What are the properties of Vitamin D3 in supplements?

The Supplements with Vitamin D3The Supplements with Vitamin D3

The properties of Vitamin D3

Cholecalciferol, also known as vitamin D3 and colecalciferol, is a type of vitamin D which is made by the skin when exposed to sunlight; it is also found in some foods and can be taken as a dietary supplement. It is used to treat and prevent vitamin D deficiency and associated diseases, including rickets. It is also used for familial hypophosphatemia, hypoparathyroidism that is causing low blood calcium, and Fanconi syndrome. It is usually taken by mouth.

Vitamin D is a fat soluble vitamin important in the regulation of calcium metabolism and bone health and deficiency of which cause rickets, a disease marked by lack of mineralization of bone. Conventional doses of vitamin D are well tolerated without appreciable adverse effects. High doses of vitamin D can be toxic, leading to a constellation of signs and symptoms but not liver injury or jaundice.

In humans, evidence exists on associations between vitamin D deficiency and impaired immune function, leading to autoimmunity in genetically predisposed people and increased risk for infections(889).

Vitamin D regulates both adaptive and innate immunity as well as inflammatory cascade on the cellular level(891).

Vitamin D is important for both cellular metabolism and immunity, as it controls calcium homeostasis and modulates the response of the innate and adaptive immune system. At sufficient UV-B exposure, humans can synthesize vitamin D₃ endogenously in their skin, but today's lifestyle often makes the molecule a true vitamin and micronutrient that needs to be taken up by diet or supplementation with pills.

The individual's molecular response to vitamin D requires personalized supplementation with vitamin D₃, in order to obtain optimized clinical benefits in the prevention of osteoporosis, sarcopenia, autoimmune diseases, and possibly different types of cancer(893).

Vitamin D and human skin. Vitamin D3 is synthesized endogenously in UV-B exposed human skin
Vitamin D and human skin. Vitamin D3 is synthesized endogenously in UV-B exposed human skin (A). During the past 10–30,000 years this essential need to synthesize vitamin D3 was an evolutionary driver for skin lightening of modern humans migrating from Africa towards Europe and Asia (B).

Cholecalciferol - Description from DrugBank

 

Cholecalciferol - Description from NCI Thesaurus

 

Cholecalciferol - Description from HMDB

 


The supplements containing Vitamin D3


Testo PrimeTesto Prime

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Testo Prime contains amoung others Vitamin D3.

Testo Prime is available in many countries around the world.

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TestoPrime is an all-natural testosterone support that can help any man take control of his youthful vitality with a flood of new and natural testosterone. Experience The Proven Body-Sculpting Benefits Of TestoPrime’s Ingredients.
TestoGenTestoGen

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TestoGen contains amoung others Vitamin D3.

TestoGen is available in many countries around the world.

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Natural Testosterone Booster Amazing Results. TestoGen contains natural ingredients to boost your testosterone easily and safely. As you get older, testosterone levels begin to fall and it becomes harder to perform at your best. Now you can do something about this safely and naturally.
Vitabase - Calcium & MagnesiumVitabase - Calcium & Magnesium

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Vitabase – Calcium & Magnesium contains amoung others Vitamin D3.

Vitabase – Calcium & Magnesium is available in many countries around the world.

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This high potency calcium product combines three different kinds of calcium, vitamin D, magnesium and boron into 1 capsule. Since different people handle calcium types in various ways, calcium citrate, calcium carbonate, and chelated calcium are all included. This calcium product provides a 2:1...
Vitabase - Enfūz (Advanced)Vitabase - Enfūz (Advanced)

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Vitabase – Enfūz (Advanced) contains amoung others Vitamin D3.

Vitabase – Enfūz (Advanced) is available in many countries around the world.

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Enfūz Advanced is a complete nutritional supplement program designed to meet your basic nutritional needs. It contains vitamins, minerals, antioxidants, fish oil, extra vitamin D, and more. Choosing which health supplements to take on a regular basis can be a very frustrating process. Often...
Vitamin D3 (Cholecalciferol), 125 mcg (5,000 IU), 100 Softgels (Solgar)Vitamin D3 (Cholecalciferol), 125 mcg (5,000 IU), 100 Softgels (Solgar)

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Vitamin D3 (Cholecalciferol), 125 mcg (5,000 IU), 100 Softgels (Solgar) contains amoung others Vitamin D3.

