The other active constituents of Gotu Kola are the other triterpene acids asiaticoside A (madecassoside) and asiaticoside B. Flavonoids such as quercetin and kaempferol, and flavone deriviatives such as stigmasterol, sesquiterpenes, sitosterol, and isothankuniside are contained in the leaves. Essential oils and nutrients such as calcium, iron, potassium, phosphorous, beta-carotene, riboflavin, thiamine, vitamin C and niacin are also present in the plant leaves. Gotu Kola contains a high concentration of tannins at approximately 20-25% of its composition.
The triterpene asiaticoside promotes anti-inflammatory activities by inhibiting the inflammatory response induced by lipopolysaccharides (LPS) and stimulates the synthesis of collagen. Animal research suggests that Gotu Kola’s unique saponins may promote neural growth. Gotu Kola’s ability to promote healthy circulation and relieve symptoms of venous insufficiency is due to its saponins which inhibit the enzymes hyaluronidase and elastase. These enzymes breakdown the collagen and elastin matrix outside cells and leads to fluid leakage through the cell wall, resulting in fluid accumulation and swelling, or edema.
Pure Nootropics Gotu Kola Dosage
Pure Nootropics’ Organic Gotu Kola Capsules provide 400 mg per 1 capsule. Suggested use for adults is 1-2 capsules by mouth daily for best results, or as directed by your healthcare practitioner.
Pure Nootropics Gotu Kola Capsules – Ingredients
- Organic Gotu Kola Herb 400mg
- Gotu Kola (Centella Asiatica)
Gotu Kola: known nootropic, revitalizes brain and nervous system, increases attention span, improves long term memory. Species: Centella Asiatica,
Family: Apiaceae Mackinlayaceae,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: IH4FA6A0,
References:
Brain / Mental Clarity: PUTTARAK, Panupong; et al. Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis. Scientific reports, 2017, 7.1: 10646. PMID:28878245, SHINOMOL, G. K.; et al. Exploring the Role of “Brahmi” (Bacopa monnieri and Centella asiatica) in Brain Function and Therapy. Recent patents on endocrine, metabolic & immune drug discovery, 2011, 5.1: 33-49. PMID:22074576,
Cardiovascular Support: RAZALI, Nur Nadia Mohd; NG, Chin Theng; FONG, Lai Yen Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review. Planta medica, 2019, 85.16: 1203-1215. PMID:31539918.
- Triterpenes (C30H48)
Triterpenes: Triterpenes, Triterpene, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS391160.
- Madecassol (C48H78O19)
Madecassol: Madecassol, Asiaticoside, Centelase, Blastostimulina,
PubChem CID: 11954171,
Chemical Abstracts Service: CAS: 16830-15-2,
ChemIDplus: 16830-15-2,
FDA Substance Registration System – Unique Ingredient Identifier: UNII: PKO39VY215,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISEDBB60.
- Brahmoside
Brahmoside: Brahmoside, Brahminoside, PubChem CID: 395762, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED9450.
- Asiatic Acid (C30H48O5)
Asiatic Acid: Asiatic Acid, Asiantic Acid, Dammarolic Acid,
PubChem CID: 119034,
Chemical Abstracts Service: CAS: 464-92-6,
ChemIDplus: 464-92-6,
FDA Substance Registration System – Unique Ingredient Identifier: UNII: 9PA5A687X5,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED6D40.
- Madecassic Acid (C30H48O6)
Madecassic Acid: Madecassic Acid, Brahmic Acid, 6Beta-Hydroxyasiatic Acid,
PubChem CID: 73412,
Chemical Abstracts Service: CAS: 18449-41-7,
ChemIDplus: 18449-41-7,
FDA Substance Registration System – Unique Ingredient Identifier: UNII: M7O1N24J82,
The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISED4630. - Brahmoside
- Madecassol (C48H78O19)
- Triterpenes (C30H48)
Manufacturer: | Pure Nootropics |
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Dietary supplements similar to Pure Nootropics Gotu Kola Capsules
The Pure Nootropics Gotu Kola Capsules dietary supplement is available in Canada and many others countries around the world. In Canada this supplement contains: Asiatic Acid, Brahmoside, Gotu Kola, Madecassic Acid, Madecassol, Terpenes and Triterpenes in its composition.
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