What are the properties of Vitamin B6 in supplements?

The Supplements with Vitamin B6The Supplements with Vitamin B6

The properties of Vitamin B6

Vitamin B6 (pyridoxine C8H11NO3). Ensures proper energy metabolism. It regulates the functioning of the endocrine system and maintains internal balance.

Though all B vitamins are essential, Vitamin B6 is one of the most important. It plays a role in over 100 enzyme reactions in the body, primarily in the metabolism of important amino acids and proteins. Vitamin B6 is one of the most common deficiencies.

Vitamin B6 (pyridoxine) is closely associated with the functions of the nervous, immune and endocrine systems. It also participates in the metabolic processes of proteins, lipids and carbohydrates. Pyridoxine deficiency may result in neurological disorders including convulsions and epileptic encephalopathy and may lead to infant abnormalities(301), (1122).

Recommended Daily Allowance

Vitamin B6 – Recommended Daily Allowance: 1.3/1.3 mg (1.7/1.5 mg >50 year).

Symptoms of Deficiency

Anaemia.

Specific Risk Factors for Deficiency

Alcohol abuse, age-related malabsorption, contraceptive medications.

Dietary Sources

Good Dietary Sources of Vitamin B6:

  • meat,
  • fish,
  • eggs,
  • legumes,
  • nuts,
  • bananas,
  • potatoes.

Vitamin B2 and the Brain

Beyond its role as a necessary cofactor in the folate cycle, the role of vitamin B6 in amino acid metabolism makes it a rate limiting cofactor in the synthesis of neurotransmitters such as dopamine, serotonin, γ-aminobutyric acid (GABA), noradrenaline and the hormone melatonin. The synthesis of these neurotransmitters is differentially sensitive to vitamin B6 levels, with even mild deficiency resulting in preferential down-regulation of GABA and serotonin synthesis, leading to the removal of inhibition of neural activity by GABA and disordered sleep, behaviour, and cardiovascular function and a loss of hypothalamus-pituitary control of hormone excretion. Vitamin B6 also has a direct effect on immune function and gene transcription/expression and plays a role in brain glucose regulation. More broadly, levels of pyridoxal-5′-phosphate are associated with increased functional indices and biomarkers of inflammation, and levels of pyridoxal-5′-phosphate are down-regulated as a function of more severe inflammation, potentially as a consequence of pyridoxal-5′-phosphate’s role either in the metabolism of tryptophan or in one-carbon metabolism. This role is particularly pertinent as inflammatory processes contribute to the aetiology of numerous pathological states including dementia and cognitive decline(1262).

Brain Specific Symptoms of Deficiency

Irritability, impaired alertness, depression, cognitive decline, dementia, autonomic dysfunction, convulsions.


Pyridoxine, Pyridoxine Hydrochloride and Pyridoxal Phosphate - Description from NCI Thesaurus

 

Pyridoxine and Pyridoxine Hydrochloride - Description from ChemIDplus

 

Pyridoxine - Description from DrugBank

 

Pyridoxine - Description from Wikipedia

 


The supplements containing Vitamin B6


Calm Now, Soothing Stress Formula, 60 Veggie Capsules (Zhou Nutrition)Calm Now, Soothing Stress Formula, 60 Veggie Capsules (Zhou Nutrition)

English version


Calm Now, Soothing Stress Formula, 60 Veggie Capsules (Zhou Nutrition) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
Press pause on stress and get back to balanced with this potent life-saver. Temper your 'tude, channel your inner Zen master, and get back to being your best, calmest self. No matter your walk of life, chances are you've had a DAY before. You know what we mean…time escapes you, people are rubbing...
Calming 5-HTP Stress Support, 100 mg, 120 Vegetarian Capsules (Zenwise Health)Calming 5-HTP Stress Support, 100 mg, 120 Vegetarian Capsules (Zenwise Health)

English version


Calming 5-HTP Stress Support, 100 mg, 120 Vegetarian Capsules (Zenwise Health) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
Zenwise Health 5-HTP is a dietary supplement that contains 100 mg of 5-HTP (5-Hydroxytryptophan) and 10 mg of Vitamin B6 to support mood and stress levels. As a naturally-occurring amino acid, 5-HTP has also been shown to promote sleep management, cognitive function, and appetite control for weight...
L-Cysteine, 500 mg, 100 Tablets (Now Foods)L-Cysteine, 500 mg, 100 Tablets (Now Foods)

