C-500, 500 mg, 250 Tablets (21st Century)

This description has been derived from the manufacturer’s / distributor’s website.

Vitamin C is an important antioxidant nutrient that helps neutralize free radicals and supports the immune system.

C-500, 500 mg, 250 Tablets (21st Century) – Ingredients

Calcium
- Calcium Carbonate (CaCO₃ or CCaO₃)
  Calcium Carbonate: Calcium Carbonate, Limestone, Marble, Chalk, Calcite,
  PubChem CID: 10112,
  Chemical Abstracts Service: CAS: 471-34-1,
  ChemIDplus: 471-34-1,
  WHO Anatomical Therapeutic Chemical Classification System: ATC code: A02AC01,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: H0G9379FGK,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS4E2000-3,
  References:
  Allergy / Immune: YAN, Siyu; et al. Calcium Release-Activated Calcium Modulator 1 as a Therapeutic Target in Allergic Skin Diseases. Life sciences, 2019, 228: 152-157. PMID:31055088, PELLETIER, Lucette; SAVIGNAC, Magali Involvement of Ion Channels in Allergy. Current opinion in immunology, 2018, 52: 60-67. PMID:29704811,
  Immune: IZQUIERDO, Jorge-Hernán; et al. Calcium, Channels, Intracellular Signaling and Autoimmunity. Reumatología Clínica (English Edition), 2014, 10.1: 43-47. PMID:24001934.
Vitamin C (Ascorbic Acid)
- Vitamin C (Ascorbic Acid) (C₆H₈O₆)
  Vitamin C protects the immune system, reduces the severity of allergic reactions and helps to fight off infections. Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. Vitamin C supports epithelial barrier function against pathogens and promotes the oxidant scavenging activity of the skin, thereby potentially protecting against environmental oxidative stress. Vitamin C deficiency results in impaired immunity and higher susceptibility to infections. Vitamin C improves immune function, and facilitates enteral uptake of nonheme iron, reduction of folic acid intermediates and synthesis of collagen (wound healing), cortisol, catecholamines and carnitine. Vitamin C depletion may occur scurvy, long-term complications such as increase cardiovascular and neoplasic risks or cataract.
  Vitamin C (Ascorbic Acid): Ascorbic Acid, L-Ascorbic Acid, L(+)-Ascorbic Acid, Vitamin C,
  PubChem CID: 54670067,
  Chemical Abstracts Service: CAS: 50-81-7,
  ChemIDplus: 50-81-7,
  WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11GA01,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: PQ6CK8PD0R,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS2D5190,
  References:
  Vitamins: FAIN, Olivier Vitamin C Deficiency. La Revue de medecine interne, 2004, 25.12: 872-880. PMID:15582167,
  Allergy / Immune: CHAMBIAL, Shailja; et al. Vitamin C in Disease Prevention and Cure: An Overview. Indian Journal of Clinical Biochemistry, 2013, 28.4: 314-328. PMID:24426232, SORICE, Angela; et al. Ascorbic Acid: Its Role in Immune System and Chronic Inflammation Diseases. Mini reviews in medicinal chemistry, 2014, 14.5: 444-452. PMID:24766384,
  Immune: CARR, Anitra C.; et al. Vitamin C and Immune Function. Nutrients, 2017, 9.11: 1211. PMID:29099763, DELLA VOLPE, A.; et al. The Effects of Oral Supplements With Sambucus Nigra, Zinc, Tyndallized Lactobacillus Acidophilus (HA122), Arabinogalactans, Vitamin D, Vitamin E and Vitamin C in Otitis Media With Effusion in Children: A Randomized Controlled Trial. European review for medical and pharmacological sciences, 2019, 23: 6360-6370. PMID:31364144.

Supplement Facts
Name:	C-500, 500 mg, 250 Tablets
Serving Size:	1 Tablet
	Amount Per Serving	% Daily Value
Vitamin C (Ascorbic Acid)	500 mg	833%
Calcium (Calcium Carbonate)	30 mg	3%

Package Quantity
Manufacturer:	21st Century
Manufacturer Code:	22338
UPC Code (gtin12):	740985223383
Count	250

Other ingredients

Stearic acid, cellulose, croscarmellose sodium, hydroxypropyl methylcellulose.

Contains < 2%: Magnesium stearate, maltodextrin, peg, polyvinyl alcohol, silicon dioxide, talc, titanium dioxide.

No added sugar, yeast, preservatives, artificial flavors or colors. Gluten free.

C-500, 500 mg, 250 Tablets – Suggested Use

As a vitamin supplement, adults take one (1) tablet daily with any meal or as directed by your healthcare provider. Do not exceed recommended dosage. Individual results may vary.

Recommended Intake
Dose Unit	Dose Value	Frequency	Target Population
tablet	1	daily	adults

Warnings

Keep out of reach of children. Do not use if product appears to be tampered with or seal is broken. Store at room temperature.
Consult a healthcare provider prior to use if pregnant, nursing, or medications, have a medical condition or are planning a medical procedure. Stop use and contact a physician if adverse reactions occur.

Derminax

Nonacne

The C-500, 500 mg, 250 Tablets (21st Century) dietary supplement is available in Lesotho and many others countries around the world. In Lesotho this supplement contains: Calcium and Vitamin C in its composition.

Detailed descriptions of the ingredients included in the C-500, 500 mg, 250 Tablets (21st Century) dietary supplement:

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