An unusual lectin from stinging nettle (Urtica dioica) rhizomes.

Peumans Willy J., De Ley Marc, Broekaert Willem F.
FEBS letters, 1984


An unusual lectin has been isolated from stinging nettle (Urtica dioica L.) rhizomes. It is a small (8.5 kDa) monomeric protein with high contents of glycine, cysteine and tryptophan. The U. dioica agglutinin (UDA) is not blood group-specific and is specifically inhibited by N-acetylglucosamine oligomers. As compared to other plant lectins, UDA has a very low specific agglutination activity. Nevertheless, it induces HulFN-γ in human lymphocytes at concentrations comparable to those of other inducers.


Urtica dioica, Lectin, Interferon, Lymphocyte


UDA, Urtica dioica agglutinin, SDS-PAGE, SDS-polyacrylamide gel electrophoresis, Con A, concanavalin A, SEA, staphylococcal enterotoxin A

Category:General properties of Urtica Dioica

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