What are the properties of Vitamin B9 in supplements?

The Supplements with Vitamin B9The Supplements with Vitamin B9

The properties of Vitamin B9

Folate is another water-soluble B vitamin and includes naturally occurring food folate and folic acid (fully oxidized monoglutamate). Folate is a coenzyme in the synthesis of nucleic acids and in amino acid metabolism. It exists in the plasma as 5-methyl-tetrahydrofolate, while about half of the total body content exists in the liver. The recommended dietary allowance of food folate is 400 mcg daily for adults, which is supported by required fortification of some foods in the USA. The tolerable upper intake level of folate is 1000 mcg. While most people in the USA ingest adequate amounts of folate, certain groups are at risk for deficiency (usually in association with poor diet, alcoholism, or a malabsorptive disorder). Folate deficiency can cause hair, skin, and nail changes(1173).

Your body uses folic acid to help make DNA and RNA and works with vitamin B12 to make red blood cells and use iron throughout the body. It’s nothing short of poetry for your brain – evidence suggests B vitamins like folic acid may have slower cognitive decline than other folks.

Recommended Daily Allowance

Vitamin B9 – Recommended Daily Allowance: 400 (µg).

Symptoms of Deficiency

Megaloblastic anaemia, peripheral neuropathy, spinal cord lesions, metabolic abnormalities.

Brain Specific Symptoms of Deficiency

Affective disorders, behaviour changes, psychosis, cognitive impairment/decline, dementia (inc Alzheimer’s disease and vascular dementia).

Specific Risk Factors for Deficiency

Common genetic polymorphisms (inc. MTHFR C667T) Low Riboflavin and B12.

Dietary Sources

Good Dietary Sources of Vitamin B9:

  • leafy vegetables,
  • legumes,
  • citrus fruits.

Folic Acid - Description from NCI Thesaurus

 

Folic Acid - Description from ChemIDplus

 

Folic Acid - Description from DrugBank

 

Folic Acid - Description from Wikipedia

 


The supplements containing Vitamin B9


DerminaxDerminax

English version


Derminax contains Vitamin B9.

 
Gels, creams and ointments are not effective because they fight symptoms not the cause. Derminax is different. It works from the inside. Derminax is a unique blend of natural ingredients which eliminates spots, blackheads, lumps, redness and blemishes caused by skin inflammation.
Vitabase - Enfūz (Advanced)Vitabase - Enfūz (Advanced)

English version


Vitabase – Enfūz (Advanced) contains Vitamin B9.

 
Enfūz Advanced is a complete nutritional supplement program designed to meet your basic nutritional needs. It contains vitamins, minerals, antioxidants, fish oil, extra vitamin D, and more. Choosing which health supplements to take on a regular basis can be a very frustrating process. Often...
B-Complex "100", 100 Vegetable Capsules (Solgar)B-Complex "100", 100 Vegetable Capsules (Solgar)

English version


B-Complex “100”, 100 Vegetable Capsules (Solgar) contains Vitamin B9.

 
Each required nutrient in the Vitamin B Complex performs a unique role in maintaining proper metabolic functioning, while nutritionally supporting the body during the occasional stress of daily living. B Complex vitamins are needed for the metabolism of carbohydrates, fats and proteins, which...
Folic Acid with Vitamin B-12, 800 mcg, 250 Tablets (Now Foods)Folic Acid with Vitamin B-12, 800 mcg, 250 Tablets (Now Foods)

English version


Folic Acid with Vitamin B-12, 800 mcg, 250 Tablets (Now Foods) contains Vitamin B9.

 
Folic Acid is very important member of the B-vitamin family required for DNA synthesis and genetic repair, making an adequate supply essential for rapidly dividing cells, such as red blood cells. Folic acid is also necessary for the synthesis of methionine from homocysteine and can help to...
Folate as Metafolin, 400 mcg, 100 Tablets (Solgar)Folate as Metafolin, 400 mcg, 100 Tablets (Solgar)

English version


Folate as Metafolin, 400 mcg, 100 Tablets (Solgar) contains Vitamin B9 in the form of Levomefolic Acid.

 
Folic Acid must first be converted to its active form by a series of biochemical steps, before it is able to be used by the body. Metafolin (L-methylfolate) requires no conversion because it is bioidentical to the bio-active form. In other words, it is 'body-ready'. This can be useful for...
Cal-Mag, Stress Formula, 100 Tablets (Now Foods)Cal-Mag, Stress Formula, 100 Tablets (Now Foods)

English version


Cal-Mag, Stress Formula, 100 Tablets (Now Foods) contains Vitamin B9.

 
Cal-Mag Stress Formula is a mix of Calcium, Magnesium, Vitamin C, and a full range of B-vitamin which aid in the production of energy. Vitamin C, in addition to its function as an antioxidant, helps to support a normal adrenal response. This product also provides the daily recommended levels of...

If you know of any other quality supplement that has not been yet classified by us, please contact us and we will gladly consider adding it to our catalogue.


Vitamin B9 (folic acid, folacin) - References & External links

Vitamin B9 (Folic Acid)

TBS Ingredient ID (TBSI ID):
Name
Vitamin B9
Synonyms:
Folacin, Pteroylglutamic Acid, Pteroylmonoglutamic Acid, Folate
Chemical Formula:
C19H19N7O6
Molecular Formula:
Folic Acid - Molecular Formula
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
59-30-3
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).

Show: Folic Acid - description from ChemIDplus
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Folic Acid - description from NCI Thesaurus
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.

Show: Folic Acid - description from DrugBank
Wikipedia:
Wikipedia, the free encyclopedia.
Folate
Show: Folic Acid - description from Wikipedia
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
OVBPIULPVIDEAO-LBPRGKRZSA-N
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
200-419-0
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ECHA:
European Chemicals Agency.
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
3DMet:
3DMET is a database collecting three-dimensional structures of natural metabolites.
MeSH® ID:
Medical Subject Heading (MeSH)

Related substances

Levomefolate Calcium

Levomefolate Calcium

TBS Ingredient ID (TBSI ID):
Name
Levomefolate Calcium
Synonyms:
Metafolin, Calcium L-Methylfolate, Levomefolinate Calcium, Nutrifolin, Bodyfolin
Chemical Formula:
C20H23CaN7O6
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
VWBBRFHSPXRJQD-QNTKWALQSA-L
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
151533-22-1
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier

Levomefolic Acid

Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma. It is transported across the membranes including the blood-brain barrier into various tissues where it plays an essential role in the DNA synthesis, cysteine cycle and regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate (THF). Levomefolate is approved as a food additive and is designated a GRAS (generally regarded as safe) compound. It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the stability required for use as a supplement. Supplementation of levomefolic acid is desired over folic acid due to reduced potential for masking vitamin B12 deficiency symptoms.

Levomefolic Acid

TBS Ingredient ID (TBSI ID):
Name
Levomefolic Acid
Synonyms:
L-5-MTHF, Methylfolate, Levomefolinic Acid, Levomefolate, 5-Methyltetrahydrofolate, L-5-Methyltetrahydrofolate, (6S)-5-MTHF, Quatrefolic
Chemical Formula:
C20H25N7O6
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
ZNOVTXRBGFNYRX-STQMWFEESA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
31690-09-2
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
603-809-2
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
UNII:
FDA Substance Registration System - Unique Ingredient Identifier


The references to scientific articles about Vitamin B9 (folic acid, folacin) are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.