What are the properties of D-Glucosamine in supplements?

D-Glucosamine - References & External links

D-Glucosamine

TBS Ingredient ID (TBSI ID):	ISB12790
Name
D-Glucosamine Synonyms: Glucosamine, 2-Amino-2-Deoxy-D-Glucopyranose, 2-Amino-2-Deoxy-D-Glucose, Chitosamine, D-(+)-Glucosamine, 2-Deoxy-2-Amino-D-Glucose, 2-Amino-2-Deoxyglucose
Chemical Formula:
C6H13NO5
Molecular Formula:
Classification Type	Identifier
PubChem CID: U.S. National Library of Medicine (PubChem)	439213
InChI Key: International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard	MSWZFWKMSRAUBD-IVMDWMLBSA-N
CAS: A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)	3416-24-8
NIST: The National Institute of Standards and Technology (NIST)	3416-24-8
ChemIDplus: United States National Library of Medicine - TOXNET (Toxicology Data Network).	3416-24-8
EC Number: A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number	222-311-2
ChEBI: Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.	5417 Show: D-Glucosamine - description from ChEBI
KEGG: Kyoto Encyclopedia of Genes and Genomes (KEGG)	C00329
3DMet: 3DMET is a database collecting three-dimensional structures of natural metabolites.	B04670
LiverTox: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]	NBK547949 Show: D-Glucosamine - description from LiverTox
UNII: FDA Substance Registration System - Unique Ingredient Identifier	N08U5BOQ1K

The references to scientific articles about D-Glucosamine are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• The properties of D-Glucosamine preventing Arthritis / Joint Pain:
  Glucosamine stimulates the formation of hyaluronic acid, which retains water in the connective tissue, providing elasticity; releases joint pain, improves its functioning, and has no side effects.
  • VASILIADIS, Haris S.; TSIKOPOULOS, Konstantinos. Glucosamine and chondroitin for the treatment of osteoarthritis. World journal of orthopedics, 2017, 8.1: 1. PMID:28144573
  • MCALINDON, Timothy E.; et al. Glucosamine and Chondroitin for Treatment of OsteoarthritisA Systematic Quality Assessment and Meta-analysis. Jama, 2000, 283.11: 1469-1475.
    Conclusions:Trials of glucosamine and chondroitin preparations for OA symptoms demonstrate moderate to large effects, but quality issues and likely publication bias suggest that these effects are exaggerated. Nevertheless, some degree of efficacy appears probable for these preparations.
  • ZHU, Xiaoyue; et al. Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials. Journal of orthopaedic surgery and research, 2018, 13.1: 1-9. PMID:29980200
    Conclusions: Given the effectiveness of these symptomatic slow-acting drugs, oral chondroitin is more effective than placebo on relieving pain and improving physical function. Glucosamine showed effect on stiffness outcome. Regarding on the limited number of combination therapy, further studies need to investigate the accurate effectiveness. This information accompanied with the tolerability and economic costs of included treatments would be conducive to making decisions for clinicians.