What are the properties of Vitamin B6 in supplements?

The Supplements with Vitamin B6The Supplements with Vitamin B6

The properties of Vitamin B6

Vitamin B6 (pyridoxine C8H11NO3). Ensures proper energy metabolism. It regulates the functioning of the endocrine system and maintains internal balance.

Though all B vitamins are essential, Vitamin B6 is one of the most important. It plays a role in over 100 enzyme reactions in the body, primarily in the metabolism of important amino acids and proteins. Vitamin B6 is one of the most common deficiencies.

Vitamin B6 (pyridoxine) is closely associated with the functions of the nervous, immune and endocrine systems. It also participates in the metabolic processes of proteins, lipids and carbohydrates. Pyridoxine deficiency may result in neurological disorders including convulsions and epileptic encephalopathy and may lead to infant abnormalities(301), (1122).

Recommended Daily Allowance

Vitamin B6 – Recommended Daily Allowance: 1.3/1.3 mg (1.7/1.5 mg >50 year).

Symptoms of Deficiency

Anaemia.

Specific Risk Factors for Deficiency

Alcohol abuse, age-related malabsorption, contraceptive medications.

Dietary Sources

Good Dietary Sources of Vitamin B6:

  • meat,
  • fish,
  • eggs,
  • legumes,
  • nuts,
  • bananas,
  • potatoes.

Vitamin B2 and the Brain

Beyond its role as a necessary cofactor in the folate cycle, the role of vitamin B6 in amino acid metabolism makes it a rate limiting cofactor in the synthesis of neurotransmitters such as dopamine, serotonin, γ-aminobutyric acid (GABA), noradrenaline and the hormone melatonin. The synthesis of these neurotransmitters is differentially sensitive to vitamin B6 levels, with even mild deficiency resulting in preferential down-regulation of GABA and serotonin synthesis, leading to the removal of inhibition of neural activity by GABA and disordered sleep, behaviour, and cardiovascular function and a loss of hypothalamus-pituitary control of hormone excretion. Vitamin B6 also has a direct effect on immune function and gene transcription/expression and plays a role in brain glucose regulation. More broadly, levels of pyridoxal-5′-phosphate are associated with increased functional indices and biomarkers of inflammation, and levels of pyridoxal-5′-phosphate are down-regulated as a function of more severe inflammation, potentially as a consequence of pyridoxal-5′-phosphate’s role either in the metabolism of tryptophan or in one-carbon metabolism. This role is particularly pertinent as inflammatory processes contribute to the aetiology of numerous pathological states including dementia and cognitive decline(1262).

Brain Specific Symptoms of Deficiency

Irritability, impaired alertness, depression, cognitive decline, dementia, autonomic dysfunction, convulsions.


Pyridoxine, Pyridoxine Hydrochloride and Pyridoxal Phosphate - Description from NCI Thesaurus

 

Pyridoxine and Pyridoxine Hydrochloride - Description from ChemIDplus

 

Pyridoxine - Description from DrugBank

 

Pyridoxine - Description from Wikipedia

 


The supplements containing Vitamin B6


Vibovit Junior, proszek w saszetkach o smaku truskawkowym, 2 g, 30 szt. / (Polfa Kutno-leki)Vibovit Junior, proszek w saszetkach o smaku truskawkowym, 2 g, 30 szt. / (Polfa Kutno-leki)

Polish version


Vibovit Junior, proszek w saszetkach o smaku truskawkowym, 2 g, 30 szt. / (Polfa Kutno-leki) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
Vibovit Junior - suplement diety, zawierający witaminy, które wspierają m.in. układ kostny i nerwowy dziecka. Produkt przeznaczony dla dzieci w wieku 4-12 lat. Smak truskawkowy.
Plusssz Magnez Skurcz, tabletki musujące, 20 szt. / (Polski Lek)Plusssz Magnez Skurcz, tabletki musujące, 20 szt. / (Polski Lek)

Polish version


Plusssz Magnez Skurcz, tabletki musujące, 20 szt. / (Polski Lek) contains Vitamin B6.

