What are the properties of Magnesium in supplements?

Magnesium - References & External links

Magnesium

Related substances

Magnesium Oxide

Magnesium oxide has poor solubility in water and is poorly absorbed from the gut. Magnesium oxide is used for relief of heartburn and dyspepsia, as an antacid, magnesium supplement, and as a short-term laxative. It is also used to improve symptoms of indigestion. Side effects of magnesium oxide may include nausea and cramping. In quantities sufficient to obtain a laxative effect, side effects of long-term use include enteroliths resulting in bowel obstruction.

Magnesium Oxide

TBS Ingredient ID (TBSI ID):	IS371590-1
Name
Magnesium Oxide Synonyms: Magnesia, Periclase, Seawater Magnesia
Chemical Formula:
MgO
Molecular Formula:
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	14792
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	CPLXHLVBOLITMK-UHFFFAOYSA-N
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	1309-48-4
NIST: The National Institute of Standards and Technology (NIST)	1309-48-4
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	1309-48-4
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	215-171-9
ICSC Number: International Labour Organization (ILO)	0504
CTD: Comparative Toxicogenomics Database (CTD)	D008277
MeSH® ID: Medical Subject Heading (MeSH)	D008277
ATC code: WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics	A02AA02
UNII: FDA Substance Registration System - Unique Ingredient Identifier	3A3U0GI71G

Magnesium Stearate

Magnesium stearate is produced by the reaction of sodium stearate with magnesium salts or by treating magnesium oxide with stearic acid. Some nutritional supplements specify that the sodium stearate used in manufacturing magnesium stearate is produced from vegetable-derived stearic acid.

Magnesium Stearate

TBS Ingredient ID (TBSI ID):	IS371590-2
Name
Magnesium Stearate Synonyms: Magnesium Octadecanoate, Magnesium Distearate, Synpro 90, Stearic acid, magnesium salt, Magnesium Dioctadecanoate
Chemical Formula:
C36H70MgO4 or Mg(C18H35O2)2
Molecular Formula:
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	11177
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	HQKMJHAJHXVSDF-UHFFFAOYSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	557-04-0
NIST: The National Institute of Standards and Technology (NIST)	557-04-0
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	557-04-0
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	209-150-3

Magnesium Citrate

Magnesium citrate is used medicinally as a saline laxative and to completely empty the bowel prior to a major surgery or colonoscopy. It is available without a prescription, both as a generic and under various brand names. It is also used in the pill form as a magnesium dietary supplement. It contains 11.23% magnesium by weight. Compared to trimagnesium citrate, it is much more water-soluble, less alkaline, and contains less magnesium. Magnesium citrate, as a supplement in pill form, is useful for the prevention of kidney stones.

Magnesium Citrate

TBS Ingredient ID (TBSI ID):	IS371590-3
Name
Magnesium Citrate Synonyms: Trimagnesium Dicitrate, Trimagnesiumdicitrat, Magnesium Citrate Hydrate
Chemical Formula:
C6H6MgO7 or C12H10Mg3O14
Molecular Formula:
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	6099959
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	PLSARIKBYIPYPF-UHFFFAOYSA-H
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	3344-18-1
NIST: The National Institute of Standards and Technology (NIST)	3344-18-1
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	3344-18-1
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	222-093-9
ATC code: WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics	A06AD19

Magnesium Lactate

Magnesium Lactate

TBS Ingredient ID (TBSI ID):	IS371590-4
Name
Magnesium Lactate Synonyms: DL-Magnesium Lactate, Magnesium L-Lactate Trihydrate, Bis(Lactato)Magnesium
Chemical Formula:
C6H10MgO6
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	6536825
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	OVGXLJDWSLQDRT-UHFFFAOYSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	18917-93-6
NIST: The National Institute of Standards and Technology (NIST)	18917-93-6
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	18917-93-6
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	242-671-4
ATC code: WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics	A12CC06
DSSTox Substance ID: United States Environmental Protection Agency (EPA).	DTXSID20872620

