplementation on cardiovascular risk factors. Advances in Nutrition, 2014, 5.5: 457-485. PMID:25469376
  • MCENENY, Jane; et al. Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals. The Journal of nutritional biochemistry, 2013, 24.1: 163-168. PMID:22819555
  • GAJENDRAGADKAR, Parag R.; et al. Effects of oral lycopene supplementation on vascular function in patients with cardiovascular disease and healthy volunteers: a randomised controlled trial. PloS one, 2014, 9.6: e99070. PMID:24911964
    CONCLUSIONS: Lycopene supplementation improves endothelial function in CVD patients on optimal secondary prevention, but not in HVs. TRIAL REGISTRATION: ClinicalTrials.gov NCT01100385.
• The properties of Lycopene preventing Acne:
  • MATSUOKA, Lois Y.; WORTSMAN, J.; TANG, G. W.; RUSSELL, R. M.; PARKER, L.; GELFAND, R.; MEHTA, R. G. Are endogenous retinoids involved in the pathogenesis of acne?. Archives of dermatology, 1991, 127.7: 1072-1073. PMID:1829604
• The properties of Lycopene for Weight Loss:
  • ABDALI, Daniyal; SAMSON, Sue E.; GROVER, Ashok Kumar. How Effective Are Antioxidant Supplements in Obesity and Diabetes?. Medical Principles and Practice, 2015, 24.3: 201-215. PMID:25791371
• The properties of Lycopene improving Eye Health:
  • JOHRA, Fatima Tuj; et al. A Mechanistic Review of β-Carotene, Lutein, and Zeaxanthin in Eye Health and Disease. Antioxidants, 2020, 9.11: 1046. PMID:33114699