What are the properties of Vitamin B12 in supplements?

The Supplements with Vitamin B12The Supplements with Vitamin B12

The properties of Vitamin B12

Vitamin B12 is necessary for DNA synthesis, neurological function, and red blood cell formation. The active forms of B12 are called methylcobalamin and 5-deoxyadenosylcobalamin. Vitamin B12 is a cofactor for methionine synthase and thereby affects the synthesis of nearly 100 substrates including DNA, RNA, and proteins. The recommended dietary allowance of vitamin B12 is 2.4 mcg for adult U.S. populations. There is no established upper limit for vitamin B12 intake, as it has a low potential for toxicity(1173).

Recommended Daily Allowance

Vitamin B12 – Recommended Daily Allowance: 2.4 (µg).

Symptoms of Deficiency

Megaloblastic anaemia, peripheral neuropathy, spinal cord lesions, metabolic abnormalities.

Specific Risk Factors for Deficiency

Age-related malabsorption, vegetarians, vegans, Genetic polymorphisms.

Dietary Sources

Good Dietary Sources of Vitamin B12:

  • meat, fish and other animal products.

Vitamin B12 and the Brain

Vitamin B12 – A British study published in the journal Neurology found that folks with low vitamin B12 were six times more likely to have brain atrophy compared to people with highest levels. Further studies of vitamin B12 link this essential water-soluble vitamin to higher cognition, performance and both episodic and semantic memory.

Brain Specific Symptoms of Deficiency

Affective disorders, behaviour changes, psychosis, cognitive impairment/decline, dementia (inc Alzheimer’s disease and vascular dementia).

B12 supplement

  • Boost Energy Levels,
  • Reduces Depression,
  • Helps Metabolize Proteins around the body:
    • Good for Brain Health,
    • Digestive System,
    • Healthy Hair,
    • Skin & Nails

Cyanocobalamin - Description from NCI Thesaurus

 

Cyanocobalamin - Description from ChemIDplus

 

Cyanocobalamin - Description from DrugBank

 

Cyanocobalamin - Description from Wikipedia

 


The supplements containing Vitamin B12

Cal-Mag, Stress Formula, 100 Tablets (Now Foods)Cal-Mag, Stress Formula, 100 Tablets (Now Foods)

English version

Minerals Stress / Relaxation TBSS ID:
Cal-Mag, Stress Formula, 100 Tablets (Now Foods) contains Vitamin B12.

 

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Cal-Mag Stress Formula is a mix of Calcium, Magnesium, Vitamin C, and a full range of B-vitamin which aid in the production of energy. Vitamin C, in addition to its function as an antioxidant, helps to support a normal adrenal response. This product also provides the daily recommended levels of...
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Methyl B-12, 1,000 mcg, 100 Lozenges (Now Foods)Methyl B-12, 1,000 mcg, 100 Lozenges (Now Foods)

English version

Hair / Skin Care Vitamins TBSS ID:
Methyl B-12, 1,000 mcg, 100 Lozenges (Now Foods) contains Vitamin B12 in the form of Methylcobalamin.

 

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Vitamin B12 is necessary for the production of energy from fats and proteins and is well known for its critical role in DNA synthesis, as well as in homocysteine metabolism. Methylcobalamin is the co-enzyme form of Vitamin B12 that has been found to be especially critical in the maintenance of a...
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Thyroid Energy, 90 Veg Capsules (Now Foods)Thyroid Energy, 90 Veg Capsules (Now Foods)

English version

Hair / Skin Care TBSS ID:
Thyroid Energy, 90 Veg Capsules (Now Foods) contains Vitamin B12 in the form of Methylcobalamin.

 

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NOW Thyroid Energy is a complete nutritional supplement for the support of a healthy thyroid gland. NOW has combined Iodine and Tyrosine, the two constituents necessary for the synthesis of thyroid secretions. The minerals Selenium, Zinc and Copper have been added as cofactors needed for normal...
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Folic Acid with Vitamin B12, 800 mcg, 250 Tablets (Now Foods)Folic Acid with Vitamin B12, 800 mcg, 250 Tablets (Now Foods)

English version

Vitamins TBSS ID:
Folic Acid with Vitamin B12, 800 mcg, 250 Tablets (Now Foods) contains Vitamin B12.

 

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Folic Acid is very important member of the B-vitamin family required for DNA synthesis and genetic repair, making an adequate supply essential for rapidly dividing cells, such as red blood cells. Folic acid is also necessary for the synthesis of methionine from homocysteine and can help to...
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Solutions, Hair, Skin & Nails, 90 Capsules (Now Foods)Solutions, Hair, Skin & Nails, 90 Capsules (Now Foods)

English version

Hair / Skin / Nails TBSS ID:
Solutions, Hair, Skin & Nails, 90 Capsules (Now Foods) contains Vitamin B12 in the form of Methylcobalamin.

 

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NOW Solutions Clinically Advanced Hair, Skin & Nails is formulated to nurture hair, skin, and nails form the inside. This product features Cynatine HNS, a revolutionary patented and bioavailable form of solubilized Keratin that can help you maintain full, lustrous hair and nails that are strong and...
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Thyroid Energy, 180 Veg Capsules (Now Foods)Thyroid Energy, 180 Veg Capsules (Now Foods)

English version

Hair / Skin Care TBSS ID:
Thyroid Energy, 180 Veg Capsules (Now Foods) contains Vitamin B12 in the form of Methylcobalamin.

 

Learn More (GB)
NOW Thyroid Energy is a complete nutritional supplement for the support of a healthy thyroid gland. NOW has combined Iodine and Tyrosine, the two constituents necessary for the synthesis of thyroid secretions. The minerals Selenium, Zinc and Copper have been added as cofactors needed for normal...
Learn More (GB)

If you know of any other quality supplement that has not been yet classified by us, please contact us and we will gladly consider adding it to our catalogue.


Vitamin B12 (cobalamin, cyanocobalamin) - References & External links

Vitamin B12 (Cyanocobalamin)

TBS Ingredient ID (TBSI ID):
Name
Vitamin B12
Synonyms:
Cobalamin, Crystamine, Anacobin
Chemical Formula:
C63H88CoN14O14P
Molecular Formula:
Cyanocobalamin - Molecular Formula
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)		68-19-9
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
Show: Cyanocobalamin - description from ChemIDplus
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NCI Thesaurus:
National Cancer Institute - NCI.
Show: Cyanocobalamin - description from NCI Thesaurus
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
Show: Cyanocobalamin - description from DrugBank
Wikipedia:
Wikipedia, the free encyclopedia.		Cyanocobalamin
Show: Cyanocobalamin - description from Wikipedia
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard		FDJOLVPMNUYSCM-WZHZPDAFSA-L
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number		200-680-0
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ECHA:
European Chemicals Agency.
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).

Related substances

Methylcobalamin

Methylcobalamin

TBS Ingredient ID (TBSI ID):
Name
Methylcobalamin
Synonyms:
Mecobalamin, Algobaz, Vitamin B12 Analog, Methyl-B12, Methyl Vitamin B12, Methycobal, Cobamet, Cobametin
Chemical Formula:
C63H91CoN13O14P
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard		ZFLASALABLFSNM-UHFFFAOYSA-L
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)		13422-55-4
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
ECHA:
European Chemicals Agency.
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number		236-535-3
Wikipedia:
Wikipedia, the free encyclopedia.		Methylcobalamin
MeSH® ID:
Medical Subject Heading (MeSH)
UNII:
FDA Substance Registration System - Unique Ingredient Identifier

The references to scientific articles about Vitamin B12 (cobalamin, cyanocobalamin) are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.