Vitamin D3 (Cholecalciferol), 125 mcg (5,000 IU), 100 Softgels (Solgar) is available in many countries around the world.

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Vitamin D is required to promote calcium absorption, which helps to maintain healthy bones and teeth. Vitamin D also supports a healthy immune system. The Vitamin D3 in this product is the same form produced by the body when our skin is exposed to sunlight. As we age, our bodies may produce this...
PowerCal, Advanced Calcium Formula, 1,000 mg, 180 Tablets (Zahler)PowerCal, Advanced Calcium Formula, 1,000 mg, 180 Tablets (Zahler)

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PowerCal, Advanced Calcium Formula, 1,000 mg, 180 Tablets (Zahler) contains amoung others Vitamin D3.

PowerCal, Advanced Calcium Formula, 1,000 mg, 180 Tablets (Zahler) is available in many countries around the world.

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PowerCal tablets is a supplement formulated to promote stronger bones, teeth and healthy gums. PowerCal also helps the body maintain a regular heartbeat and aids in muscle contraction and neurotransmitter release.
Vitamin D-3 Drops, 4,000 IU, 0.5 fl oz (15 ml) (Nature's Answer)Vitamin D-3 Drops, 4,000 IU, 0.5 fl oz (15 ml) (Nature's Answer)

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Vitamin D-3 Drops, 4,000 IU, 0.5 fl oz (15 ml) (Nature's Answer) contains amoung others Vitamin D3.

Vitamin D-3 Drops, 4,000 IU, 0.5 fl oz (15 ml) (Nature's Answer) is available in many countries around the world.

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Vitamin D is called the 'Sunshine Vitamin' because it is produced naturally by the body after exposure to 20 min - 1/2 hour of sunlight. Many people develop deficiencies due to lack of sun exposure, living in cold climates, and other reasons. Vitamin D is most well known for its contribution to...
Sentry, Multivitamin & Multimineral Supplement, 300 Tablets (21st Century)Sentry, Multivitamin & Multimineral Supplement, 300 Tablets (21st Century)

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Sentry, Multivitamin & Multimineral Supplement, 300 Tablets (21st Century) contains amoung others Vitamin D3.

Sentry, Multivitamin & Multimineral Supplement, 300 Tablets (21st Century) is available in many countries around the world.

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21st Century - Multivitamin & Multimineral Supplement.
PowerCal, Advanced Calcium Formula, 900 mg, 360 Capsules (Zahler)PowerCal, Advanced Calcium Formula, 900 mg, 360 Capsules (Zahler)

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PowerCal, Advanced Calcium Formula, 900 mg, 360 Capsules (Zahler) contains amoung others Vitamin D3.

PowerCal, Advanced Calcium Formula, 900 mg, 360 Capsules (Zahler) is available in many countries around the world.

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Promotes Healthy Bones, Teeth, and Gums
Vitamin D3 (Cholecalciferol), 25 mcg (1,000 IU), 250 Softgels (Solgar)Vitamin D3 (Cholecalciferol), 25 mcg (1,000 IU), 250 Softgels (Solgar)

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Vitamin D3 (Cholecalciferol), 25 mcg (1,000 IU), 250 Softgels (Solgar) contains amoung others Vitamin D3.

Vitamin D3 (Cholecalciferol), 25 mcg (1,000 IU), 250 Softgels (Solgar) is available in many countries around the world.

If you are not in The United Kingdom (GB)
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Vitamin D is a fat-soluble vitamin that is required to promote calcium absorption, which helps to maintain healthy bones and teeth. Vitamin D also supports a healthy immune system and neuromuscular function. The Vitamin D3 in this product is the same form produced by the body when our skin is...
Liquid Norwegian Cod Liver Oil, Natural Lemon-Lime Flavor, 16 fl oz (480 ml) (Nature's Answer)Liquid Norwegian Cod Liver Oil, Natural Lemon-Lime Flavor, 16 fl oz (480 ml) (Nature's Answer)

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Liquid Norwegian Cod Liver Oil, Natural Lemon-Lime Flavor, 16 fl oz (480 ml) (Nature's Answer) contains amoung others Vitamin D3.