Milk Of Magnesia

Milk Of Magnesia

TBS Ingredient ID (TBSI ID):	IS371590-5
Name
Milk Of Magnesia Synonyms: Magnesium Hydroxide, Magnesiumhydroxide
Chemical Formula:
H2MgO2
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	14791
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	VTHJTEIRLNZDEV-UHFFFAOYSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	1309-42-8
NIST: The National Institute of Standards and Technology (NIST)	1309-42-8
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	1309-42-8
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	215-274-9
DSSTox Substance ID: United States Environmental Protection Agency (EPA).	DTXSID4049662
ChEBI: Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.	6637
KEGG: Kyoto Encyclopedia of Genes and Genomes (KEGG)	C07876
ChEMBL: An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)	ChEMBL1200718
ATC code: WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics	A02AA04
UNII: FDA Substance Registration System - Unique Ingredient Identifier	NBZ3QY004S

Magnesium Carbonate

Magnesium Carbonate

TBS Ingredient ID (TBSI ID):	IS371590-6
Name
Magnesium Carbonate Synonyms: Magnesite, Carbonic Acid, Magnesium Salt, Kimboshi, Magmaster, Apolda, Destab, Magfy
Chemical Formula:
MgCO3· nH2O or MgCO3 or CMgO3
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	11029
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	ZLNQQNXFFQJAID-UHFFFAOYSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	546-93-0
NIST: The National Institute of Standards and Technology (NIST)	546-93-0
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	546-93-0
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	208-915-9
ICSC Number: International Labour Organization (ILO)	0969
RTECS:	OM2470000
DSSTox Substance ID: United States Environmental Protection Agency (EPA).	DTXSID4049660
ChEBI: Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.	31793
ChEMBL: An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)	ChEMBL1200736
ATC code: WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics	A02AA01
UNII: FDA Substance Registration System - Unique Ingredient Identifier	0IHC698356

Magnesium Glycinate

Magnesium Glycinate

TBS Ingredient ID (TBSI ID):	IS371590-7
Name
Magnesium Glycinate Synonyms: Magnesium Bisglycinate, Magnesium Diglycinate, Magnesium 2-Aminoacetate, Glycine, Magnesuim Salt
Chemical Formula:
C4H8MgN2O4
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	84645
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	AACACXATQSKRQG-UHFFFAOYSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	14783-68-7
NIST: The National Institute of Standards and Technology (NIST)	14783-68-7
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	14783-68-7
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	238-852-2
DSSTox Substance ID: United States Environmental Protection Agency (EPA).	DTXSID90163815
UNII: FDA Substance Registration System - Unique Ingredient Identifier	IFN18A4Y6B

Magnesium Malate

Magnesium Malate

TBS Ingredient ID (TBSI ID):	IS371590-8
Name
Magnesium Malate Synonyms: 2-Hydroxybutanedioic Acid Magnesium Salt
Chemical Formula:
C4H4MgO5
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	164748
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	JFQQIWNDAXACSR-UHFFFAOYSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	869-06-7
NIST: The National Institute of Standards and Technology (NIST)	869-06-7
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	869-06-7
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	212-784-3
DSSTox Substance ID: United States Environmental Protection Agency (EPA).	DTXSID70893860

Magnesium Gluconate

Magnesium Gluconate

TBS Ingredient ID (TBSI ID):	IS371590-9
Name
Magnesium Gluconate
Chemical Formula:
C12H22MgO14
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	11418570
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	CTUVIUYTHWPELF-IYEMJOQQSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	3632-91-5
NIST: The National Institute of Standards and Technology (NIST)	3632-91-5
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	3632-91-5
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	222-848-2
ChEMBL: An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)	ChEMBL2107145
KEGG: Kyoto Encyclopedia of Genes and Genomes (KEGG)	D04835
ATC code: WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics	A12CC03
UNII: FDA Substance Registration System - Unique Ingredient Identifier	TH52F4317B

Magnesium L-Threonate

Magnesium L-threonate is a nutritional supplement containing the L-threonate form of magnesium (Mg) that can be used to normalize Mg levels in the body. Upon administration, Mg is utilized by the body for many biochemical functions and reactions including: bone and muscle function, protein and fatty acid formation, activation of B vitamins, blood clotting, insulin secretion, and ATP formation. Mg also serves as a catalyst for many enzymes throughout the body. In addition, magnesium improves the functioning of the immune system by enhancing the expression of natural killer activating receptor NKG2D in cytotoxic T-lymphocytes and natural killer (NK) cells. This increases their anti-viral and anti-tumor cytotoxic effects.