English version


L-Cysteine, 500 mg, 100 Tablets (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
L-Cysteine is a non-essential sulfur amino acid, which plays a critical role in methionine, taurine and glutathione metabolism. It is also an important component of hair, nails and the keratin of the skin. L-Cysteine stabilizes protein structure and aids in the formation of collagen, being thereby...
L-Methionine, 500 mg, 100 Capsules (Now Foods)L-Methionine, 500 mg, 100 Capsules (Now Foods)

English version


L-Methionine, 500 mg, 100 Capsules (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
L-Methionine is an essential amino acid, which means that it cannot be manufactured by the body and must be obtained through the diet or by supplementation. L-Methionine supports the production of the cellular radical scavenger glutathione, and thereby assists in natural detoxification processes....
Sports, ZMA, Sports Recovery, 180 Capsules (Now Foods)Sports, ZMA, Sports Recovery, 180 Capsules (Now Foods)

English version


Sports, ZMA, Sports Recovery, 180 Capsules (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
ZMA is a combination of zinc, magnesium and Vitamin B6 designed to maximize absorption and to promote recovery from exercise. Zinc plays a central role in the regulation of cellular growth and tissue repair, as well as the maintenance of a healthy immune system. Magnesium is essential for the...
Water Out, Fluid Balance, 100 Veggie Caps (Now Foods)Water Out, Fluid Balance, 100 Veggie Caps (Now Foods)

English version


Water Out, Fluid Balance, 100 Veggie Caps (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
NOW Water Out is a blend of complementary herbs and nutrients formulated to support healthy urinary tract function and proper bodily fluid balance. Water Out features Dandelion, which has been traditionally used to support the maintenance of water equilibrium, as well as Uva Ursi and Juniper, which...
B-100, Sustained Release, 100 Tablets (Now Foods)B-100, Sustained Release, 100 Tablets (Now Foods)

English version


B-100, Sustained Release, 100 Tablets (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
B-100 Tables provide a full complement of B-Vitamins plus Choline and Inositol. These vitamins works to support energy production, maintain healthy homocysteine metabolism, and promote the health of the nervous system. B-Vitamin are water soluble, and with the exception of B-12, have limited...
B-50, 250 Tablets (Now Foods)B-50, 250 Tablets (Now Foods)

English version


B-50, 250 Tablets (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
B-50 Tabs provide a full complement of B-Vitamins plus Choline and Inositol. These vitamins work to support energy production, maintain healthy homocysteine metabolism, and promote the health of the nervous system. B-Vitamins are water soluble, and with the exception of B-12, have limited storage...
P-5-P, 50 mg, 90 Veg Capsules (Now Foods)P-5-P, 50 mg, 90 Veg Capsules (Now Foods)

English version


P-5-P, 50 mg, 90 Veg Capsules (Now Foods) contains Vitamin B6 in the form of D011732.)">Pyridoxal Phosphate.

 
Vitamin B6 (pyridoxine) acts primarily as an enzyme catalyst in many body processes including energy metabolism and neuro-transmitter function. Before it can be used for this purpose it must be converted into its coenzyme form (P-5-P) by the liver. P-5-P eliminates this step by providing B-6 in its...
B-50, 100 Veg Capsules (Now Foods)B-50, 100 Veg Capsules (Now Foods)

English version


B-50, 100 Veg Capsules (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
B-50 Caps provide a full complement of B-Vitamins plus Choline and Inositol. These vitamins work to support energy production, maintain healthy homocysteine metabolism, and promote the health of the nervous system. B-Vitamins are water soluble, and with the exception of B-12, have limited storage...
B-6, 50 mg, 100 Tablets (Now Foods)B-6, 50 mg, 100 Tablets (Now Foods)

English version


B-6, 50 mg, 100 Tablets (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
Vitamin B6 is a cofactor in numerous enzymatic reactions and is required for the metabolism of fats, carbohydrates, and proteins. It facilitates the conversion of amino acids from another as needed, and is necessary for normal synthesis of hemoglobin, as well as for normal function and production...
Prostate Support, 180 Softgels (Now Foods)Prostate Support, 180 Softgels (Now Foods)

English version


Prostate Support, 180 Softgels (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
NOW Prostate Support is a blend of standardized extracts of herbs and nutrients. Saw Palmetto has been shown in clinical studies to support prostate function. We have provided additional nutritional support with Pumpkin Seed Oil (Cucurbita Pepo), Zinc, Vitamin B6 and Lycopene.
Melatonin, 3 mg, 180 Lozenges (Now Foods)Melatonin, 3 mg, 180 Lozenges (Now Foods)

