What are the properties of CBD in supplements?

The properties of CBD

Cannabidiol is a phytocannabinoid derived from Cannabis species, which is devoid of psychoactive activity, with analgesic, anti-inflammatory, antineoplastic and chemopreventive activities. Upon administration, cannabidiol (CBD) exerts its anti-proliferative, anti-angiogenic and pro-apoptotic activity through various mechanisms, which likely do not involve signaling by cannabinoid receptor 1 (CB1), CB2, or vanilloid receptor 1. CBD stimulates endoplasmic reticulum (ER) stress and inhibits AKT/mTOR signaling, thereby activating autophagy and promoting apoptosis. In addition, CBD enhances the generation of reactive oxygen species (ROS), which further enhances apoptosis. This agent also upregulates the expression of intercellular adhesion molecule 1 (ICAM-1) and tissue inhibitor of matrix metalloproteinases-1 (TIMP1) and decreases the expression of inhibitor of DNA binding 1 (ID-1). This inhibits cancer cell invasiveness and metastasis. CBD may also activate the transient receptor potential vanilloid type 2 (TRPV2), which may increase the uptake of various cytotoxic agents in cancer cells. The analgesic effect of CBD is mediated through the binding of this agent to and activation of CB1.



The supplements containing CBD


GreenLeaf - CBD OilGreenLeaf - CBD Oil

English version


GreenLeaf – CBD Oil contains CBD.
CBD oils have been used and praised by people struggling with various ailments for years. The oil owns its beneficial features to the presence of a compound called cannabidiol. Each GreenLeaf CBD Oil bottle contains 5%. Until recently it was available mainly abroad, today you can enjoy its merits...

If you know of any other quality supplement that has not been yet classified by us, please contact us and we will gladly consider adding it to our catalogue.


CBD - References & External links

CBD (Cannabidiol)

TBS Ingredient ID (TBSI ID):
NameMolecular Formula:
CBD
Synonyms:
Epidiolex
C21H30O2
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
QHMBSVQNZZTUGM-ZWKOTPCHSA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
3556-78-3
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
MeSH® ID:
Medical Subject Heading (MeSH)
CTD:
Comparative Toxicogenomics Database (CTD)
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
LIPIDMAPS:
LIPID MAPS Lipidomics Gateway
KNApSAcK:
A Comprehensive Species-Metabolite Relationship Database
J-GLOBAL:
J-GLOBAL
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier

The references to scientific articles about CBD are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.