Magnesium L-Threonate

TBS Ingredient ID (TBSI ID):	IS371590-10
Name
Magnesium L-Threonate
Chemical Formula:
C8H14MgO10
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	45489777
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	YVJOHOWNFPQSPP-BALCVSAKSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	778571-57-6
NIST: The National Institute of Standards and Technology (NIST)	778571-57-6
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	778571-57-6
DSSTox Substance ID: United States Environmental Protection Agency (EPA).	DTXSID30670457
NCI Thesaurus: National Cancer Institute - NCI.	C123781
UNII: FDA Substance Registration System - Unique Ingredient Identifier	1Y26ZZ0OTM

Magnesium Aspartate

Magnesium aspartate, the chelated magnesium salt of aspartic acid, it is a mineral supplement. One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter. This form of magnesium supplementation has increased bioavailability compared to oxide and citrate.

Magnesium Aspartate

TBS Ingredient ID (TBSI ID):	IS371590-11
Name
Magnesium Aspartate Synonyms: Magnesium L-Aspartate, Magnesium l-Aspartate Dihydrate
Chemical Formula:
C8H12MgN2O8
Molecular Formula:
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	16211203
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	RXMQCXCANMAVIO-CEOVSRFSSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	18962-61-3
NIST: The National Institute of Standards and Technology (NIST)	18962-61-3
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	18962-61-3
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	218-191-6
ECHA: European Chemicals Agency.	100.016.538
MeSH® ID: Medical Subject Heading (MeSH)	D001224
DSSTox Substance ID: United States Environmental Protection Agency (EPA).	DTXSID10273965
ATC code: WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics	A12CC05
UNII: FDA Substance Registration System - Unique Ingredient Identifier	082H981FMA

Magnesium Caprylate

Magnesium Caprylate

TBS Ingredient ID (TBSI ID):	IS371590-12
Name
Magnesium Caprylate Synonyms: Magnesium Dioctanoate, Magnesium Octanoate
Chemical Formula:
C16H30MgO4
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	19595724
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	HPBJPFJVNDHMEG-UHFFFAOYSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	3386-57-0
NIST: The National Institute of Standards and Technology (NIST)	3386-57-0
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	3386-57-0
DSSTox Substance ID: United States Environmental Protection Agency (EPA).	DTXSID2052021
UNII: FDA Substance Registration System - Unique Ingredient Identifier	K7EHJ964F3

Magnesium Taurate

Magnesium Taurate

TBS Ingredient ID (TBSI ID):	IS371590-13
Name
Magnesium Taurate Synonyms: Magnesium Ditaurate, Magnesium 2-Aminoethanesulfonate
Chemical Formula:
C4H12MgN2O6S2
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	13343447
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	YZURQOBSFRVSEB-UHFFFAOYSA-L
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	334824-43-0
NIST: The National Institute of Standards and Technology (NIST)	334824-43-0
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	334824-43-0
UNII: FDA Substance Registration System - Unique Ingredient Identifier	RCM1N3D968