English version


Melatonin, 3 mg, 180 Lozenges (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
Melatonin is a potent free radical scavenger naturally produced in the pineal gland. It is involved in many of the regulatory processes of the body, including regulation of glandular secretory functions related to the maintenance of normal sleep/wake cycles and aspects of immune systems function.
B-50, 250 Veg Capsules (Now Foods)B-50, 250 Veg Capsules (Now Foods)

English version


B-50, 250 Veg Capsules (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
B-50 Caps provide a full complement of B-Vitamins plus Choline and Inositol. These vitamins work to support energy production, maintain healthy homocysteine metabolism, and promote the health of the nervous system. B-Vitamins are water soluble, and with the exception of B-12, have limited storage...
Solutions, Hair, Skin & Nails, 90 Capsules (Now Foods)Solutions, Hair, Skin & Nails, 90 Capsules (Now Foods)

English version


Solutions, Hair, Skin & Nails, 90 Capsules (Now Foods) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
NOW Solutions Clinically Advanced Hair, Skin & Nails is formulated to nurture hair, skin, and nails form the inside. This product features Cynatine HNS, a revolutionary patented and bioavailable form of solubilized Keratin that can help you maintain full, lustrous hair and nails that are strong and...

If you know of any other quality supplement that has not been yet classified by us, please contact us and we will gladly consider adding it to our catalogue.


Vitamin B6 (Pyridoxine) - References & External links

Vitamin B6 (Pyridoxine)

TBS Ingredient ID (TBSI ID):
Name
Vitamin B6
Synonyms:
Gravidox, Pyridoxol,
Chemical Formula:
C8H11NO3
Molecular Formula:
Pyridoxine - Molecular Formula
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
65-23-6
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).

Show: Pyridoxine - description from ChemIDplus
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Pyridoxine - description from NCI Thesaurus
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.

Show: Pyridoxine - description from DrugBank
Wikipedia:
Wikipedia, the free encyclopedia.
Pyridoxine
Show: Pyridoxine - description from Wikipedia
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
LXNHXLLTXMVWPM-UHFFFAOYSA-N
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
200-603-0
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ECHA:
European Chemicals Agency.
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
3DMet:
3DMET is a database collecting three-dimensional structures of natural metabolites.
MeSH® ID:
Medical Subject Heading (MeSH)

Related substances

Pyridoxine Hydrochloride

Pyridoxine Hydrochloride is the hydrochloride salt form of pyridoxine, a water-soluble vitamin B. Pyridoxine hydrochloride is converted into the active form, pyridoxal 5'-phosphate (PLP), an essential cofactor in many enzymatic activities including synthesis of amino acids, neurotransmitters, and sphingolipids. This vitamin is essential to red blood cell, nervous system, and immune systems functions and helps maintain normal blood glucose levels.

Pyridoxine Hydrochloride

TBS Ingredient ID (TBSI ID):
Name
Pyridoxine Hydrochloride
Synonyms:
Pyridoxine HCl, Pyridoxol Hydrochloride, Alestrol, Becilan, Benadon, Hexavibex, Hexermin, Aderoxin
Chemical Formula:
C8H12ClNO3
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
58-56-0
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).

Show: Pyridoxine Hydrochloride - description from ChemIDplus
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Pyridoxine Hydrochloride - description from NCI Thesaurus
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
ZUFQODAHGAHPFQ-UHFFFAOYSA-N
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
200-386-2
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ECHA:
European Chemicals Agency.
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).

Pyridoxal Phosphate

This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE). (Read more about Pyridoxine Hydrochloride on MeSH: D011732.)

Pyridoxal Phosphate

TBS Ingredient ID (TBSI ID):
Name
Pyridoxal Phosphate
Synonyms:
Pyridoxal 5-Phosphate, Pyridoxal 5'-Phosphate, PLP, P5P
Chemical Formula:
C8H10NO6P
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
NGVDGCNFYWLIFO-UHFFFAOYSA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
54-47-7
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
200-208-3
ECHA:
European Chemicals Agency.
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NSC Number: 82388
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Pyridoxal Phosphate - description from NCI Thesaurus
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
Wikipedia:
Wikipedia, the free encyclopedia.
Pyridoxal_phosphate
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
MeSH® ID:
Medical Subject Heading (MeSH)


The references to scientific articles about Vitamin B6 (Pyridoxine) are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.