What are the properties of Vitamin B2 in supplements?

The Supplements with Vitamin B2The Supplements with Vitamin B2

The properties of Vitamin B2

Riboflavin, also known as vitamin B2, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to prevent and treat riboflavin deficiency and prevent migraines. It may be given by mouth or injection. It is required by the body for cellular respiration. Normal doses are safe during pregnancy.

Recommended Daily Allowance

Vitamin B2 – Recommended Daily Allowance: 1.3/1.1 mg.

Symptoms of Deficiency

Weakness, oral pain/tenderness, burning/itching of the eyes, dermatitis, anaemia.

Specific Risk Factors for Deficiency

Inherited riboflavin malabsorption/utilisation (10%–15% prevalence).

Dietary Sources

Good Dietary Sources of Vitamin B2:

  • dairy products,
  • leafy vegetables,
  • legumes,
  • liver,
  • kidneys,
  • yeast,
  • mushrooms.

Vitamin B2 & Hair Loss

Vitamin B2 (riboflavin) is a component of two important coenzymes: flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). FMN and FAD represent 90% of dietary riboflavin, and both play roles in cellular development and function, metabolism of fats, and energy production. The body stores only small amounts of riboflavin, in the liver, heart, and kidneys. Riboflavin deficiency—while extremely rare in the USA—can cause hair loss(1173).

Vitamin B2 and the Brain

The two flavoprotein coenzymes derived from riboflavin, FMN and FAD are crucial rate limiting factors in most cellular enzymatic processes. As an example, they are crucial for the synthesis, conversion and recycling of niacin, folate and vitamin B6, and for the synthesis of all heme proteins, including hemeglobin, nitric oxide synthases, P450 enzymes, and proteins involved in electron transfer and oxygen transport and storage. The flavoproteins are also co-factors in the metabolism of essential fatty acids in brain lipids, the absorption and utilisation of iron, and the regulation of thyroid hormones. Dysregulation of any of these processes by riboflavin deficiency would be associated with its own broad negative consequences for brain function. Riboflavin derivatives also have direct antioxidant properties and increase endogenous antioxidant status as essential cofactors in the glutathione redox cycle(1262).

Brain Specific Symptoms of Deficiency

Fatigue, personality change, brain dysfunction.


Riboflavin - Description from NCI Thesaurus

 

Riboflavin - Description from ChemIDplus

 

Riboflavin - Description from DrugBank

 

Riboflavin - Description from Wikipedia

 


The supplements containing Vitamin B2

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Vitamin B2 (riboflavin) - References & External links

Vitamin B2 (Riboflavin)

TBS Ingredient ID (TBSI ID):
Name
Vitamin B2
Synonyms:
Riboflavina, Riboflavinum, Lactoflavin, Riboflavine, Vitamin G, Beflavin, Beflavine
Chemical Formula:
C17H20N4O6
Molecular Formula:
Riboflavin - Molecular Formula
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)		83-88-5
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
Show: Riboflavin - description from ChemIDplus
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
UNII:
FDA Substance Registration System - Unique Ingredient Identifier
NCI Thesaurus:
National Cancer Institute - NCI.
Show: Riboflavin - description from NCI Thesaurus
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
Show: Riboflavin - description from DrugBank
Wikipedia:
Wikipedia, the free encyclopedia.		Riboflavin
Show: Riboflavin - description from Wikipedia
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard		AUNGANRZJHBGPY-SCRDCRAPSA-N
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number		201-507-1
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ECHA:
European Chemicals Agency.
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).

The references to scientific articles about Vitamin B2 (riboflavin) are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.