Wrinkle Free Skin Formula

Wrinkle Free Skin Formula – Ingredients

• Vitamin A (as Beta Carotene)
  • Vitamin A (Beta-Carotene) (C₄₀H₅₆)
    Vitamin A (Beta-Carotene): Beta-Carotene, Beta Carotene, Provitamin A, Betacarotene, Solatene, Carotaben, Provatene, Serlabo, PubChem CID: 5280489, Chemical Abstracts Service: CAS: 7235-40-7, ChemIDplus: 7235-40-7, WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11CA02, FDA Substance Registration System – Unique Ingredient Identifier: UNII: 01YAE03M7J, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2AB980-1.
    
• Vitamin C (ascorbic Acid)
  • Vitamin C (Ascorbic Acid) (C₆H₈O₆)
    Vitamin C (Ascorbic Acid): Ascorbic Acid, L-Ascorbic Acid, L(+)-Ascorbic Acid, Vitamin C,
    PubChem CID: 54670067,
    Chemical Abstracts Service: CAS: 50-81-7,
    ChemIDplus: 50-81-7,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11GA01,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: PQ6CK8PD0R,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2D5190,
    References:
    Wrinkle: ABDULLAH, M.; ATTIA, F. N. Vitamin C (Ascorbic Acid). Treasure Island (FL): StatPearls Publishing, 2019. PMID:29763052, MAIONE-SILVA, L.; DE CASTRO, E. G.; NASCIMENTO, T. L.; CINTRA, B. A. S.; MOREIRA, L. C.; VALADARES, M. C.; LIMA, E. M. Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts. Scientific reports, 2019, 9.1: 522. PMID:30679479.
    
• Vitamin E (d-Alpha Tocopherol)
  • Vitamin E (α-Tocopherol) (C₂₉H₅₀O₂)
    Vitamin E (α-Tocopherol): Vitamin E, Alpha-Tocopherol, Α-Tocopherol, D-Alpha-Tocopherol, DL-Alpha Tocopheryl Acetate, DL-Alpha-Tocopheryl Acetate,
    PubChem CID: 14985,
    Chemical Abstracts Service: CAS: 59-02-9,
    ChemIDplus: 59-02-9,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2A4450,
    References:
    Wrinkle: MORREALE, Massimiliano; LIVREA, Maria A Synergistic effect of glycolic acid on the antioxidant activity of α‐tocopherol and melatonin in lipid bilayers and in human skin homogenates. IUBMB Life, 1997, 42.6: 1093-1102. PMID:9305527, DE LUCA, C.; DEEVA, I.; MIKHAL’CHIK, E.; KORKINA, L. Beneficial effects of pro-/antioxidant-based nutraceuticals in the skin rejuvenation techniques. Cellular and molecular biology (Noisy-le-Grand, France), 2007, 53.1: 94-101. PMID:17519117.
    
• Niacinamide (C₆H₆N₂O)
  Niacinamide: Nicotinamide, Nikotinamid, Nicotylamide, 3-Pyridinecarboxamide, Nicotinic Acid Amide, Aminicotin, PubChem CID: 936, Chemical Abstracts Service: CAS: 98-92-0, ChemIDplus: 98-92-0, WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA01, FDA Substance Registration System – Unique Ingredient Identifier: UNII: 25X51I8RD4, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS30FB10-1.
  
  • Vitamin B3 (niacin/nicotinic acid) (C₆H₅NO₂ or HOOC₅H₄N or C₅H₄NCOOH)
    Vitamin B3 (niacin/nicotinic acid): Nicotinic Acid, Vitamin B3, Vitamin PP, Niacin, Pyridine-3-Carboxylic Acid, 3-Pyridinecarboxylic Acid,
    PubChem CID: 938,
    Chemical Abstracts Service: CAS: 59-67-6,
    ChemIDplus: 59-67-6,
    WHO Anatomical Therapeutic Chemical Classification System: ATC code: C04AC01,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: 25X51I8RD4,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS30FB10,
    References:
    Wrinkle: BURGESS, C. Topical vitamins. Journal of drugs in dermatology: JDD, 2008, 7.7 Suppl: s2-6. PMID:18681152, CHEN, Andrew C.; DAMIAN, D. L. Nicotinamide and the skin. Australasian Journal of Dermatology, 2014, 55.3: 169-175. PMID:24635573.
    
• Resveratrol (15-20% Polygonum Cuspidatum/Fallopia Japonica)
  • Polygonum Cuspidatum (Reynoutria Japonica)Species: Reynoutria Japonica, Family: Polygonaceae.
    
    
  • Resveratrol (C₁₄H₁₂O₃)
    Resveratrol: Resveratrol, Trans-Resveratrol, Resvida,
    PubChem CID: 445154,
    Chemical Abstracts Service: CAS: 501-36-0,
    ChemIDplus: 501-36-0,
    FDA Substance Registration System – Unique Ingredient Identifier: UNII: Q369O8926L,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS37B1D0.
    
