What are the properties of Chondroitin in supplements?

The properties of Chondroitin

A chondroitin is a chondrin derivative.

Types include:

  • Chondroitin sulfate,
  • Dermatan sulfate.

Chondroitin as a supplement is now commonly used in treating the joint disease of osteoarthritis as well as glucosamine. In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine. Chondroitin’s effect toward the articular cartilage integrity as it is part of the proteoglycan molecules. The cartilage proteoglycan synthesis can speed up as chondroitin is going through the pathway of the alimentary canal. Research has been conducted to show the effectiveness of chondroitin and results indicate that it helps to manage pain in knee and hip, slow down the progression and also recovery.



The supplements containing Chondroitin

Advanced Strength Joint Support, 180 Tablets (Zenwise Health)Advanced Strength Joint Support, 180 Tablets (Zenwise Health)

English version

Joint / Bone Health Osteoporosis / Bone Health TBSS ID:
Advanced Strength Joint Support, 180 Tablets (Zenwise Health) contains Chondroitin in the form of Chondroitin Sulfate.

 

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Zenwise Health Joint Support contains 1500 mg Glucosamine, 1200 mg chondroitin, and 1000 mg MSM, which may support overall hip and joint health. This advanced formula features a blend  of curcumin and hyaluronic acid, which may promote joint  strength and mobility to encourage an active healthy...
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Collagen Extreme with BioCell Collagen, 120 Capsules (Paradise Herbs)Collagen Extreme with BioCell Collagen, 120 Capsules (Paradise Herbs)

English version

Joint / Bone Health Minerals Osteoporosis / Bone Health TBSS ID:
Collagen Extreme with BioCell Collagen, 120 Capsules (Paradise Herbs) contains Chondroitin in the form of Chondroitin Sulfate.

 

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Collagen is a vital protein of our body. Having youthful looking skin & hair with optimum levels of moisture, joint flexibility and comfort seem to be essential especially for those of us who want to look and feel our best.
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Glucosamine & Chondroitin with MSM, 180 Capsules (Now Foods)Glucosamine & Chondroitin with MSM, 180 Capsules (Now Foods)

English version

Arthritis / Joint Pain Joint / Bone Health Osteoporosis / Bone Health TBSS ID:
Glucosamine & Chondroitin with MSM, 180 Capsules (Now Foods) contains Chondroitin in the form of Chondroitin Sulfate.

 

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NOW Glucosamine & Chondroitin known nutrients available for the support of healthy joints in one dietary supplement. Scientific studies have demonstrated that Glucosamine and Chondroitin can promote normal joint mobility and comfort. MSM is present as a naturally occurring sulfur compound for...
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If you know of any other quality supplement that has not been yet classified by us, please contact us and we will gladly consider adding it to our catalogue.


Chondroitin - References & External links

Chondroitin

TBS Ingredient ID (TBSI ID):
Name
Chondroitin
Synonyms:
Chondroitin Disaccharide, Chondroitin-D-Glucuronate
Chemical Formula:
C14H21NO11
Molecular Formula:
Chondroitin - Molecular Formula
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard		DLGJWSVWTWEWBJ-HGGSSLSASA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)		9007-27-6
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number		232-695-3
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.

Related substances

Chondroitin Sulfate

Chondroitin Sulfate

TBS Ingredient ID (TBSI ID):
Name
Chondroitin Sulfate
Chemical Formula:
C13H21NO15S
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard		KXKPYJOVDUMHGS-OSRGNVMNSA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)		9007-28-7
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number		232-696-9
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
MeSH® ID:
Medical Subject Heading (MeSH)
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)

The references to scientific articles about Chondroitin are not meant to imply that any products treat, cure, or diagnose any disease or human condition. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

  • The properties of Chondroitin preventing Arthritis / Joint Pain:
    Chondroitin stimulates metabolic processes in the joints, slows down and stops cartilage destruction, and starts its restoration.
    • SINGH, Jasvinder A.; et al. Cochrane Database of Systematic Reviews, 2015, 2015: 1. PMID:
      conclusions: A review of randomized trials of mostly low quality reveals that chondroitin (alone or in combination with glucosamine) was better than placebo in improving pain in participants with osteoarthritis in short-term studies. The benefit was small to moderate with an 8 point greater improvement in pain (range 0 to 100) and a 2 point greater improvement in Lequesne's index (range 0 to 24), both seeming clinically meaningful. These differences persisted in some sensitivity analyses and not others. Chondroitin had a lower risk of serious adverse events compared with control. More high-quality studies are needed to explore the role of chondroitin in the treatment of osteoarthritis. The combination of some efficacy and low risk associated with chondroitin may explain its popularity among patients as an over-the-counter supplement.
    • ZHU, Xiaoyue; et al. Journal of orthopaedic surgery and research, 2018, 13.1: 1-9. PMID:
      Conclusions: Given the effectiveness of these symptomatic slow-acting drugs, oral chondroitin is more effective than placebo on relieving pain and improving physical function. Glucosamine showed effect on stiffness outcome. Regarding on the limited number of combination therapy, further studies need to investigate the accurate effectiveness. This information accompanied with the tolerability and economic costs of included treatments would be conducive to making decisions for clinicians.
    • VASILIADIS, Haris S.; TSIKOPOULOS, Konstantinos. World journal of orthopedics, 2017, 8.1: 1. PMID:
    • MCALINDON, Timothy E.; et al. Jama, 2000, 283.11: 1469-1475.
      Conclusions:Trials of glucosamine and chondroitin preparations for OA symptoms demonstrate moderate to large effects, but quality issues and likely publication bias suggest that these effects are exaggerated. Nevertheless, some degree of efficacy appears probable for these preparations.