What are the properties of Creatine in supplements?

The properties of Creatine

Creatine is an organic compound with the nominal formula (H2N)(HN)CN(CH3)CH2CO2H. This species exists in various modifications (tautomers) in solution. Creatine is found in vertebrates where it facilitates recycling of adenosine triphosphate (ATP), the energy currency of the cell, primarily in muscle and brain tissue. Recycling is achieved by converting adenosine diphosphate (ADP) back to ATP via donation of phosphate groups. Creatine also acts as a buffer.

Creatine use can increase maximum power and performance in high-intensity anaerobic repetitive work (periods of work and rest) by 5 to 15%. Creatine has no significant effect on aerobic endurance, though it will increase power during short sessions of high-intensity aerobic exercise.

Creatine is reported to increase cognitive performance, especially in individuals with inadequate intakes in their diet and is claimed by some sources to be a nootropic supplement.

Creatine-monohydrate is suitable for vegetarians and vegans, as the raw materials used for the production of the supplement have no animal origin.

According to a clinical study focusing on people with various muscular dystrophies, using a pure form of creatine monohydrate can be beneficial in rehabilitation after injuries and immobilization.

A clinical study has shown that the intake of pure, high-quality creatine alone, or in combination with exercise, may reduce and delay age-related muscle atrophy, by improving fat-free body mass, muscle strength and endurance, while simultaneously improving bone density.


Creatine - Description from DrugBank

 

Creatine - Description from NCI Thesaurus

 

Creatine - Description from HMDB

 

Creatine - Description from ChEBI

 


The supplements containing Creatine


Sports, Creatine Monohydrate, 750 mg, 120 Capsules (Now Foods)Sports, Creatine Monohydrate, 750 mg, 120 Capsules (Now Foods)

English version


Sports, Creatine Monohydrate, 750 mg, 120 Capsules (Now Foods) contains Creatine in the form of Creatine Monohydrate.

 
Creatine is a compound that occurs naturally in the body, primarily in skeletal muscle. Creatine's function is to serve as a precursor to Adenosine Triphosphate (ATP), the form of chemical energy used by all cells. Body stores of Creatine create a pool of readily available ATP for energy, which is...

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Creatine

TBS Ingredient ID (TBSI ID):
Name
Creatine
Synonyms:
Creatin, Kreatin, N-amidinosarcosine
Chemical Formula:
C4H9N3O2
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
CVSVTCORWBXHQV-UHFFFAOYSA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
57-00-1
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
200-306-6
ECHA:
European Chemicals Agency.
NSC Number: 8752
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
ChEBI:
Chemical Entities of Biological Interest (ChEBI) - Dictionary of molecular entities focused on "small" chemical compounds. ChEBI is part of the EMBL-European Bioinformatics Institute.

Show: Creatine - description from ChEBI
ChEMBL:
An open data resource of binding, functional and ADMET bioactivity data (ChEMBL)
ATC code:
WHO ATC Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of drugs. This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics
KEGG:
Kyoto Encyclopedia of Genes and Genomes (KEGG)
CTD:
Comparative Toxicogenomics Database (CTD)
MeSH® ID:
Medical Subject Heading (MeSH)
HMDB:
The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.

Show: Creatine - description from HMDB
NCI Thesaurus:
National Cancer Institute - NCI.

Show: Creatine - description from NCI Thesaurus
DrugBank:
The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.

Show: Creatine - description from DrugBank
UNII:
FDA Substance Registration System - Unique Ingredient Identifier

Related substances

Creatine Monohydrate

Creatine Monohydrate is the monohydrate form of creatine similar or identical to endogenous creatine produced in the liver, kidneys, and pancreas. Creatine, in phosphate form, helps supply energy to muscle cells for contraction. After intense effort, when ATP deposits are depleted, creatine phosphate donates phosphate groups toward the fast synthesis of ATP. Dietary supplementation with creatine may improve muscle wasting associated with cancer and other chronic diseases. (NCI Thesaurus)

Creatine Monohydrate

TBS Ingredient ID (TBSI ID):
Name
Creatine Monohydrate
Synonyms:
Creatine Hydrate, 2-(1-Methylguanidino)Acetic Acid Hydrate
Chemical Formula:
C4H11N3O3
Classification TypeIdentifier
PubChem CID:
U.S. National Library of Medicine (PubChem)
InChI Key:
International Chemical Identifier hash (InChIKey) computed from chemical structure using the International Union of Pure and Applied Chemistry (IUPAC) standard
MEJYXFHCRXAUIL-UHFFFAOYSA-N
CAS:
A proprietary registry number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society (ACS)
6020-87-7
NIST:
The National Institute of Standards and Technology (NIST)
ChemIDplus:
United States National Library of Medicine - TOXNET (Toxicology Data Network).
EC Number:
A seven-digit regulatory identifier currently assigned by the European Chemicals Agency (ECHA) known as a European Community (EC) number
611-954-8
ECHA:
European Chemicals Agency.
DSSTox Substance ID:
United States Environmental Protection Agency (EPA).
NCI Thesaurus:
National Cancer Institute - NCI.
UNII:
FDA Substance Registration System - Unique Ingredient Identifier