 
Plusssz Magnez SKURCZ - suplement diety zawierający wyłącznie organiczne sole magnezu oraz potas i witaminy z grupy B. Przeznaczony dla osób dorosłych oraz odczuwających zmęczenie, przy wzmożonym wysiłku fizycznym oraz dodatkowo dla osób, które często piją kawę i mocną herbatę. Smak...
Centrum kompletne od A do Z Silver 50+, tabletki, 30 szt. / (Pfizer)Centrum kompletne od A do Z Silver 50+, tabletki, 30 szt. / (Pfizer)

Polish version


Centrum kompletne od A do Z Silver 50+, tabletki, 30 szt. / (Pfizer) contains Vitamin B6 in the form of Pyridoxine Hydrochloride.

 
Centrum kompletne od A do Z Silver 50+ - suplement diety, zawierający wyjątkową formułę witamin i minerałów dla osób powyżej 50 roku życia, które wspomagają m.in. witalność, zdrowe kości i oczy oraz odporność.

If you know of any other quality supplement that has not been yet classified by us, please contact us and we will gladly consider adding it to our catalogue.


Vitamin B6 (Pyridoxine) - References & External links

Vitamin B6 (Pyridoxine)

TBS Ingredient ID (TBSI ID):
Name
Vitamin B6
Synonyms:
Gravidox, Pyridoxol,
Chemical Formula:
C8H11NO3
Molecular Formula:
Pyridoxine - Molecular Formula
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
65-23-6
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).

Show: Pyridoxine - description from ChemIDplus
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Pyridoxine - description from NCI Thesaurus
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.

Show: Pyridoxine - description from DrugBank
Wikipedia:
Wikipedia, the free encyclopedia.
Pyridoxine
Show: Pyridoxine - description from Wikipedia
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
LXNHXLLTXMVWPM-UHFFFAOYSA-N
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
200-603-0
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ECHA:
European Chemicals Agency.
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
3DMet:
3DMET is a database collecting three-dimensional structures of natural metabolites.
MeSH® ID:
Medical Subject Heading (MeSH)

Related substances

Pyridoxine Hydrochloride

Pyridoxine Hydrochloride is the hydrochloride salt form of pyridoxine, a water-soluble vitamin B. Pyridoxine hydrochloride is converted into the active form, pyridoxal 5'-phosphate (PLP), an essential cofactor in many enzymatic activities including synthesis of amino acids, neurotransmitters, and sphingolipids. This vitamin is essential to red blood cell, nervous system, and immune systems functions and helps maintain normal blood glucose levels.

Pyridoxine Hydrochloride

TBS Ingredient ID (TBSI ID):
Name
Pyridoxine Hydrochloride
Synonyms:
Pyridoxine HCl, Pyridoxol Hydrochloride, Alestrol, Becilan, Benadon, Hexavibex, Hexermin, Aderoxin
Chemical Formula:
C8H12ClNO3
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
58-56-0
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).

Show: Pyridoxine Hydrochloride - description from ChemIDplus
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Pyridoxine Hydrochloride - description from NCI Thesaurus
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
ZUFQODAHGAHPFQ-UHFFFAOYSA-N
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
200-386-2
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ECHA:
European Chemicals Agency.
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).

Pyridoxal Phosphate

This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE). (Read more about Pyridoxine Hydrochloride on MeSH: D011732.)

Pyridoxal Phosphate

TBS Ingredient ID (TBSI ID):
Name
Pyridoxal Phosphate
Synonyms:
Pyridoxal 5-Phosphate, Pyridoxal 5'-Phosphate, PLP, P5P
Chemical Formula:
C8H10NO6P
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
NGVDGCNFYWLIFO-UHFFFAOYSA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
54-47-7
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
200-208-3
ECHA:
European Chemicals Agency.
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NSC Number: 82388
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Pyridoxal Phosphate - description from NCI Thesaurus
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
Wikipedia:
Wikipedia, the free encyclopedia.
Pyridoxal_phosphate
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
MeSH® ID:
Medical Subject Heading (MeSH)


The references to scientific articles about Vitamin B6 (Pyridoxine) are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.