Melatonin, 3 mg, 180 Lozenges (Now Foods)

This description has been derived from the manufacturer’s / distributor’s website.

Melatonin is a potent free radical scavenger naturally produced in the pineal gland. It is involved in many of the regulatory processes of the body, including regulation of glandular secretory functions related to the maintenance of normal sleep/wake cycles and aspects of immune systems function.

Melatonin, 3 mg, 180 Lozenges (Now Foods) – Ingredients

Vitamin B
- Vitamin B6 (Pyridoxine) (C₈H₁₁NO₃)
  Vitamin B6 (Pyridoxine): Pyridoxine, Gravidox, Pyridoxol, Vitamin B6,
  PubChem CID: 1054,
  Chemical Abstracts Service: CAS: 65-23-6,
  ChemIDplus: 65-23-6,
  WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA02,
  FDA Substance Registration System – Unique Ingredient Identifier: UNII: KV2JZ1BI6Z,
  The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS264CB0,
  References:
  Immune: BIRD, Ranjana P.; et al. The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. In: Advances in food and nutrition research. Academic Press, 2018, 83: 151-194. PMID:29477221, BESSLER, H.; DJALDETTI, M. Vitamin B6 Modifies the Immune Cross-Talk Between Mononuclear and Colon Carcinoma Cells. Folia biologica, 2016, 62.1: 47. PMID:27085010.
  - Vitamin B6 (Pyridoxine Hydrochloride) (C₈H₁₂ClNO₃)
    Vitamin B6 (Pyridoxine Hydrochloride): Pyridoxine Hydrochloride, Pyridoxine HCl, Pyridoxol Hydrochloride, Alestrol, Becilan, Benadon, Hexavibex, Hexermin, Aderoxin, PubChem CID: 6019, Chemical Abstracts Service: CAS: 58-56-0, ChemIDplus: 58-56-0, WHO Anatomical Therapeutic Chemical Classification System: ATC code: A11HA02, FDA Substance Registration System – Unique Ingredient Identifier: UNII: 68Y4CF58BV, The Best Supplements – Unique Ingredient Identifier: TBSI ID: IS264CB0-1, References: Immune: ULVIK, Arve; et al. Association of Plasma B-6 Vitamers With Systemic Markers of Inflammation Before and After Pyridoxine Treatment in Patients With Stable Angina Pectoris. The American journal of clinical nutrition, 2012, 95.5: 1072-1078. PMID:22492365, Sleep Well: ASPY, Denholm J.; MADDEN, Natasha A.; DELFABBRO, Paul Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep. Perceptual and motor skills, 2018, 125.3: 451-462. PMID:29665762.
Melatonin (C₁₃H₁₆N₂O₂)
Besides regulating the circadian rhythm it works as a natural antioxidant with immune stimulatory and anti-cancer properties. The primary physiological function of melatonin, whose secretion adjusts to night length, is to convey information concerning the daily cycle of light and darkness to body structures. Melatonin is involved in numerous biological functions including circadian rhythm, sleep, the stress response, aging, and immunity. Besides regulating the circadian rhythm it works as a natural antioxidant with immune stimulatory and anti-cancer properties.
Melatonin: Melatonin, Melatonine, N-Acetyl-5-Methoxytryptamine, 5-Methoxy-N-Acetyltryptamine, Circadin, Melatol, Melatonex, Melovine, PubChem CID: 896, Chemical Abstracts Service: CAS: 73-31-4, ChemIDplus: 73-31-4, WHO Anatomical Therapeutic Chemical Classification System: ATC code: N05CH01, FDA Substance Registration System – Unique Ingredient Identifier: UNII: JL5DK93RCL, The Best Supplements – Unique Ingredient Identifier: TBSI ID: ISAFEF10, References: Immune: VINTHER, Anna Gry; et al. The Influence of Melatonin on the Immune System and Cancer. Ugeskr Laeger, 2015, 177.21: V10140568. PMID:26027592, CARRILLO-VICO, Antonio; et al. Melatonin: Buffering the Immune System. International journal of molecular sciences, 2013, 14.4: 8638-8683. PMID:23609496, Sleep Well: ZISAPEL, Nava New Perspectives on the Role of Melatonin in Human Sleep, Circadian Rhythms and Their Regulation. British journal of pharmacology, 2018, 175.16: 3190-3199. PMID:29318587.

Supplement Facts
Name:	Melatonin, 3 mg, 180 Lozenges
Serving Size:	1 Lozenge
	Amount Per Serving	% Daily Value
Vitamin B6 (Pyridoxine Hcl)	3 mg	150%
Melatonin	3 mg	†
† Daily Value not established.

Package Quantity
Manufacturer:	Now Foods
Manufacturer Code:	03259
UPC Code (gtin12):	733739032591
Count	180

Other ingredients

Fructose, cellulose, stearic acid (vegetable source), mannitol, natural peppermint flavor, sorbitol and magnesium stearate (vegetable source).

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Melatonin, 3 mg, 180 Lozenges – Suggested Use

Take 1 lozenge just prior to bedtime as needed. Chew lozenge or hold in mouth until dissolved and swallow.

Recommended Intake
Dose Unit	Dose Value	Frequency	Target Population
lozenge	1	daily	adults

Warnings

For adults only. May cause drowsiness. Do not operate a vehicle or heavy machinery following consumption of melatonin. Consult physician if pregnant/nursing, taking medication (especially sedatives, immunosuppressants or anticoagulans), or have a medical condition (including diabetes, auto-immune conditions, depressive disorders, cardiovascular conditions and epilepsy). Keep out of reach of children.
Do not eat freshness packet. Keep in bottle.
Natural color variation may occur in this product.

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The Melatonin, 3 mg, 180 Lozenges (Now Foods) dietary supplement is available in Zambia and many others countries around the world. In Zambia this supplement contains: B Vitamins, Melatonin and Vitamin B6 in its composition.

Detailed descriptions of the ingredients included in the Melatonin, 3 mg, 180 Lozenges (Now Foods) dietary supplement:

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