• Alpha-Lipoic Acid (C₈H₁₄O₂S₂)
  Alpha-Lipoic Acid: Thioctic Acid, Lipoic Acid, Thioctacid, Lipothion, Biletan, Liposan, Thioctsan,
  PubChem CID: 864,
  Chemical Abstracts Service: CAS: 1077-28-7,
  ChemIDplus: 1077-28-7,
  WHO Anatomical Therapeutic Chemical Classification System: ATC code: A16AX01,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: VLL71EBS9Z,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS3ABF10.
  
• Aloe Vera Gel (200:1 Concentrate)
  • Aloe Vera (Aloe Vera)Species: Aloe Vera,
    Family: Asphodelaceae,
    European Medicines Agency: EMA: Aloes Folii Succus Siccatus,
    Domain: Plantae,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH498C20,
    References:
    Wrinkle: HEKMATPOU, Davood; et al. The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review. Iranian journal of medical sciences, 2019, 44.1: 1. PMID:30666070, XING, Wei; et al. Acemannan Accelerates Cell Proliferation and Skin Wound Healing Through AKT/mTOR Signaling Pathway. Journal of Dermatological Science, 2015, 79.2: 101-109. PMID:26049685.
    
    
• Collagen
  Collagen: Collagen, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2F2650.
  
• Green Tea (50% Extract)
  • Green Tea (Camellia Sinensis)Species: Camellia Sinensis,
    Family: Theaceae,
    European Medicines Agency: EMA: Camelliae Sinensis Non Fermentatum Folium,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2B07A0.
    
    
• Grape Seed (95% Extract)
  • Grape Seed (Vitis Vinifera)Species: Vitis Vinifera,
    Family: Vitaceae,
    European Medicines Agency: EMA: Vitis Viniferae Folium,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH2E6300,
    References:
    Beauty: DI FRANCESCO, Serena; et al. Red Grape (Vitis Vinifera L.) Flavonoids Down-Regulate Collagen Type III Expression After UV-A in Primary Human Dermal Blood Endothelial Cells. Experimental dermatology, 2018, 27.9: 973-980. PMID:29742305.
    
    
• DMAE (C₄H₁₁NO or (CH₃)₂NCH₂CH₂OH)
  DMAE: Deanol, Demanol, Dimethylethanolamine, DMEA, Dimethylaminoethanol, Dimethylaminoaethanol, Norcholine, Bimanol, Liparon, Varesal, Propamine A, Kalpur P, N-Dimethylaminoethanol, PubChem CID: 7902, Chemical Abstracts Service: CAS: 108-01-0, ChemIDplus: 108-01-0, WHO Anatomical Therapeutic Chemical Classification System: ATC code: N06BX04, FDA Substance Registration System – Unique Ingredient Identifier: UNII: 2N6K9DRA24, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS49B330.
  
• Hyaluronic Acid (C₃₃H₅₄N₂O₂₃)
  Hyaluronic Acid: Hyaluronic Acid, Etamucine, Luronit, Amvisc, Biolon, Hylan G-F 20, Hyvisc, Mucoitin, Sepracoat, Sofast, PubChem CID: 24847767, Chemical Abstracts Service: CAS: 9004-61-9, ChemIDplus: 9004-61-9, WHO Anatomical Therapeutic Chemical Classification System: ATC code: D03AX05, FDA Substance Registration System – Unique Ingredient Identifier: UNII: S270N0TRQY, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS49DA40.
  
• L-Glycine (C₂H₅NO₂)
  L-Glycine: Glycine, Glycolixir, Glycosthene, Glicoamin, Amitone, Aminoethanoic Acid, Glycinum, Corilin, Glyzin, PubChem CID: 750, Chemical Abstracts Service: CAS: 56-40-6, ChemIDplus: 56-40-6, WHO Anatomical Therapeutic Chemical Classification System: ATC code: B05CX03, FDA Substance Registration System – Unique Ingredient Identifier: UNII: TE7660XO1C, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS4A0150.
  
• L-Proline (C₅H₉NO₂)
  L-Proline: L-Proline, Proline, L-(-)-Proline, Prolina, Prolinum, PubChem CID: 145742, Chemical Abstracts Service: CAS: 147-85-3, ChemIDplus: 147-85-3, FDA Substance Registration System – Unique Ingredient Identifier: UNII: DCS9E77JPQ, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS4A2860.
  
• L-Glutathione Reduced (C₁₀H₁₇N₃O₆S)
  L-Glutathione Reduced: Glutathione, L-Glutathione, Glutathion, Isethion, Tathion, GSH, Reduced Glutathione, Glutinal, Gamma-L-Glutamylcysteinylglycine, Glutatiol, Glutatione, PubChem CID: 124886, Chemical Abstracts Service: CAS: 70-18-8, ChemIDplus: 70-18-8, WHO Anatomical Therapeutic Chemical Classification System: ATC code: V03AB32, FDA Substance Registration System – Unique Ingredient Identifier: UNII: GAN16C9B8O, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS4A4F70.
  
• Turmeric Extract (95% Curcuminoids)
  • Turmeric (Curcuma Longa)Species: Curcuma Longa,
    Family: Zingiberaceae,
    European Medicines Agency: EMA: Curcumae Longae Rhizoma,
    The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH4A7680.