What are the properties of Elderberry in supplements?

Elderberry - References & External links

Elderberry (Sambucus Nigra)

The references to scientific articles about Elderberry are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• The general properties of Elderberry:
  • NO AUTHORS LISTED, . Elderberry. In: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US), 2006–2018, 12.3: . PMID:30000895
• The properties of Elderberry as a Natural Nutrient:
  Elderberry fruit preparations may provide antioxidant, antiviral and antiproliferative effects.
  • PLISZKA, Barbara. Polyphenolic Content, Antiradical Activity, Stability and Microbiological Quality of Elderberry (Sambucus Nigra L.) Extracts. Acta Scientiarum Polonorum Technologia Alimentaria, 2017, 16.4: 393-401. PMID:29241318
    Conclusions: The research findings may support the selection of certain cultivars for industrial applications. The high stability of anthocyanins and low level of microbiological impurities in elderberry extracts ensure the high quality of such a raw material in food and pharmaceutical processing.
• Influence of Elderberry on the Immune Response:
  Sambucus Nigra has a long ethnobotanical history across many disparate cultures as a treatment for viral infection and is currently one of the most-used medicinal plants worldwide. Elderberry is active against human pathogenic bacteria as well as influenza viruses.
  • KRAWITZ, Christian; et al. Inhibitory Activity of a Standardized Elderberry Liquid Extract Against Clinically-Relevant Human Respiratory Bacterial Pathogens and Influenza A and B Viruses. BMC complementary and alternative medicine, 2011, 11.1: 16. PMID:21352539
    Conclusion: Rubini elderberry liquid extract is active against human pathogenic bacteria as well as influenza viruses. The activities shown suggest that additional and alternative approaches to combat infections might be provided by this natural product.
  • SHAHSAVANDI, Shahla; EBRAHIMI, Mohammad Majid; FARAHANI, Ameneh Hasaninejad. Interfering With Lipid Raft Association: A Mechanism to Control Influenza Virus Infection By Sambucus Nigra. Iranian journal of pharmaceutical research: IJPR, 2017, 16.3: 1147. PMID:29201101
  • CHEN, Christie; et al. Sambucus Nigra Extracts Inhibit Infectious Bronchitis Virus at an Early Point During Replication. BMC veterinary research, 2014, 10.1: 24. PMID:24433341
    Conclusions: These results demonstrate that S. nigra extract can inhibit IBV at an early point in infection, probably by rendering the virus non-infectious. They also suggest that future studies using S. nigra extract to treat or prevent IBV or other coronaviruses are warranted.
  • PORTER, Randall S.; BODE, Robert F. A Review of the Antiviral Properties of Black Elder (Sambucus Nigra L.) Products. Phytotherapy Research, 2017, 31.4: 533-554. PMID:28198157
  • VLACHOJANNIS, J. E.; CAMERON, Melainie; CHRUBASIK, Sigrun. A Systematic Review on the Sambuci Fructus Effect and Efficacy Profiles. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2010, 24.1: 1-8. PMID:19548290
  • AKRAM, Muhammad; et al. Antiviral Potential of Medicinal Plants Against HIV, HSV, Influenza, Hepatitis, and Coxsackievirus: A Systematic Review. Phytotherapy Research, 2018, 32.5: 811-822. PMID:29356205
  • DELLA VOLPE, A.; et al. The Effects of Oral Supplements With Sambucus Nigra, Zinc, Tyndallized Lactobacillus Acidophilus (HA122), Arabinogalactans, Vitamin D, Vitamin E and Vitamin C in Otitis Media With Effusion in Children: A Randomized Controlled Trial. European review for medical and pharmacological sciences, 2019, 23: 6360-6370. PMID:31364144
    Conclusions: OS with immune-stimulating molecules should be considered as a supporting therapy in children affected by recurrent episodes of UAI associated with OME due to their capacity to improve the immune response and reduce the inflammatory phenomena. OS can improve the fibroendoscopic findings by restoring middle ear ventilation, in addition to their ability to reduce inflammation in the middle ear.
  • MAKARKOV, Alexander I.; et al. Plant-made Virus-Like Particles Bearing Influenza Hemagglutinin (HA) Recapitulate Early Interactions of Native Influenza Virions With Human Monocytes/Macrophages. Vaccine, 2017, 35.35: 4629-4636. PMID:28712489
    Conclusions: Plant-made VLPs bearing influenza HA not only mimic the structure of influenza virions to some degree but also recapitulate key features of the initial virus-APC interaction. These observations may help to explain the balanced humoral and cellular responses to plant-made VLP vaccines.
• The properties of Elderberry preventing Cold / Flu:
  • HAWKINS, Jessie; et al. Black Elderberry (Sambucus Nigra) Supplementation Effectively Treats Upper Respiratory Symptoms: A Meta-Analysis of Randomized, Controlled Clinical Trials. Complementary therapies in medicine, 2019, 42: 361-365. PMID:30670267
  • CHEN, Christie; et al. Sambucus Nigra Extracts Inhibit Infectious Bronchitis Virus at an Early Point During Replication. BMC veterinary research, 2014, 10.1: 24. PMID:24433341
    Conclusions: These results demonstrate that S. nigra extract can inhibit IBV at an early point in infection, probably by rendering the virus non-infectious. They also suggest that future studies using S. nigra extract to treat or prevent IBV or other coronaviruses are warranted.
  • ROXAS, Mario; JURENKA, Julie. Colds and Influenza: A Review of Diagnosis and Conventional, Botanical, and Nutritional Considerations. Alternative Medicine Review, 2007, 12.1: . PMID:17397266
• The properties of Elderberry in supporting diabets treatment:
  • BADESCU, Magda; et al. Effects of Sambucus Nigra and Aronia Melanocarpa Extracts on Immune System Disorders Within Diabetes Mellitus. Pharmaceutical biology, 2015, 53.4: 533-539. PMID:25327310
    Conclusions: Natural polyphenols extracted from S. nigra and A. melanocarpa modulate specific and non-specific immune defenses in insulin-deficiency diabetes and reduce the inflammatory status and self-sustained pancreatic insulitis.
• The properties of Elderberry for Weight Loss:
  • ZIELIńSKA-WASIELICA, Joanna; et al. Elderberry ( Sambucus nigra L.) Fruit Extract Alleviates Oxidative Stress, Insulin Resistance, and Inflammation in Hypertrophied 3T3-L1 Adipocytes and Activated RAW 264.7 Macrophages. Foods, 2019, 8.8: 326. PMID:31398785