The references to scientific articles about Magnesium are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• The general properties of Magnesium:
  • ROTTER, Iwona; et al. Relationship between serum magnesium concentration and metabolic and hormonal disorders in middle-aged and older men. Magnesium research, 2015, 28.3: 99-107. PMID:26507751
• The properties of Magnesium as an Electrolyte:
  Magnesium plays a crucial role in the function of hundreds of processes in our body. It is a cofactor to more than 300 enzymatic systems that regulate much of our biochemistry such as muscle and nerve function, energy production, protein synthesis, blood pressure regulation, and blood sugar control.
  • WEGLICKI, William; et al. Potassium, magnesium, and electrolyte imbalance and complications in disease management. Clinical and Experimental Hypertension, 2005, 27.1: 95-112. PMID:15773233
  • WESTER, Per Olof. Electrolyte balance in heart failure and the role for magnesium ions. The American journal of cardiology, 1992, 70.10: 44-49. PMID:1414894
• Influence of Magnesium on the Immune Response:
  Magnesium (Mg) has a strong relation with the immune system, in both nonspecific and specific immune response, also known as innate and acquired immune response.
  • TAM, M.; et al. Possible Roles of Magnesium on the Immune System. European journal of clinical nutrition, 2003, 57.10: 1193-1197. PMID:14506478
• The properties of Magnesium boosting Brain / Mental Clarity:
  • BOURRE, Jean-Marie. Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. Journal of Nutrition Health and Aging, 2006, 10.5: 377. PMID:17066209
  • HUSKISSON, E.; MAGGINI, S.; RUF, M. The influence of micronutrients on cognitive function and performance. Journal of international medical research, 2007, 35.1: 1-19. PMID:17408051
  • KIRKLAND, Anna; SARLO, Gabrielle; HOLTON, Kathleen. The role of magnesium in neurological disorders. Nutrients, 2018, 10.6: 730. PMID:29882776
  • EBY, Karen L. Rapid recovery from major depression using magnesium treatment. Medical hypotheses, 2006, 67.2: 362-370. PMID:16542786
  • ABBASI, Behnood; KIMIAGAR, M.; SADEGHNIIAT, K.; SHIRAZI, M. M.; HEDAYATI, M.; RASHIDKHANI, B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences, 2012, 17.12: 1161. PMID:16542786
    CONCLUSION: Supplementation of magnesium appears to improve subjective measures of insomnia such as ISI score, sleep efficiency, sleep time and sleep onset latency, early morning awakening, and likewise, insomnia objective measures such as concentration of serum renin, melatonin, and serum cortisol, in elderly people.
• The properties of Magnesium against stress:
  • POUTEAU, Etienne; et al. Superiority of Magnesium and Vitamin B6 Over Magnesium Alone on Severe Stress in Healthy Adults With Low Magnesemia: A Randomized, Single-Blind Clinical Trial. PloS one, 2018, 13.12: e0208454. PMID:30562392
    Conclusions: These findings suggest oral Mg supplementation alleviated stress in healthy adults with low magnesemia and the addition of vitamin B6 to Mg was not superior to Mg supplementation alone. With regard to subjects with severe/extremely severe stress, this study provides clinical support for greater benefit of Mg combined with vitamin B6.
• The properties of Magnesium for Joint / Bone Health:
  • DIMAI, H. P.; PORTA, S.; WIRNSBERGER, G.; LINDSCHINGER, M.; PAMPERL, I.; DOBNIG, H.; WILDERS-TRUSCHNIG, M.; LAU, K. H. Daily oral magnesium supplementation suppresses bone turnover in young adult males. The Journal of Clinical Endocrinology & Metabolism, 1998, 83.8: 2742-2748. PMID:9709941
• The properties of Magnesium improving Heart Health:
  • SHECHTER, Michael. Magnesium and cardiovascular system. Magnesium research, 2010, 23.2: 60-72. PMID:20353903
• The properties of Magnesium for people active in sport:
  • CINAR, Vedat; et al. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion. Biological trace element research, 2011, 140.1: 18-23. PMID:20352370
• The role of Magnesium in PMS Support:
  • MCCABE, Delia; et al. The Impact of Essential Fatty Acid, B Vitamins, Vitamin C, Magnesium and Zinc Supplementation on Stress Levels in Women: A Systematic Review. 2017, 15.2, 402-453: . PMID:
    Conclusion: The current review suggests that EFAs may be effective in reducing prenatal stress and salivary cortisol and may reduce anxiety during premenstrual syndrome and during menopause in the absence of depression. Magnesium and vitamin B6 may be effective in combination in reducing premenstrual stress, and vitamin B6 alone may reduce anxiety effectively in older women. High-dose sustained-release vitamin C may reduce anxiety and mitigate increased blood pressure in response to stress.
• The properties of Magnesium against Menopause syndrome:
  • MCCABE, Delia; et al. The Impact of Essential Fatty Acid, B Vitamins, Vitamin C, Magnesium and Zinc Supplementation on Stress Levels in Women: A Systematic Review. JBI database of systematic reviews and implementation reports, 2017, 15.2: 402-453. PMID:28178022
    Conclusion: The current review suggests that EFAs may be effective in reducing prenatal stress and salivary cortisol and may reduce anxiety during premenstrual syndrome and during menopause in the absence of depression. Magnesium and vitamin B6 may be effective in combination in reducing premenstrual stress, and vitamin B6 alone may reduce anxiety effectively in older women. High-dose sustained-release vitamin C may reduce anxiety and mitigate increased blood pressure in response to stress.