Liquid Norwegian Cod Liver Oil, Natural Lemon-Lime Flavor, 16 fl oz (480 ml) (Nature's Answer) is available in many countries around the world.

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Nature’s Answer Liquid Cod Liver Oil is harvested from the deep, clean, cold waters of the North Atlantic. Micro-filtered using a thorough multi-step molecular distillation process to remove toxins such as mercury, lead, PBCs and dioxins, it’s the finest natural Omega 3 cod liver oil...
Vitamin D-3 High Potency, 1,000 IU, 180 Softgels (Now Foods)Vitamin D-3 High Potency, 1,000 IU, 180 Softgels (Now Foods)

English version


Vitamin D-3 High Potency, 1,000 IU, 180 Softgels (Now Foods) contains amoung others Vitamin D3.

Vitamin D-3 High Potency, 1,000 IU, 180 Softgels (Now Foods) is available in many countries around the world.

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NOW Vitamin D-3 softgels supply this key vitamin in a highly-absorbable liquid softgel form. Vitamin D is normally obtained from the diet or produced by the skin from the ultraviolet energy of the sun. However, it is not abundant in food. As more people avoid sun exposure, Vitamin D supplementation...
Ultra Omega 3-D, 600 EPA/300 DHA, 180 Softgels (Now Foods)Ultra Omega 3-D, 600 EPA/300 DHA, 180 Softgels (Now Foods)

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Ultra Omega 3-D, 600 EPA/300 DHA, 180 Softgels (Now Foods) contains amoung others Vitamin D3.

Ultra Omega 3-D, 600 EPA/300 DHA, 180 Softgels (Now Foods) is available in many countries around the world.

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Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease.
Vitamin D-3, 400 IU, 180 Softgels (Now Foods)Vitamin D-3, 400 IU, 180 Softgels (Now Foods)

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Vitamin D-3, 400 IU, 180 Softgels (Now Foods) contains amoung others Vitamin D3.

Vitamin D-3, 400 IU, 180 Softgels (Now Foods) is available in many countries around the world.

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Now Vitamin D-3 softgels supply this key vitamin in a highly-absorbable liquid softgel form. Vitamin D is normally obtained from the diet or produced by the skin from the ultraviolet energy of the sun. However, it is not abundant in food. As more people avoid sun exposure, Vitamin D supplementation...
Vitamin D3 (Cholecalciferol), 250 mcg (10,000 IU), 120 Softgels (Solgar)Vitamin D3 (Cholecalciferol), 250 mcg (10,000 IU), 120 Softgels (Solgar)

English version


Vitamin D3 (Cholecalciferol), 250 mcg (10,000 IU), 120 Softgels (Solgar) contains amoung others Vitamin D3.

Vitamin D3 (Cholecalciferol), 250 mcg (10,000 IU), 120 Softgels (Solgar) is available in many countries around the world.

If you are not in The United Kingdom (GB)
>> Select Your Country <<


 
Vitamin D is required to promote calcium absorption, which helps to maintain healthy bones and teeth. Vitamin D also supports a healthy immune system and neuromuscular function. The Vitamin D3 in this product is the same form produced by the body when our skin is exposed to sunlight. As we age, our...
Vitamin D-3 & K-2, 1,000 IU / 45 mcg, 120 Veg Capsules (Now Foods)Vitamin D-3 & K-2, 1,000 IU / 45 mcg, 120 Veg Capsules (Now Foods)

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Vitamin D-3 & K-2, 1,000 IU / 45 mcg, 120 Veg Capsules (Now Foods) contains amoung others Vitamin D3.

Vitamin D-3 & K-2, 1,000 IU / 45 mcg, 120 Veg Capsules (Now Foods) is available in many countries around the world.

If you are not in The United Kingdom (GB)
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NOW combines two nutrients extensively researched for their contribution to the health of bones, teeth and the cardiovascular system. Vitamin D3 promotes Calcium transport and absorption. Recent studies indicate that Vitamin D3 may play a role in proper insulin action and glucose metabolism and has...
Liquid Vitamin D-3, Extra Strength, 1,000 IU, 1 fl oz (30 ml) (Now Foods)Liquid Vitamin D-3, Extra Strength, 1,000 IU, 1 fl oz (30 ml) (Now Foods)

English version


Liquid Vitamin D-3, Extra Strength, 1,000 IU, 1 fl oz (30 ml) (Now Foods) contains amoung others Vitamin D3.

Liquid Vitamin D-3, Extra Strength, 1,000 IU, 1 fl oz (30 ml) (Now Foods) is available in many countries around the world.

If you are not in The United Kingdom (GB)
>> Select Your Country <<


 
Vitamin D is normally obtained from the diet or produced by the skin from the ultraviolet energy of the sun. However, it is not abundant in food. As more people avoid sun exposure, Vitamin D supplementation becomes even more necessary to ensure that your body receives an adequate supply.
Mega D-3 & MK-7, 5000 IU / 180 mcg, 60 Veg Capsules (Now Foods)Mega D-3 & MK-7, 5000 IU / 180 mcg, 60 Veg Capsules (Now Foods)

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Mega D-3 & MK-7, 5000 IU / 180 mcg, 60 Veg Capsules (Now Foods) contains amoung others Vitamin D3.

Mega D-3 & MK-7, 5000 IU / 180 mcg, 60 Veg Capsules (Now Foods) is available in many countries around the world.

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NOW Mega D-3 & MK-7 combines vitamins D-3 and K-2, two nutrients extensively researched for their roles in the health of bones, teeth and the cardiovascular system. Vitamin D-3 works with calcium to support bone health, and more recent studies indicate it's important for immune system health as...
Calcium Magnesium Zinc + D3, 90 Tablets (21st Century)Calcium Magnesium Zinc + D3, 90 Tablets (21st Century)

English version


Calcium Magnesium Zinc + D3, 90 Tablets (21st Century) contains amoung others Vitamin D3.

Calcium Magnesium Zinc + D3, 90 Tablets (21st Century) is available in many countries around the world.

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Calcium, Magnesium and Zinc, an important mineral trio plus D3, supports bones, muscles and the immune system.
Liquid Vitamin D-3, 2 fl oz (60 ml) (Now Foods)Liquid Vitamin D-3, 2 fl oz (60 ml) (Now Foods)

English version


Liquid Vitamin D-3, 2 fl oz (60 ml) (Now Foods) contains amoung others Vitamin D3.

Liquid Vitamin D-3, 2 fl oz (60 ml) (Now Foods) is available in many countries around the world.

If you are not in The United Kingdom (GB)
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Each drop contains 100 IU of Vitamin D, 4 drops provide 400 IU, 20 drops provide 2,000 IU.
Magnesium & Calcium, Reverse 2:1 Ratio with Zinc and Vitamin D-3 250 Tablets (Now Foods)Magnesium & Calcium, Reverse 2:1 Ratio with Zinc and Vitamin D-3 250 Tablets (Now Foods)

English version


Magnesium & Calcium, Reverse 2:1 Ratio with Zinc and Vitamin D-3 250 Tablets (Now Foods) contains amoung others Vitamin D3.

Magnesium & Calcium, Reverse 2:1 Ratio with Zinc and Vitamin D-3 250 Tablets (Now Foods) is available in many countries around the world.

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This reverse ratio formula is formulated to provide higher levels of Magnesium for those who desire the nerve, muscle and bone supporting effects of this essential mineral. Zinc and Vitamin D-3 are included in this product for their roles in bone metabolism.

If you know of any other quality supplement that has not been yet classified by us, please contact us and we will gladly consider adding it to our catalogue.


Vitamin D3 (cholecalciferol) - References & External links

Vitamin D3 (Cholecalciferol)

TBS Ingredient ID (TBSI ID):
Name
Vitamin D3
Synonyms:
Calciol, Colecalciferol
Chemical Formula:
C27H44O
Molecular Formula:
Cholecalciferol - Molecular Formula
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
QYSXJUFSXHHAJI-YRZJJWOYSA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
67-97-0
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
215-797-2
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.

Show: Cholecalciferol - description from DrugBank
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
HMDB:
The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.

Show: Cholecalciferol - description from HMDB
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Cholecalciferol - description from NCI Thesaurus
UNII:
FDA Substance Registration System - Unique Ingredient Identifier

The references to scientific articles about Vitamin D3 (cholecalciferol) are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.